A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner
Stemmer, Willem P C, Schellenberger, Volker, Wang, Chia-wei, Geething, Nathan C, Spink, Benjamin J, Campbell, Andrew, To, Wayne, Scholle, Michael D, Yin, Yong, Yao, Yi, Bogin, Oren, Cleland, Jeffrey L, Silverman, Joshua
Published in Nature biotechnology (01.12.2009)
Published in Nature biotechnology (01.12.2009)
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Journal Article
Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose
Geething, Nathan C, To, Wayne, Spink, Benjamin J, Scholle, Michael D, Wang, Chia-wei, Yin, Yong, Yao, Yi, Schellenberger, Volker, Cleland, Jeffrey L, Stemmer, Willem P C, Silverman, Joshua
Published in PloS one (14.04.2010)
Published in PloS one (14.04.2010)
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Journal Article
A Novel Long-Acting Human Growth Hormone Fusion Protein (VRS-317): Enhanced In Vivo Potency and Half-Life
Cleland, Jeffrey L., Geething, Nathan C., Moore, Jerome A., Rogers, Brian C., Spink, Benjamin J., Wang, Chai-Wei, Alters, Susan E., Stemmer, Willem P.C., Schellenberger, Volker
Published in Journal of pharmaceutical sciences (01.08.2012)
Published in Journal of pharmaceutical sciences (01.08.2012)
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Journal Article
Drs2p-Dependent Formation of Exocytic Clathrin-Coated Vesicles In Vivo
Gall, Walter E, Geething, Nathan C, Hua, Zhaolin, Ingram, Michael F, Liu, Ke, Chen, Sophie I, Graham, Todd R
Published in Current biology (17.09.2002)
Published in Current biology (17.09.2002)
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Journal Article
GLUCAGON-LIKE PEPTIDE-2 COMPOSITIONS AND METHODS OF MAKING AND USING SAME
GEETHING NATHAN, WANG CHIA WEI, STEMMER WILLEM P, SILVERMAN JOSHUA, SCHELLENBERGER VOLKER, SPINK BENJAMIN
Year of Publication 09.06.2014
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Year of Publication 09.06.2014
Patent
GROWTH HORMONE POLYPEPTIDES AND METHODS OF MAKING AND USING SAME
GEETHING NATHAN, CLELAND JEFFREY L, WANG CHIA WEI, STEMMER WILLEM P, SILVERMAN JOSHUA, SCHELLENBERGER VOLKER
Year of Publication 18.04.2012
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Year of Publication 18.04.2012
Patent
FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
CHANG PEI YUN, JIANG HAIYAN, DING SHENG, VARFAJ FATBARDHA, PETERS ROBERT, SPINK BENJAMIN, LIU TONGYAO, GEETHING NATHAN, MEI BAISONG, KULMAN JOHN, WANG CHIA WEI, WANG DEPING, STEMMER WILLEM P, SILVERMAN JOSHUA, SCHELLENBERGER VOLKER, TOBY GARABET G
Year of Publication 21.11.2014
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Year of Publication 21.11.2014
Patent
COMPOSITIONS AND METHODS FOR MODIFYING PROPERTIES OF BIOLOGICALLY ACTIVE POLYPEPTIDES
YIN YONG, WANG CHIA WEI, STEMMER WILLEM P, BOGIN OREN, GEETHING NATHAN C, SCHELLENBERGER VOLKER
Year of Publication 03.06.2010
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Year of Publication 03.06.2010
Patent
GLUCAGON-LIKE PEPTIDE-2 COMPOSITIONS AND METHODS OF MAKING AND USING SAME
STEMMER, Willem P, GEETHING, Nathan, SCHELLENBERGER, Volker, WANG, Chia-wei, SILVERMAN, Joshua, SPINK, Benjamin
Year of Publication 29.02.2024
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Year of Publication 29.02.2024
Patent
EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME
GEETHING NATHAN, TO WAYNE, CLELAND JEFFREY L, WANG CHIA WEI, STEMMER WILLEM P, SILVERMAN JOSHUA, SCHELLENBERGER VOLKER, SPINK BENJAMIN
Year of Publication 25.11.2011
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Year of Publication 25.11.2011
Patent
Extended recombinant polypeptides and compositions comprising same
Stemmer, Willem P, To, Wayne, Geething, Nathan, Silverman, Joshua, Wang, Chia-wei, Schellenberger, Volker, Cleland, Jeffrey L, Spink, Benjamin
Year of Publication 27.08.2024
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Year of Publication 27.08.2024
Patent
GLUCAGON-LIKE PEPTIDE-2 COMPOSITIONS AND METHODS OF MAKING AND USING SAME
SPINK, BENJAMIN, SCHELLENBERGER, VOLKER, SILVERMAN, JOSHUA, WANG, CHIA-WEI, STEMMER, WILLEM P, GEETHING, NATHAN
Year of Publication 04.04.2023
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Year of Publication 04.04.2023
Patent
GLUCOSE-REGULATING POLYPEPTIDES AND METHODS OF MAKING AND USING SAME
STEMMER, Willem, P, GEETHING, Nathan, SCHELLENBERGER, Volker, WANG, Chia-wei, SILVERMAN, Joshua, CLELAND, Jeffrey. L, SPINK, Benjamin
Year of Publication 22.02.2023
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Year of Publication 22.02.2023
Patent
FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
Ding, Sheng, Wang, Deping, Geething, Nathan, Wang, Chia-wei, Schellenberger, Volker, Toby, Garabet G, Liu, Tongyao, Peters, Robert, Jiang, Haiyan, Mei, Baisong, Chang, Pei-Yun, Stemmer, Willem P, Kulman, John, Silverman, Joshua, Spink, Benjamin, Varfaj, Fatbardha
Year of Publication 12.10.2023
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Year of Publication 12.10.2023
Patent
GLUCAGON-LIKE PEPTIDE-2 COMPOSITIONS AND METHODS OF MAKING AND USING SAME
Stemmer, Willem P, Geething, Nathan, Silverman, Joshua, Wang, Chia-wei, Schellenberger, Volker, