Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure
Follmann, Markus, Ackerstaff, Jens, Redlich, Gorden, Wunder, Frank, Lang, Dieter, Kern, Armin, Fey, Peter, Griebenow, Nils, Kroh, Walter, Becker-Pelster, Eva-Maria, Kretschmer, Axel, Geiss, Volker, Li, Volkhart, Straub, Alexander, Mittendorf, Joachim, Jautelat, Rolf, Schirok, Hartmut, Schlemmer, Karl-Heinz, Lustig, Klemens, Gerisch, Michael, Knorr, Andreas, Tinel, Hanna, Mondritzki, Thomas, Trübel, Hubert, Sandner, Peter, Stasch, Johannes-Peter
Published in Journal of medicinal chemistry (22.06.2017)
Published in Journal of medicinal chemistry (22.06.2017)
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The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats
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Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
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Design and Synthesis of Potent and Selective Azaindole-Based Rho Kinase (ROCK) Inhibitors
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Published in ChemMedChem (15.12.2008)
Published in ChemMedChem (15.12.2008)
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Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042)
Hahn, Michael G, Lampe, Thomas, El Sheikh, Sherif, Griebenow, Nils, Woltering, Elisabeth, Schlemmer, Karl-Heinz, Dietz, Lisa, Gerisch, Michael, Wunder, Frank, Becker-Pelster, Eva-Maria, Mondritzki, Thomas, Tinel, Hanna, Knorr, Andreas, Kern, Armin, Lang, Dieter, Hueser, Joerg, Schomber, Tibor, Benardeau, Agnes, Eitner, Frank, Truebel, Hubert, Mittendorf, Joachim, Kumar, Vijay, van den Akker, Focco, Schaefer, Martina, Geiss, Volker, Sandner, Peter, Stasch, Johannes-Peter
Published in Journal of medicinal chemistry (13.05.2021)
Published in Journal of medicinal chemistry (13.05.2021)
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Runcaciguat, a Novel Soluble Guanylate Cyclase (sGC) Activator, Shows Kidney Protection in Models of CKD: SA-PO247
Kraehling, Jan R., Schomber, Tibor, Benardeau, Agnes M., Kahnert, Antje, Popp, Laura, Vienenkoetter, Julia, Ellinger-Ziegelbauer, Heidrun C., Pavkovic, Mira, Kretschmer, Axel, Lawrenz, Bettina, Hartmann, Elke, Siudak, Krystyna, Freyberger, Alexius, Hagelschuer, Ina, Mathar, Ilka, Hüser, Jörg, Hahn, Michael G., Stasch, Johannes-Peter, Geiss, Volker, Eitner, Frank, Sandner, Peter
Published in Journal of the American Society of Nephrology (01.11.2022)
Published in Journal of the American Society of Nephrology (01.11.2022)
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New Generation of sGC Stimulators: Discovery of Imidazo[1,2‑a]pyridine Carboxamide BAY 1165747 (BAY-747), a Long-Acting Soluble Guanylate Cyclase Stimulator for the Treatment of Resistant Hypertension
Vakalopoulos, Alexandros, Wunder, Frank, Hartung, Ingo V., Redlich, Gorden, Jautelat, Rolf, Buchgraber, Philipp, Hassfeld, Jorma, Gromov, Alexey V., Lindner, Niels, Bierer, Donald, Gries, Jörg, Kroh, Walter, Paulsen, Holger, Mittendorf, Joachim, Lang, Dieter, Becker-Pelster, Eva, Brockschnieder, Damian, Geiss, Volker, Li, Volkhart, Straub, Alexander, Knorr, Andreas, Mondritzki, Thomas, Trübel, Hubert, Raschke, Marian, Schaefer, Martina, Thomas, Dirk, Sandner, Peter, Stasch, Johannes-Peter, Follmann, Markus
Published in Journal of medicinal chemistry (08.06.2023)
Published in Journal of medicinal chemistry (08.06.2023)
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SUBSTITUTED PIPERIDINYL-TETRAHYDROQUINOLINES AND THEIR USE AS ALPHA-2C ADRENORECEPTOR ANTAGONISTS
KAST RAIMUND, GOELLER ANDREAS, KNORR ANDREAS, LANG DIETER, BUCHGRABER PHILIPP, BECKER PELSTER EVA MARIA, ENGEL KAREN, HIMMEL HERBERT, WUNDER FRANK, REDLICH GORDEN, TINEL HANNA, BUCHMUELLER ANJA, SCHMECK CARSTEN, GEISS VOLKER
Year of Publication 18.08.2016
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Year of Publication 18.08.2016
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SUBSTITUTED PIPERIDINYL-TETRAHYDROQUINOLINES
KAST RAIMUND, GOELLER ANDREAS, KNORR ANDREAS, LANG DIETER, BUCHGRABER PHILIPP, BECKER PELSTER EVA MARIA, ENGEL KAREN, HIMMEL HERBERT, WUNDER FRANK, REDLICH GORDEN, TINEL HANNA, BUCHMUELLER ANJA, SCHMECK CARSTEN, GEISS VOLKER
