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Aryl bis-sulfonamides bind to the active site of a homotrimeric isoprenoid biosynthesis enzyme IspF and extract the essential divalent metal cation cofactorElectronic supplementary information (ESI) available: Experimental procedures for the protein expression and purification, protein denaturation, buffer exchange and data analysis (PDF). See DOI: 10.1039/c8sc00814k
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Aryl bis-sulfonamides bind to the active site of a homotrimeric isoprenoid biosynthesis enzyme IspF and extract the essential divalent metal cation cofactor† †Electronic supplementary information (ESI) available: Experimental procedures for the protein expression and purification, protein denaturation, buffer exchange and data analysis (PDF). See DOI: 10.1039/c8sc00814k
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