A Novel Investigational Fc-Modified Humanized Monoclonal Antibody, Motavizumab-YTE, Has an Extended Half-Life in Healthy Adults
ROBBIE, Gabriel J, CRISTE, Ryan, DALL'ACQUA, William F, JENSEN, Kathryn, PATEL, Nita K, LOSONSKY, Genevieve A, GRIFFIN, M. Pamela
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
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Population Pharmacokinetics of Palivizumab, a Humanized Anti-Respiratory Syncytial Virus Monoclonal Antibody, in Adults and Children
Robbie, Gabriel J, Zhao, Liang, Mondick, John, Losonsky, Genevieve, Roskos, Lorin K
Published in Antimicrobial Agents and Chemotherapy (01.09.2012)
Published in Antimicrobial Agents and Chemotherapy (01.09.2012)
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Efficacy of motavizumab for the prevention of respiratory syncytial virus disease in healthy Native American infants: a phase 3 randomised double-blind placebo-controlled trial
O'Brien, Katherine L, Prof, Chandran, Aruna, MD, Weatherholtz, Robert, BS, Jafri, Hasan S, MD, Griffin, M Pamela, MD, Bellamy, Terramika, MS, Millar, Eugene V, PhD, Jensen, Kathryn M, MS, Harris, Brian S, MS, Reid, Raymond, MD, Moulton, Lawrence H, PhD, Losonsky, Genevieve A, Karron, Ruth A, Prof, Santosham, Mathuram, Prof
Published in The Lancet infectious diseases (01.12.2015)
Published in The Lancet infectious diseases (01.12.2015)
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Motavizumab for prophylaxis of respiratory syncytial virus in high-risk children: a noninferiority trial
Carbonell-Estrany, Xavier, Simões, Eric A F, Dagan, Ron, Hall, Caroline B, Harris, Brian, Hultquist, Micki, Connor, Edward M, Losonsky, Genevieve A
Published in Pediatrics (Evanston) (01.01.2010)
Published in Pediatrics (Evanston) (01.01.2010)
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Analysis of Respiratory Syncytial Virus Preclinical and Clinical Variants Resistant to Neutralization by Monoclonal Antibodies Palivizumab and/or Motavizumab
Zhu, Qing, McAuliffe, Josie M., Patel, Nita K., Palmer-Hill, Frances J., Yang, Chin-fen, Liang, Brandon, Su, Lan, Zhu, Wei, Wachter, Leslie, Wilson, Susan, MacGill, Randall S., Krishnan, Subramaniam, McCarthy, Michael P., Losonsky, Genevieve A., Suzich, JoAnn A.
Published in The Journal of infectious diseases (01.03.2011)
Published in The Journal of infectious diseases (01.03.2011)
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Motavizumab treatment of infants hospitalized with respiratory syncytial virus infection does not decrease viral load or severity of illness
Ramilo, Octavio, Lagos, Rosanna, Sáez-Llorens, Xavier, Suzich, JoAnn, Wang, C Kathy, Jensen, Kathryn M, Harris, Brian S, Losonsky, Genevieve A, Griffin, M Pamela
Published in The Pediatric infectious disease journal (01.07.2014)
Published in The Pediatric infectious disease journal (01.07.2014)
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A Randomized Controlled Trial of Motavizumab Versus Palivizumab for the Prophylaxis of Serious Respiratory Syncytial Virus Disease in Children With Hemodynamically Significant Congenital Heart Disease
Feltes, Timothy F, Sondheimer, Henry M, Tulloh, Robert M R, Harris, Brian S, Jensen, Kathryn M, Losonsky, Genevieve A, Griffin, M Pamela
Published in Pediatric research (01.08.2011)
Published in Pediatric research (01.08.2011)
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A phase 2, randomized, double-blind safety and pharmacokinetic assessment of respiratory syncytial virus (RSV) prophylaxis with motavizumab and palivizumab administered in the same season
Fernández, Pilar, Trenholme, Adrian, Abarca, Katia, Griffin, M Pamela, Hultquist, Micki, Harris, Brian, Losonsky, Genevieve A
Published in BMC pediatrics (03.06.2010)
Published in BMC pediatrics (03.06.2010)
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Safety, tolerability, pharmacokinetics, and immunogenicity of motavizumab, a humanized, enhanced-potency monoclonal antibody for the prevention of respiratory syncytial virus infection in at-risk children
Abarca, Katia, Jung, Elizabeth, Fernández, Pilar, Zhao, Liang, Harris, Brian, Connor, Edward M, Losonsky, Genevieve A
Published in The Pediatric infectious disease journal (01.04.2009)
Published in The Pediatric infectious disease journal (01.04.2009)
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Safety and antiviral activity of motavizumab, a respiratory syncytial virus (RSV)-specific humanized monoclonal antibody, when administered to RSV-infected children