Year of Publication 18.08.2016
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Year of Publication 18.08.2016
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TRIAZOLE DERIVATIVES AS VASOPRESSIN-RECEPTOR INHIBITORS FOR TREATING CARDIAC INSUFFICIENCY
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Year of Publication 15.12.2011
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Year of Publication 15.12.2011
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SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF
TRUEBEL HUBERT, DELBECK MARTINA, KRETSCHMER AXEL, BRUEGGEMEIER ULF, KERN ARMIN, POOK ELISABETH, FUERSTNER CHANTAL, KELDENICH JOERG, SCHMECK CARSTEN, KOLKHOF PETER, GEISS VOLKER
Year of Publication 28.11.2011
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Year of Publication 28.11.2011
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Cover Picture: Design and Synthesis of Potent and Selective Azaindole-Based Rho Kinase (ROCK) Inhibitors (ChemMedChem 12/2008)
Schirok, Hartmut, Kast, Raimund, Figueroa-Pérez, Santiago, Bennabi, Samir, Gnoth, Mark J., Feurer, Achim, Heckroth, Heike, Thutewohl, Michael, Paulsen, Holger, Knorr, Andreas, Hütter, Joachim, Lobell, Mario, Münter, Klaus, Geiß, Volker, Ehmke, Heimo, Lang, Dieter, Radtke, Martin, Mittendorf, Joachim, Stasch, Johannes-Peter
Published in ChemMedChem (15.12.2008)
Published in ChemMedChem (15.12.2008)
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SUBSTITUTED PIPERIDINYL-TETRAHYDROQUINOLINES AND THEIR USE AS ALPHA-2C ADRENORECEPTOR ANTAGONISTS
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Year of Publication 29.11.2022
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Year of Publication 29.11.2022
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THE USE OF SGC STIMULATORS AND SGC ACTIVATORS ALONE OR IN COMBINATION WITH PDE5 INHIBITORS FOR THE TREATMENT OF BONE DISORDERS INCLUDING OSTEOGENESIS IMPERFECTA (OI)
FOLLMANN, Markus, SANDNER, Peter, GEIß, Volker, FREY, Reiner, STASCH, Johannes-Peter
Year of Publication 19.06.2019
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Year of Publication 19.06.2019
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Year of Publication 26.11.2021
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Year of Publication 26.11.2021
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Substituted piperidinyl-tetrahydroquinolines and their use as alpha-2c adrenoreceptor antagonists
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Year of Publication 30.07.2021
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Year of Publication 30.07.2021
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Year of Publication 30.03.2021
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Year of Publication 30.03.2021
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Substituted piperidinyl-tetrahydroquinolines and their use as alpha-2c adrenoreceptor antagonists
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Year of Publication 22.10.2020
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Year of Publication 22.10.2020
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SUBSTITUTED PIPERIDINYL-TETRAHYDROQUINOLINES AND THEIR USE AS ALPHA-2C ADRENORECEPTOR ANTAGONISTS
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Year of Publication 14.09.2020
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Year of Publication 14.09.2020
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Substituted piperidinyl tetrahydroquinolines
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Year of Publication 18.06.2019
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Year of Publication 18.06.2019
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Substituted piperidinyl-tetrahydroquinolines and their use as alpha-2c adrenoreceptor antagonists
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Year of Publication 16.05.2019
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Year of Publication 16.05.2019
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