Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities
Cho, Steven X., Rudloff, Ina, Lao, Jason C., Pang, Merrin A., Goldberg, Rimma, Bui, Christine B., McLean, Catriona A., Stock, Magdalena, Klassert, Tilman E., Slevogt, Hortense, Mangan, Niamh E., Cheng, Wei, Fischer, Doris, Gfroerer, Stefan, Sandhu, Manjeet K., Ngo, Devi, Bujotzek, Alexander, Lariviere, Laurent, Schumacher, Felix, Tiefenthaler, Georg, Beker, Friederike, Collins, Clare, Kamlin, C. Omar F., König, Kai, Malhotra, Atul, Tan, Kenneth, Theda, Christiane, Veldman, Alex, Ellisdon, Andrew M., Whisstock, James C., Berger, Philip J., Nold-Petry, Claudia A., Nold, Marcel F.
Published in Nature communications (13.11.2020)
Published in Nature communications (13.11.2020)
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Brain Shuttle Antibody for Alzheimer’s Disease with Attenuated Peripheral Effector Function due to an Inverted Binding Mode
Weber, Felix, Bohrmann, Bernd, Niewoehner, Jens, Fischer, Jens A.A., Rueger, Petra, Tiefenthaler, Georg, Moelleken, Joerg, Bujotzek, Alexander, Brady, Kevin, Singer, Thomas, Ebeling, Martin, Iglesias, Antonio, Freskgård, Per-Ola
Published in Cell reports (Cambridge) (02.01.2018)
Published in Cell reports (Cambridge) (02.01.2018)
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A robust high throughput platform to generate functional recombinant monoclonal antibodies using rabbit B cells from peripheral blood
Seeber, Stefan, Ros, Francesca, Thorey, Irmgard, Tiefenthaler, Georg, Kaluza, Klaus, Lifke, Valeria, Fischer, Jens André Alexander, Klostermann, Stefan, Endl, Josef, Kopetzki, Erhard, Pashine, Achal, Siewe, Basile, Kaluza, Brigitte, Platzer, Josef, Offner, Sonja
Published in PloS one (04.02.2014)
Published in PloS one (04.02.2014)
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Candidate Biomarkers of Response to an Experimental Cancer Drug Identified through a Large-scale RNA Interference Genetic Screen
MULLENDERS, Jasper, VON DER SAAL, Wolfgang, VAN DONGEN, Miranda M. W, REIFF, Ulrike, VAN WILLIGEN, Rogier, BEIJERSBERGEN, Roderick L, TIEFENTHALER, Georg, KLEIN, Christian, BERNARDS, René
Published in Clinical cancer research (15.09.2009)
Published in Clinical cancer research (15.09.2009)
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Potential of Protein-based Anti-metastatic Therapy with Serpins and Inter α-Trypsin Inhibitors
Weidle, Ulrich H, Birzele, Fabian, Tiefenthaler, Georg
Published in Cancer genomics & proteomics (01.07.2018)
Published in Cancer genomics & proteomics (01.07.2018)
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Proteases as activators for cytotoxic prodrugs in antitumor therapy
Weidle, Ulrich H, Tiefenthaler, Georg, Georges, Guy
Published in Cancer genomics & proteomics (01.03.2014)
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Published in Cancer genomics & proteomics (01.03.2014)
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The emerging role of new protein scaffold-based agents for treatment of cancer
Weidle, Ulrich H, Auer, Johannes, Brinkmann, Ulrich, Georges, Guy, Tiefenthaler, Georg
Published in Cancer genomics & proteomics (01.07.2013)
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Published in Cancer genomics & proteomics (01.07.2013)
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Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential
Bujotzek, Alexander, Tiefenthaler, Georg, Lariviere, Laurent, D’Andrea, Laura, Marquez, Elsa A., Rudloff, Ina, Cho, Steven X., Deen, Nadia S., Richter, Wolfgang, Regenass-Lechner, Franziska, Poehler, Alexander, Whisstock, James C., Sydow-Andersen, Jasmin, Reiser, Xaver, Schuster, Sabine, Neubauer, Jeannette, Hoepfl, Sebastian, Richter, Kirsten, Nold, Marcel F., Nold-Petry, Claudia A., Schumacher, Felix, Ellisdon, Andrew M.
