Structural basis of ligand recognition in 5-HT3 receptors
Kesters, Divya, Thompson, Andrew J, Brams, Marijke, van Elk, René, Spurny, Radovan, Geitmann, Matthis, Villalgordo, Jose M, Guskov, Albert, Helena Danielson, U, Lummis, Sarah C R, Smit, August B, Ulens, Chris
Published in EMBO reports (01.01.2013)
Published in EMBO reports (01.01.2013)
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Journal Article
Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1
Yang, Jie, Talibov, Vladimir O, Peintner, Stefan, Rhee, Claire, Poongavanam, Vasanthanathan, Geitmann, Matthis, Sebastiano, Matteo Rossi, Simon, Bernd, Hennig, Janosch, Dobritzsch, Doreen, Danielson, U. Helena, Kihlberg, Jan
Published in ACS omega (03.03.2020)
Published in ACS omega (03.03.2020)
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Journal Article
A Protein Interaction Node at the Neurotransmitter Release Site: Domains of Aczonin/Piccolo, Bassoon, CAST, and Rim Converge on the N-Terminal Domain of Munc13-1
Wang, Xiaolu, Hu, Bin, Zieba, Agata, Neumann, Nicole G, Kasper-Sonnenberg, Monika, Honsbein, Annegret, Hultqvist, Greta, Conze, Tim, Witt, Wolfgang, Limbach, Christoph, Geitmann, Matthis, Danielson, Helena, Kolarow, Richard, Niemann, Gesa, Lessmann, Volkmar, Kilimann, Manfred W
Published in The Journal of neuroscience (07.10.2009)
Published in The Journal of neuroscience (07.10.2009)
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Journal Article
Identification and Characterization of an Irreversible Inhibitor of CDK2
Anscombe, Elizabeth, Meschini, Elisa, Mora-Vidal, Regina, Martin, Mathew P., Staunton, David, Geitmann, Matthis, Danielson, U. Helena, Stanley, Will A., Wang, Lan Z., Reuillon, Tristan, Golding, Bernard T., Cano, Celine, Newell, David R., Noble, Martin E.M., Wedge, Stephen R., Endicott, Jane A., Griffin, Roger J.
Published in Chemistry & biology (17.09.2015)
Published in Chemistry & biology (17.09.2015)
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Journal Article
Abstract 3843: LSD1 modulation by allosteric ligands
Emond, Wei B., Geitmann, Matthis, Jarvius, Malin, Koehler, Konrad, Källblad, Per, Niklasson, Mia, Parrow, Vendela, Sawant, Rajiv, Sjöberg, Maria, Winquist, Johan, Segerman, Anna, Bremberg, Ulf
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract LB029: Degraders of TEAD transcription factors based on interface 3 binders
Sawant, Rajiv, Geitmann, Matthis, Gossas, Thomas, Emond, Wei B., Bremberg, Ulf, Koehler, Konrad, Ceribelli, Michele, Thomas, Craig J., Brandt, Peter
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Journal Article
Deconstruction of Non-Nucleoside Reverse Transcriptase Inhibitors of Human Immunodeficiency Virus Type 1 for Exploration of the Optimization Landscape of Fragments
Brandt, Peter, Geitmann, Matthis, Danielson, U. Helena
Published in Journal of medicinal chemistry (10.02.2011)
Published in Journal of medicinal chemistry (10.02.2011)
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Journal Article
Development of 5-hydroxypyrazole derivatives as reversible inhibitors of lysine specific demethylase 1
Mould, Daniel P., Bremberg, Ulf, Jordan, Allan M., Geitmann, Matthis, Maiques-Diaz, Alba, McGonagle, Alison E., Small, Helen F., Somervaille, Tim C.P., Ogilvie, Donald
Published in Bioorganic & medicinal chemistry letters (15.07.2017)
Published in Bioorganic & medicinal chemistry letters (15.07.2017)
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Journal Article
Development and evaluation of 4-(pyrrolidin-3-yl)benzonitrile derivatives as inhibitors of lysine specific demethylase 1
Mould, Daniel P., Bremberg, Ulf, Jordan, Allan M., Geitmann, Matthis, McGonagle, Alison E., Somervaille, Tim C.P., Spencer, Gary J., Ogilvie, Donald J.
