Parallel mechanochemical optimization - Buchwald-Hartwig C-N coupling as a test case
Lemesre, Quentin, Wiesner, Thomas, Wiechert, Rainer, Rodrigo, Eduardo, Triebel, Sonja, Geneste, Hervé
Published in Green chemistry : an international journal and green chemistry resource : GC (18.07.2022)
Published in Green chemistry : an international journal and green chemistry resource : GC (18.07.2022)
Get full text
Journal Article
Investigation of Mechanochemical Sonogashira CouplingsFrom Batch Solution to Continuous Reactive Extrusion through Ball-Milling Optimization
Hastings, Riley H., Mokhtar, Mennatullah M., Ruggles, Alexander, Schmidt, Constanze, Bourdeau, David, Haibach, Michael C., Geneste, Hervé, Mack, James, Co, Sarah S., Speight, Isaiah R.
Published in Organic process research & development (15.09.2023)
Published in Organic process research & development (15.09.2023)
Get full text
Journal Article
Novel, potent, selective and brain penetrant vasopressin 1b receptor antagonists
Geneste, Hervé, Bhowmik, Swati, van Gaalen, Marcel M., Hornberger, Wilfried, Hutchins, Charles W., Netz, Astrid, Oost, Thorsten, Unger, Liliane
Published in Bioorganic & medicinal chemistry letters (15.10.2018)
Published in Bioorganic & medicinal chemistry letters (15.10.2018)
Get full text
Journal Article
Multi-faceted reactivity of N -fluorobenzenesulfonimide (NFSI) under mechanochemical conditions: fluorination, fluorodemethylation, sulfonylation, and amidation reactions
Hernández, José G, Ardila-Fierro, Karen J, Barišić, Dajana, Geneste, Hervé
Published in Beilstein journal of organic chemistry (2022)
Published in Beilstein journal of organic chemistry (2022)
Get full text
Journal Article
Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic properties
Oost, Thorsten, Backfisch, Gisela, Bhowmik, Swati, van Gaalen, Marcel M., Geneste, Hervé, Hornberger, Wilfried, Lubisch, Wilfried, Netz, Astrid, Unger, Liliane, Wernet, Wolfgang
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
Get full text
Journal Article
LY-2140023, a prodrug of the group II metabotropic glutamate receptor agonist LY-404039 for the potential treatment of schizophrenia
Mezler, Mario, Geneste, Hervé, Gault, Laura, Marek, Gerard J
Published in Current opinion in investigational drugs (London, England : 2000) (01.07.2010)
Get more information
Published in Current opinion in investigational drugs (London, England : 2000) (01.07.2010)
Journal Article
Investigation of Mechanochemical Thianthrene-Mediated Aryl C−H Functionalization
Vugrin, Leonarda, Cvrtila, Ivica, Geneste, Hervé, Halasz, Ivan
Published in Croatica Chemica Acta (2024)
Published in Croatica Chemica Acta (2024)
Get full text
Journal Article
Paper
Mononuclear Tetraamineplatinum(II) Complexes: Synthesis, Anticancer Activity, DNA Binding, and Cellular Uptake
Robillard, Marc S., Jansen, Bart A. J., Lochner, Martin, Geneste, Hervé, Li, Yi, Brouwer, Jaap, Hesse, Manfred, Reedijk, Jan
Published in Helvetica chimica acta (17.10.2001)
Published in Helvetica chimica acta (17.10.2001)
Get full text
Journal Article
Identification and characterization of mGlu3 ligands using a high throughput FLIPR assay for detection of agonists, antagonists, and allosteric modulators
Pratt, Steven D, Mezler, Mario, Geneste, Hervé, Bakker, Margot H M, Hajduk, Philip J, Gopalakrishnan, Sujatha M