Published in Cell chemical biology (21.04.2022)
Published in Cell chemical biology (21.04.2022)
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Journal Article
MULTISPECIFIC ANTIBODIES AND USE THEREOF
SEBASTIAN FENN, JOERG MOELLEKEN, GEORG TIEFENTHALER, STEFAN KLOSTERMANN, ALEXANDER BUJOTZEK, MEHER MAJETY, JENS FISCHER, CLAUDIA KIRSTENPFAD, SILKE KIRCHNER, STEFAN DENGL
Year of Publication 13.06.2023
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Year of Publication 13.06.2023
Patent
ANTI-HLA-G ANTIBODIES AND USE THEREOF
CARINA HAGE, CHRISTIANE NEUMANN, GEORG TIEFENTHALER, ALEXANDER BUJOTZEK, ANNE FREIMOSER-GRUNDSCHOBER, MEHER MAJETY, CHRISTIAN SPICK, SILKE KIRCHNER, ALEJANDRO CARPY GUTIERREZ CIRLOS, THOMAS WEINDL, MOESSNER EKKEHARD, THOMAS HOFER
Year of Publication 24.10.2023
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Year of Publication 24.10.2023
Patent
Targeted delivery of interferon-α to hepatitis B virus-infected cells using T-cell receptor-like antibodies
Ji, Changhua, Sastry, Konduru S.R., Tiefenthaler, Georg, Cano, Jennifer, Tang, Tenny, Ho, Zi Zong, Teoh, Denise, Bohini, Sandhya, Chen, Antony, Sankuratri, Surya, Macary, Paul A., Kennedy, Patrick, Ma, Han, Ries, Stefan, Klumpp, Klaus, Kopetzki, Erhard, Bertoletti, Antonio
Published in Hepatology (Baltimore, Md.) (01.12.2012)
Published in Hepatology (Baltimore, Md.) (01.12.2012)
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BISPECIFIC ANTI-CCL2 ANTIBODIES
JOERG MOELLEKEN, RUNYI ADELINE LAM, GAN SIOK WAN, ADRIAN WEI SHIONG HO, HUBERT KETTENBERGER, MARTIN SCHAEFER, VALERIA RUNZA, MARIA VIERT, FENG SHU, ANTON JOCHNER, GEORG TIEFENTHALER, GREGOR JORDAN, TILMAN SCHLOTHAUER, MEHER MAJETY, JENS FISCHER, GUY GEORGES, MICHAEL GERTZ
Year of Publication 10.04.2024
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Year of Publication 10.04.2024
Patent
TCR-MHC/peptide interaction: prospects for new anti-tumoral agents
Weidle, Ulrich H, Georges, Guy, Tiefenthaler, Georg
Published in Cancer genomics & proteomics (01.11.2014)
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Published in Cancer genomics & proteomics (01.11.2014)
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The intriguing options of multispecific antibody formats for treatment of cancer
Weidle, Ulrich H, Tiefenthaler, Georg, Weiss, Elisabeth H, Georges, Guy, Brinkmann, Ulrich
Published in Cancer genomics & proteomics (01.01.2013)
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Published in Cancer genomics & proteomics (01.01.2013)
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BLOOD-BRAIN BARRIER SHUTTLES CONTAINING ANTIBODIES RECOGNIZING α-SYNUCLEIN
GEORG TIEFENTHALER, WAGNER ZAGO, OLAF MUNDIGL, TARLOCHAN S NIIJAR, JENS NIEWOEHNER, ROBIN BARBOUR, KATE DORA GAMES-THIEL
Year of Publication 10.12.2020
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Year of Publication 10.12.2020
Patent
RAPID METHODS FOR CLONING AND EXPRESSING ANTIBODY VARIABLE REGION GENE SEGMENTS OF THE SAME ORIGIN
STEFAN SEEBER, GEORG TIEFENTHALER, ERHARD KOPETZKI, DOMINIQUE OSTLER, SIMONE HOEGE
Year of Publication 21.12.2017
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Year of Publication 21.12.2017
Patent
Development of Bispecific Molecules for the In Situ Detection of Protein-Protein Interactions and Protein Phosphorylation
van Dieck, Jan, Schmid, Volker, Heindl, Dieter, Dziadek, Sebastian, Schraeml, Michael, Gerg, Michael, Massoner, Petra, Engel, Alfred M., Tiefenthaler, Georg, Vural, Serhat, Stritt, Simon, Tetzlaff, Fabian, Soukupova, Monika, Kopetzki, Erhard, Bossenmaier, Birgit, Thomas, Marlene, Klein, Christian, Mertens, Alfred, Heller, Astrid, Tacke, Michael
Published in Chemistry & biology (20.03.2014)
Published in Chemistry & biology (20.03.2014)
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