Published in Bioorganic & medicinal chemistry letters (15.10.2017)
Published in Bioorganic & medicinal chemistry letters (15.10.2017)
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Journal Article
Abstract 705: Potentiation of immunotherapy by LSD1 modulation
Emond, Wei B., Sawant, Rajiv, Geitmann, Matthis, Winquist, Johan, Brandt, Peter, Bremberg, Ulf, Källblad, Per, Parrow, Vendela, Andersson, Claes, Blom, Kristin, Najafi, Nasrin, Bergström, Tobias, Swartling, Fredrik J., Hellström, Mats, Koehler, Konrad F.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Identification of a Novel Scaffold for Allosteric Inhibition of Wild Type and Drug Resistant HIV-1 Reverse Transcriptase by Fragment Library Screening
Geitmann, Matthis, Elinder, Malin, Seeger, Christian, Brandt, Peter, de Esch, Iwan J. P, Danielson, U. Helena
Published in Journal of medicinal chemistry (10.02.2011)
Published in Journal of medicinal chemistry (10.02.2011)
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Journal Article
Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1
Mould, Daniel P, Alli, Cristina, Bremberg, Ulf, Cartic, Sharon, Jordan, Allan M, Geitmann, Matthis, Maiques-Diaz, Alba, McGonagle, Alison E, Somervaille, Tim C. P, Spencer, Gary J, Turlais, Fabrice, Ogilvie, Donald
Published in Journal of medicinal chemistry (12.10.2017)
Published in Journal of medicinal chemistry (12.10.2017)
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Journal Article
Surface Plasmon Resonance Biosensor Based Fragment Screening Using Acetylcholine Binding Protein Identifies Ligand Efficiency Hot Spots (LE Hot Spots) by Deconstruction of Nicotinic Acetylcholine Receptor alpha 7 Ligands
de Kloe, Gerdien E., Retra, Kim, Geitmann, Matthis, Kallblad, Per, Nahar, Tariq, van Elk, Rene, Smit, August B., van Muijlwijk-Koezen, Jacqueline E., Leurs, Rob, Irth, Hubertus, Danielson, U. Helena, de Esch, Iwan J. P.
Published in Journal of medicinal chemistry (14.10.2010)
Published in Journal of medicinal chemistry (14.10.2010)
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Journal Article
Surface Plasmon Resonance Biosensor Based Fragment Screening Using Acetylcholine Binding Protein Identifies Ligand Efficiency Hot Spots (LE Hot Spots) by Deconstruction of Nicotinic Acetylcholine Receptor α7 Ligands
de Kloe, Gerdien E, Retra, Kim, Geitmann, Matthis, Källblad, Per, Nahar, Tariq, van Elk, René, Smit, August B, van Muijlwijk-Koezen, Jacqueline E, Leurs, Rob, Irth, Hubertus, Danielson, U. Helena, de Esch, Iwan J. P
Published in Journal of medicinal chemistry (14.10.2010)
Published in Journal of medicinal chemistry (14.10.2010)
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Journal Article
Interaction Kinetic and Structural Dynamic Analysis of Ligand Binding to Acetylcholine-Binding Protein
Geitmann, Matthis, Retra, Kim, de Kloe, Gerdien E, Homan, Evert, Smit, August B, de Esch, Iwan J. P, Danielson, U. Helena
Published in Biochemistry (Easton) (21.09.2010)
Published in Biochemistry (Easton) (21.09.2010)
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Journal Article
Experimental validation of a fragment library for lead discovery using SPR biosensor technology
Elinder, Malin, Geitmann, Matthis, Gossas, Thomas, Källblad, Per, Winquist, Johan, Nordström, Helena, Hämäläinen, Markku, Danielson, U Helena
Published in Journal of biomolecular screening (01.01.2011)
Published in Journal of biomolecular screening (01.01.2011)
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