Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
Liu, Feifei, Yang, Xiaotong, Geng, Meiyu, Huang, Min
Published in Acta pharmaceutica Sinica. B (01.07.2018)
Published in Acta pharmaceutica Sinica. B (01.07.2018)
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Journal Article
Molecularly targeted cancer therapy: some lessons from the past decade
Huang, Min, Shen, Aijun, Ding, Jian, Geng, Meiyu
Published in Trends in pharmacological sciences (Regular ed.) (01.01.2014)
Published in Trends in pharmacological sciences (Regular ed.) (01.01.2014)
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Journal Article
Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression
Wang, Xinyi, Sun, Guangqiang, Feng, Teng, Zhang, Jing, Huang, Xun, Wang, Tao, Xie, Zuoquan, Chu, Xingkun, Yang, Jun, Wang, Huan, Chang, Shuaishuai, Gong, Yanxue, Ruan, Lingfei, Zhang, Guanqun, Yan, Siyuan, Lian, Wen, Du, Chen, Yang, Dabing, Zhang, Qingli, Lin, Feifei, Liu, Jia, Zhang, Haiyan, Ge, Changrong, Xiao, Shifu, Ding, Jian, Geng, Meiyu
Published in Cell research (01.10.2019)
Published in Cell research (01.10.2019)
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Journal Article
Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase
Dai, Xiaoyang, Yan, Juan, Fu, Xuhong, Pan, Qiuming, Sun, Danni, Xu, Yuan, Wang, Jiang, Nie, Litong, Tong, Linjiang, Shen, Aijun, Zheng, Mingyue, Huang, Min, Tan, Minjia, Liu, Hong, Huang, Xun, Ding, Jian, Geng, Meiyu
Published in Clinical cancer research (15.10.2017)
Published in Clinical cancer research (15.10.2017)
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Journal Article
Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation
Lian, Qiaoshi, Xu, Jun, Yan, Shanshan, Huang, Min, Ding, Honghua, Sun, Xiaoyu, Bi, Aiwei, Ding, Jian, Sun, Bing, Geng, Meiyu
Published in Cell research (01.06.2017)
Published in Cell research (01.06.2017)
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Journal Article
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors
Huang, Xun, Yan, Juan, Zhang, Min, Wang, Yafang, Chen, Yi, Fu, Xuhong, Wei, Rongrui, Zheng, Xing-ling, Liu, Zhiwei, Zhang, Xiong, Yang, Hong, Hao, Bingbing, Shen, Yan-yan, Su, Yi, Cong, Xiaoji, Huang, Min, Tan, Minjia, Ding, Jian, Geng, Meiyu
Published in Cell (20.09.2018)
Published in Cell (20.09.2018)
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Journal Article
Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies
Liang, Xuewu, Zang, Jie, Li, Xiaoyang, Tang, Shuai, Huang, Min, Geng, Meiyu, Chou, C. James, Li, Chunpu, Cao, Yichun, Xu, Wenfang, Liu, Hong, Zhang, Yingjie
Published in Journal of medicinal chemistry (25.04.2019)
Published in Journal of medicinal chemistry (25.04.2019)
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Journal Article
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer
Jin, Nan, Bi, Aiwei, Lan, Xiaojing, Xu, Jun, Wang, Xiaomin, Liu, Yingluo, Wang, Ting, Tang, Shuai, Zeng, Hanlin, Chen, Ziqi, Tan, Minjia, Ai, Jing, Xie, Hua, Zhang, Tao, Liu, Dandan, Huang, Ruimin, Song, Yue, Leung, Elaine Lai-Han, Yao, Xiaojun, Ding, Jian, Geng, Meiyu, Lin, Shu-Hai, Huang, Min
Published in Nature communications (20.06.2019)
Published in Nature communications (20.06.2019)
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Journal Article
p53 β-hydroxybutyrylation attenuates p53 activity
Liu, Kun, Li, Fangzhou, Sun, Qianqian, Lin, Ning, Han, Haichao, You, Kaiqiang, Tian, Feng, Mao, Zebin, Li, Tingting, Tong, Tanjun, Geng, Meiyu, Zhao, Yingming, Gu, Wei, Zhao, Wenhui
Published in Cell death & disease (11.03.2019)
Published in Cell death & disease (11.03.2019)
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Journal Article
Development of a novel lactate dehydrogenase A inhibitor with potent antitumor activity and immune activation
