Search Results - "GENG Meiyu" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy

Structure-Based Discovery of Potent CARM1 Inhibitors for Solid Tumor and Cancer Immunology Therapy

by Zhang, Zhuqing, Guo, Zuhao, Xu, Xiaowei, Cao, Danyan, Yang, Hong, Li, Yanlian, Shi, Qiongyu, Du, Zhiyan, Guo, Xiaobin, Wang, Xin, Chen, Danqi, Zhang, Ying, Chen, Lin, Zhou, Kaixin, Li, Jian, Geng, Meiyu, Huang, Xun, Xiong, Bing
Published in Journal of medicinal chemistry (25.11.2021)

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Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors

Structure-based discovery of a new series of nucleoside-derived ring-opening PRMT5 inhibitors

by Chen, Yuting, Wang, Zekun, Zhang, Junjie, Shi, Qiongyu, Yang, Hong, Deng, Yue, Wang, Xingcan, Liu, Tongchao, Geng, Meiyu, Xiong, Bing, Huang, Xun
Published in European journal of medicinal chemistry (05.03.2024)

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Structure−Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists

Structure−Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists

by Shen, Ancheng, Li, Xiyuan, Zhang, Yan, Ma, Jing, Xiao, Ruoxuan, Wang, Xiyuan, Song, Zilan, Liu, Zhiguo, Geng, Meiyu, Zhang, Ao, Xie, Zuoquan, Ding, Chunyong
Published in European journal of medicinal chemistry (05.11.2022)

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Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder

Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder

by Xie, Zuoquan, Huang, Jingjing, Sun, Guangqiang, He, Shen, Luo, Zhiyu, Zhang, Linna, Li, Liang, Yao, Min, Du, Chen, Yu, Wenjuan, Feng, Yuan, Yang, Dabing, Zhang, Jing, Ge, Changrong, Li, Huafang, Geng, Meiyu
Published in Psychiatry research (01.04.2024)

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Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer

Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer

by Gai, Xiameng, Liu, Yingluo, Lan, Xiaojing, Chen, Luoyi, Yuan, Tao, Xu, Jun, Li, Yize, Zheng, Ying, Yan, Yiyang, Yang, Liya, Fu, Yixian, Tang, Shuai, Cao, Siyuwei, Dai, Xiaoyang, Zhu, Hong, Geng, Meiyu, Ding, Jian, Pu, Congying, Huang, Min
Published in Cancer research (Chicago, Ill.) (14.06.2024)

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Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors

Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors

by Tang, Mingze, Zhou, Xuan, Shen, Qianqian, Fang, Chen, Peng, Xia, Ji, Yinchun, Zhu, Guijun, Geng, Meiyu, Chen, Yi, Duan, Wenhu, Ai, Jing, Zhang, Hefeng
Published in Journal of molecular structure (15.12.2024)

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Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration

Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration

by Niu, Jing, Bai, Hudagula, Li, Zizhou, Gao, Yuzhe, Zhang, Yan, Wang, Xiyuan, Yang, Yaxi, Xu, Yungen, Geng, Meiyu, Xie, Zuoquan, Zhou, Bing
Published in European journal of medicinal chemistry (05.08.2022)

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Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration

Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration

by Niu, Jing, Bai, Hudagula, Li, Zizhou, Gao, Yuzhe, Zhang, Yan, Wang, Xiyuan, Yang, Yaxi, Xu, Yungen, Geng, Meiyu, Xie, Zuoquan, Zhou, Bing
Published in European journal of medicinal chemistry (05.08.2022)

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Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs

Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs

by Geng, Kaijun, Liu, Hongchun, Song, Zilan, Zhang, Chi, Zhang, Minmin, Yang, Hong, Cao, Jingchen, Geng, Meiyu, Shen, Aijun, Zhang, Ao
Published in European journal of medicinal chemistry (25.05.2018)

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Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRASG12C inhibitors

Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRASG12C inhibitors

by Xiao, Xuanzheng, Lai, Mengzhen, Song, Zilan, Geng, Meiyu, Ding, Jian, Xie, Hua, Zhang, Ao
Published in European journal of medicinal chemistry (05.03.2021)

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Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold

Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold

by Chen, Jingjing, He, Huixin, Wei, Aihuan, Li, Yalei, Cheng, Gang, Qin, Hui, Zhong, Hanyue, Liu, Hongchun, Geng, Meiyu, Shen, Aijun, Hu, Youhong
Published in European journal of medicinal chemistry (05.06.2022)

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Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase

Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase

by Sun, Yaoliang, Zhang, Ying, Chen, Xiaoai, Yu, Aisong, Du, Wenhao, Huang, Yuting, Wu, Feifei, Yu, Lei, Li, Jiayi, Wen, Cuiyun, Yang, Hong, Shi, Qiongyu, Geng, Meiyu, Huang, Xun, Xu, Shilin
Published in European journal of medicinal chemistry (05.09.2022)

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Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold

Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold

by Liu, Jian, Peng, Xia, Dai, Yang, Zhang, Wei, Ren, Sumei, Ai, Jing, Geng, Meiyu, Li, Yingxia
Published in Organic & biomolecular chemistry (28.07.2015)

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Identification and Therapeutic Intervention of Coactivated Anaplastic Lymphoma Kinase, Fibroblast Growth Factor Receptor 2, and Ephrin Type‐A Receptor 5 Kinases in Hepatocellular Carcinoma

Identification and Therapeutic Intervention of Coactivated Anaplastic Lymphoma Kinase, Fibroblast Growth Factor Receptor 2, and Ephrin Type‐A Receptor 5 Kinases in Hepatocellular Carcinoma

by Wang, Xin, Zhang, Minmin, Ping, Fangfang, Liu, Hongchun, Sun, Jingya, Wang, Yueqin, Shen, Aijun, Ding, Jian, Geng, Meiyu
Published in Hepatology (Baltimore, Md.) (01.02.2019)

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Discovery of 3‑(5′-Substituted)-Benzimidazole-5-(1-(3,5-dichloropyridin-4-yl)ethoxy)‑1H‑indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors: Design, Synthesis, and Biological Evaluation

Discovery of 3‑(5′-Substituted)-Benzimidazole-5-(1-(3,5-dichloropyridin-4-yl)ethoxy)‑1H‑indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors: Design, Synthesis, and Biological Evaluation

by Yan, Wei, Wang, Xinyi, Dai, Yang, Zhao, Bin, Yang, Xinying, Fan, Jun, Gao, Yinglei, Meng, Fanwang, Wang, Yuming, Luo, Cheng, Ai, Jing, Geng, Meiyu, Duan, Wenhu
Published in Journal of medicinal chemistry (28.07.2016)

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Prenylated Indole Diketopiperazines from the Marine-Derived Fungus Aspergillus versicolor

Prenylated Indole Diketopiperazines from the Marine-Derived Fungus Aspergillus versicolor

by Peng, Jixing, Gao, Huquan, Li, Jing, Ai, Jing, Geng, Meiyu, Zhang, Guojian, Zhu, Tianjiao, Gu, Qianqun, Li, Dehai
Published in Journal of organic chemistry (05.09.2014)

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Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors

Structure-Based Discovery of a Series of NSD2-PWWP1 Inhibitors

by Li, Na, Yang, Hong, Liu, Ke, Zhou, Liwei, Huang, Yuting, Cao, Danyan, Li, Yanlian, Sun, Yaoliang, Yu, Aisong, Du, Zhiyan, Yu, Feng, Zhang, Ying, Wang, Bingyang, Geng, Meiyu, Li, Jian, Xiong, Bing, Xu, Shilin, Huang, Xun, Liu, Tongchao
Published in Journal of medicinal chemistry (14.07.2022)

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Dicarabrones A and B, a Pair of New Epimers Dimerized from Sesquiterpene Lactones via a [3 + 2] Cycloaddition from Carpesium abrotanoides

Dicarabrones A and B, a Pair of New Epimers Dimerized from Sesquiterpene Lactones via a [3 + 2] Cycloaddition from Carpesium abrotanoides

by Wu, Jiewei, Tang, Chunping, Chen, Lan, Qiao, Yan, Geng, Meiyu, Ye, Yang
Published in Organic letters (03.04.2015)

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Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors

Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors

by Li, Chunpu, Dai, Yang, Kong, Xiangtai, Wang, Bao, Peng, Xia, Wu, Hengbo, Shen, Yanyan, Yang, Yanchen, Ji, Yinchun, Wang, Danyi, Li, Shuangjie, Li, Xutong, Shi, Yuqiang, Geng, Meiyu, Zheng, Mingyue, Ai, Jing, Liu, Hong
Published in Journal of medicinal chemistry (09.03.2023)

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Synthesis and antitumor activities of naturally occurring oleanolic acid triterpenoid saponins and their derivatives

Synthesis and antitumor activities of naturally occurring oleanolic acid triterpenoid saponins and their derivatives

by Liu, Qingchao, Liu, Hongchun, Zhang, Lei, Guo, Tiantian, Wang, Peng, Geng, Meiyu, Li, Yingxia
Published in European journal of medicinal chemistry (01.06.2013)

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