Published in Combinatorial chemistry & high throughput screening (01.08.2011)
Published in Combinatorial chemistry & high throughput screening (01.08.2011)
Get more information
Journal Article
Design and synthesis of 1,5- and 2,5-substituted tetrahydrobenzazepinones as novel potent and selective integrin αvβ3antagonists
KLING, Andreas, BACKFISCH, Gisela, DELZER, Jürgen, GENESTE, Herve, GRAEF, Claudia, HORNBERGER, Wilfried, LANGE, Udo E. W, LAUTERBACH, Arnulf, SEITZ, Werner, SUBKOWSKI, Thomas
Published in Bioorganic & medicinal chemistry (2003)
Published in Bioorganic & medicinal chemistry (2003)
Get full text
Journal Article
Design and synthesis of novel potent and selective integrin αvβ3 antagonists—Novel synthetic routes to isoquinolinone, benzoxazinone, and quinazolinone acetates
Seitz, Werner, Geneste, Hervé, Backfisch, Gisela, Delzer, Jürgen, Graef, Claudia, Hornberger, Wilfried, Kling, Andreas, Subkowski, Thomas, Zimmermann, Norbert
Published in Bioorganic & medicinal chemistry letters (15.01.2008)
Published in Bioorganic & medicinal chemistry letters (15.01.2008)
Get full text
Journal Article
Synthesis and SAR of highly potent and selective dopamine D 3-receptor antagonists: Quinolin(di)one and benzazepin(di)one derivatives
Geneste, Hervé, Backfisch, Gisela, Braje, Wilfried, Delzer, Jürgen, Haupt, Andreas, Hutchins, Charles W., King, Linda L., Lubisch, Wilfried, Steiner, Gerd, Teschendorf, Hans-Jürgen, Unger, Liliane, Wernet, Wolfgang
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Get full text
Journal Article
Design and synthesis of novel potent and selective integrin α v β 3 antagonists—Novel synthetic routes to isoquinolinone, benzoxazinone, and quinazolinone acetates
Seitz, Werner, Geneste, Hervé, Backfisch, Gisela, Delzer, Jürgen, Graef, Claudia, Hornberger, Wilfried, Kling, Andreas, Subkowski, Thomas, Zimmermann, Norbert
Published in Bioorganic & medicinal chemistry letters (2008)
Published in Bioorganic & medicinal chemistry letters (2008)
Get full text
Journal Article
Design and synthesis of novel potent and selective integrin ανβ3 antagonists : Novel synthetic routes to isoquinolinone, benzoxazinone, and quinazolinone acetates
SEITZ, Werner, GENESTE, Hervé, BACKFISCH, Gisela, DELZER, Jürgen, GRAEF, Claudia, HORNBERGER, Wilfried, KLING, Andreas, SUBKOWSKI, Thomas, ZIMMERMANN, Norbert
Published in Bioorganic & medicinal chemistry letters (2008)
Get full text
Published in Bioorganic & medicinal chemistry letters (2008)
Journal Article
Synthesis and SAR of N-substituted dibenzazepinone derivatives as novel potent and selective αVβ3 antagonists
KLING, Andreas, BACKFISCH, Gisela, SEITZ, Werner, SUBKOWSKI, Thomas, DELZER, Jürgen, GENESTE, Hervé, GRAEF, Claudia, HOLZENKAMP, Uta, HORNBERGER, Wilfried, LANGE, Udo E. W, LAUTERBACH, Arnulf, MACK, Helmut
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
Get full text
Journal Article
Synthesis and SAR of highly potent and selective dopamine D(3)-receptor antagonists: 1H-pyrimidin-2-one derivatives
Geneste, Hervé, Backfisch, Gisela, Braje, Wilfried, Delzer, Jürgen, Haupt, Andreas, Hutchins, Charles W, King, Linda L, Kling, Andreas, Teschendorf, Hans-Jürgen, Unger, Liliane, Wernet, Wolfgang
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Get full text
Published in Bioorganic & medicinal chemistry letters (01.02.2006)
Journal Article