The H3 loop of antibodies shows unique structural characteristics
Regep, Cristian, Georges, Guy, Shi, Jiye, Popovic, Bojana, Deane, Charlotte M.
Published in Proteins, structure, function, and bioinformatics (01.07.2017)
Published in Proteins, structure, function, and bioinformatics (01.07.2017)
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SAbPred: a structure-based antibody prediction server
Dunbar, James, Krawczyk, Konrad, Leem, Jinwoo, Marks, Claire, Nowak, Jaroslaw, Regep, Cristian, Georges, Guy, Kelm, Sebastian, Popovic, Bojana, Deane, Charlotte M
Published in Nucleic acids research (08.07.2016)
Published in Nucleic acids research (08.07.2016)
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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome
Richter, Hans, Satz, Alexander L, Bedoucha, Marc, Buettelmann, Bernd, Petersen, Ann C, Harmeier, Anja, Hermosilla, Ricardo, Hochstrasser, Remo, Burger, Dominique, Gsell, Bernard, Gasser, Rodolfo, Huber, Sylwia, Hug, Melanie N, Kocer, Buelent, Kuhn, Bernd, Ritter, Martin, Rudolph, Markus G, Weibel, Franziska, Molina-David, Judith, Kim, Jin-Ju, Santos, Javier Varona, Stihle, Martine, Georges, Guy J, Bonfil, R. Daniel, Fridman, Rafael, Uhles, Sabine, Moll, Solange, Faul, Christian, Fornoni, Alessia, Prunotto, Marco
Published in ACS chemical biology (18.01.2019)
Published in ACS chemical biology (18.01.2019)
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ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins
Abanades, Brennan, Wong, Wing Ki, Boyles, Fergus, Georges, Guy, Bujotzek, Alexander, Deane, Charlotte M
Published in Communications biology (29.05.2023)
Published in Communications biology (29.05.2023)
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Journal Article
Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
Schaefer, Wolfgang, Regula, Jörg T, Bähner, Monika, Schanzer, Jürgen, Croasdale, Rebecca, Dürr, Harald, Gassner, Christian, Georges, Guy, Kettenberger, Hubert, Imhof-Jung, Sabine, Schwaiger, Manfred, Stubenrauch, Kay G, Sustmann, Claudio, Thomas, Markus, Scheuer, Werner, Klein, Christian
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (05.07.2011)
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Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices
Dengl, Stefan, Mayer, Klaus, Bormann, Felix, Duerr, Harald, Hoffmann, Eike, Nussbaum, Bianca, Tischler, Michael, Wagner, Martina, Kuglstatter, Andreas, Leibrock, Lea, Buldun, Can, Georges, Guy, Brinkmann, Ulrich
Published in Nature communications (02.10.2020)
Published in Nature communications (02.10.2020)
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Journal Article
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies
Niederfellner, Gerhard, Lammens, Alfred, Mundigl, Olaf, Georges, Guy J., Schaefer, Wolfgang, Schwaiger, Manfred, Franke, Andreas, Wiechmann, Kornelius, Jenewein, Stefan, Slootstra, Jerry W., Timmerman, Peter, Brännström, Annika, Lindstrom, Frida, Mössner, Ekkehard, Umana, Pablo, Hopfner, Karl-Peter, Klein, Christian
Published in Blood (14.07.2011)
Published in Blood (14.07.2011)
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Journal Article
Targeted chain-exchange-mediated reconstitution of a split type-I cytokine for conditional immunotherapy
Vasic, Vedran, Buldun, Can, Ritz, Manfred, Dickopf, Steffen, Georges, Guy J., Spick, Christian, Peuker, Alessa, Meier, Thomas, Mayer, Klaus, Brinkmann, Ulrich
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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Journal Article
Prediction of VH-VL domain orientation for antibody variable domain modeling
Bujotzek, Alexander, Dunbar, James, Lipsmeier, Florian, Schäfer, Wolfgang, Antes, Iris, Deane, Charlotte M., Georges, Guy
Published in Proteins, structure, function, and bioinformatics (01.04.2015)
Published in Proteins, structure, function, and bioinformatics (01.04.2015)
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Journal Article
SCALOP: sequence-based antibody canonical loop structure annotation
Wong, Wing Ki, Georges, Guy, Ros, Francesca, Kelm, Sebastian, Lewis, Alan P, Taddese, Bruck, Leem, Jinwoo, Deane, Charlotte M
Published in Bioinformatics (15.05.2019)
Published in Bioinformatics (15.05.2019)
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Journal Article
Ensembles in solution as a new paradigm for antibody structure prediction and design
Fernández-Quintero, Monica L., Georges, Guy, Varga, Janos M., Liedl, Klaus R.
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope
Wong, Wing Ki, Robinson, Sarah A, Bujotzek, Alexander, Georges, Guy, Lewis, Alan P, Shi, Jiye, Snowden, James, Taddese, Bruck, Deane, Charlotte M
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Assessing developability early in the discovery process for novel biologics
Fernández-Quintero, Monica L., Ljungars, Anne, Waibl, Franz, Greiff, Victor, Andersen, Jan Terje, Gjølberg, Torleif T., Jenkins, Timothy P., Voldborg, Bjørn Gunnar, Grav, Lise Marie, Kumar, Sandeep, Georges, Guy, Kettenberger, Hubert, Liedl, Klaus R., Tessier, Peter M., McCafferty, John, Laustsen, Andreas H.
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
Germline-Dependent Antibody Paratope States and Pairing Specific VH-VL Interface Dynamics
Fernández-Quintero, Monica L., Kroell, Katharina B., Bacher, Lisa M., Loeffler, Johannes R., Quoika, Patrick K., Georges, Guy, Bujotzek, Alexander, Kettenberger, Hubert, Liedl, Klaus R.
Published in Frontiers in immunology (10.08.2021)
Published in Frontiers in immunology (10.08.2021)
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Journal Article
VH-VL orientation prediction for antibody humanization candidate selection: A case study
Bujotzek, Alexander, Lipsmeier, Florian, Harris, Seth F, Benz, Jörg, Kuglstatter, Andreas, Georges, Guy
Published in mAbs (01.01.2016)
Published in mAbs (01.01.2016)
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Journal Article
Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime
Moll, Solange, Yasui, Yukari, Abed, Ahmed, Murata, Takeshi, Shimada, Hideaki, Maeda, Akira, Fukushima, Naoshi, Kanamori, Masakazu, Uhles, Sabine, Badi, Laura, Cagarelli, Thomas, Formentini, Ivan, Drawnel, Faye, Georges, Guy, Bergauer, Tobias, Gasser, Rodolfo, Bonfil, R Daniel, Fridman, Rafael, Richter, Hans, Funk, Juergen, Moeller, Marcus J, Chatziantoniou, Christos, Prunotto, Marco
Published in Journal of translational medicine (01.06.2018)
Published in Journal of translational medicine (01.06.2018)
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Journal Article
Phthalazinone Pyrazoles as Potent, Selective, and Orally Bioavailable Inhibitors of Aurora-A Kinase
Prime, Michael E, Courtney, Stephen M, Brookfield, Frederick A, Marston, Richard W, Walker, Victoria, Warne, Justin, Boyd, Andrew E, Kairies, Norman A, von der Saal, Wolfgang, Limberg, Anja, Georges, Guy, Engh, Richard A, Goller, Bernhard, Rueger, Petra, Rueth, Matthias
Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
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