Du, Mengyan, Yu, Ting, Zhan, Qinjinge, Li, Han, Zou, Yiping, Geng, Meiyu, Meng, Tao, Xie, Zuoquan
Published in Cancer science (01.09.2022)
Published in Cancer science (01.09.2022)
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Journal Article
Chronic Kidney Disease and Cognitive Impairment: The Kidney-Brain Axis
Xie, Zuoquan, Tong, Siyu, Chu, Xingkun, Feng, Teng, Geng, Meiyu
Published in Kidney diseases (01.07.2022)
Published in Kidney diseases (01.07.2022)
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Journal Article
Discovery of Potent Irreversible Pan-Fibroblast Growth Factor Receptor (FGFR) Inhibitors
Wang, Yuming, Li, Lijun, Fan, Jun, Dai, Yang, Jiang, Alan, Geng, Meiyu, Ai, Jing, Duan, Wenhu
Published in Journal of medicinal chemistry (25.10.2018)
Published in Journal of medicinal chemistry (25.10.2018)
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Journal Article
GV-971 prevents severe acute pancreatitis by remodeling the microbiota-metabolic-immune axis
Chen, Xi, Chen, Xin, Yan, Ding, Zhang, Na, Fu, Wen, Wu, Meixuan, Ge, Feifei, Wang, Jiangtuan, Li, Xiaofen, Geng, Meiyu, Wang, Jinheng, Tang, Daolin, Liu, Jinbao
Published in Nature communications (27.09.2024)
Published in Nature communications (27.09.2024)
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Journal Article
Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models
Ai, Jing, Chen, Yi, Peng, Xia, Ji, Yinchun, Xi, Yong, Shen, Yanyan, Yang, Xinying, Su, Yi, Sun, Yiming, Gao, Yinglei, Ma, Yuchi, Xiong, Bing, Shen, Jingkang, Ding, Jian, Geng, Meiyu
Published in Molecular cancer therapeutics (01.04.2018)
Published in Molecular cancer therapeutics (01.04.2018)
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Journal Article
Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells
Qu, Jia, Sun, Wenyi, Zhong, Jie, Lv, Hao, Zhu, Mingrui, Xu, Jun, Jin, Nan, Xie, Zuoquan, Tan, Minjia, Lin, Shu-Hai, Geng, Meiyu, Ding, Jian, Huang, Min
Published in The Journal of cell biology (01.02.2017)
Published in The Journal of cell biology (01.02.2017)
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Journal Article
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
Zhang, Tao, Qu, Rong, Chan, Shingpan, Lai, Mengzhen, Tong, Linjiang, Feng, Fang, Chen, Hongyu, Song, Tingting, Song, Peiran, Bai, Gang, Liu, Yingqiang, Wang, Yanan, Li, Yan, Su, Yi, Shen, Yanyan, Sun, Yiming, Chen, Yi, Geng, Meiyu, Ding, Ke, Ding, Jian, Xie, Hua
Published in Molecular cancer (13.05.2020)
Published in Molecular cancer (13.05.2020)
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Journal Article
c-Myc Alteration Determines the Therapeutic Response to FGFR Inhibitors
Liu, Hongyan, Ai, Jing, Shen, Aijun, Chen, Yi, Wang, Xinyi, Peng, Xia, Chen, Hui, Shen, Yanyan, Huang, Min, Ding, Jian, Geng, Meiyu
Published in Clinical cancer research (15.02.2017)
Published in Clinical cancer research (15.02.2017)
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Journal Article
LS‐106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
Liu, Yingqiang, Lai, Mengzhen, Li, Shan, Wang, Yanan, Feng, Fang, Zhang, Tao, Tong, Linjiang, Zhang, Mengge, Chen, Hao, Chen, Yi, Song, Peiran, Li, Yan, Bai, Gang, Ning, Yi, Tang, Haotian, Fang, Yan, Chen, Yi, Lu, Xiaoyun, Geng, Meiyu, Ding, Ke, Yu, Ker, Xie, Hua, Ding, Jian
Published in Cancer science (01.02.2022)
Published in Cancer science (01.02.2022)
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Journal Article
Down-regulation of G9a triggers DNA damage response and inhibits colorectal cancer cells proliferation
Zhang, Jie, He, Pengxing, Xi, Yong, Geng, Meiyu, Chen, Yi, Ding, Jian
Published in Oncotarget (20.02.2015)
Published in Oncotarget (20.02.2015)
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