Lagos, Rosanna, DeVincenzo, John P, Muñoz, Alma, Hultquist, Micki, Suzich, Joann, Connor, Edward M, Losonsky, Genevieve A
Published in The Pediatric infectious disease journal (01.09.2009)
Published in The Pediatric infectious disease journal (01.09.2009)
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Development of a PIV-vectored RSV vaccine: Preclinical evaluation of safety, toxicity, and enhanced disease and initial clinical testing in healthy adults
Tang, Roderick S, Spaete, Richard R, Thompson, Mark W, MacPhail, Mia, Guzzetta, Jeanne M, Ryan, Patricia C, Reisinger, Keith, Chandler, Patricia, Hilty, Milo, Walker, Robert E, Gomez, Margarita M, Losonsky, Genevieve A
Published in Vaccine (25.11.2008)
Published in Vaccine (25.11.2008)
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Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato
Tacket, C O, Mason, H S, Losonsky, G, Clements, J D, Levine, M M, Arntzen, C J
Published in Nature medicine (01.05.1998)
Published in Nature medicine (01.05.1998)
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Safety and immunogenicity of oral inactivated whole-cell Helicobacter pylori vaccine with adjuvant among volunteers with or without subclinical infection
KOTLOFF, Karen L, SZTEIN, Marcelo B, WASSERMAN, Steven S, LOSONSKY, Genevieve A, DILORENZO, Susan C, WALKER, Richard I
Published in Infection and immunity (01.06.2001)
Published in Infection and immunity (01.06.2001)
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Prevalence and Characteristics of Human Metapneumovirus Infection Among Hospitalized Children at High Risk for Severe Lower Respiratory Tract Infection
Anderson, Evan J., Simões, Eric A. F., Buttery, Jim P., Dennehy, Penelope H., Domachowske, Joseph B., Jensen, Kathryn, Lieberman, Jay M., Losonsky, Genevieve A., Yogev, Ram
Published in Journal of the Pediatric Infectious Diseases Society (01.09.2012)
Published in Journal of the Pediatric Infectious Diseases Society (01.09.2012)
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Randomized, Double-Blind Study of the Pharmacokinetics and Safety of Palivizumab Liquid Formulation Compared with Lyophilized Formulation
Robbie, Gabriel J., Makari, Doris, Harris, Brian, Losonsky, Genevieve A., Jafri, Hasan S.
Published in Infectious diseases and therapy (01.12.2014)
Published in Infectious diseases and therapy (01.12.2014)
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Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults
KOTLOFF, Karen L, WASSERMAN, Steven S, LOSONSKY, Genevieve A, THOMAS, William JR, NICHOLS, Richard, EDELMAN, Robert, BRIDWELL, Margaret, MONATH, Thomas P
Published in Infection and immunity (01.02.2001)
Published in Infection and immunity (01.02.2001)
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Phase I Evaluation of ΔvirG Shigella sonnei Live, Attenuated, Oral Vaccine Strain WRSS1 in Healthy Adults
KOTLOFF, Karen L, TAYLOR, David N, CAMPBELL, James D, LEVINE, Myron M, HALE, Thomas L, SZTEIN, Marcelo B, WASSERMAN, Steven S, LOSONSKY, Genevieve A, NATARO, James P, VENKATESAN, Malabi, HARTMAN, Antoinette, PICKING, William D, KATZ, David E
Published in Infection and Immunity (01.04.2002)
Published in Infection and Immunity (01.04.2002)
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Randomized, Double-Blind, Placebo-Controlled, Multicentered Trial of the Efficacy of a Single Dose of Live Oral Cholera Vaccine CVD 103-HgR in Preventing Cholera following Challenge with Vibrio cholerae O1 El Tor Inaba Three Months after Vaccination
TACKET, C. O, COHEN, M. B, SCHIFF, G, LEVINE, M. M, WASSERMAN, S. S, LOSONSKY, G, LIVIO, S, KOTLOFF, K, EDELMAN, R, KAPER, J. B, CRYZ, S. J, GIANNELLA, R. A
Published in Infection and Immunity (01.12.1999)
Published in Infection and Immunity (01.12.1999)
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Attenuated Salmonella enterica Serovar Typhi and Shigella flexneri 2a Strains Mucosally Deliver DNA Vaccines Encoding Measles Virus Hemagglutinin, Inducing Specific Immune Responses and Protection in Cotton Rats
Pasetti, Marcela F., Barry, Eileen M., Losonsky, Genevieve, Singh, Mahender, Medina-Moreno, Sandra M., Polo, John M., Ulmer, Jeffrey, Robinson, Harriet, Sztein, Marcelo B., Levine, Myron M.
Published in Journal of Virology (01.05.2003)
Published in Journal of Virology (01.05.2003)
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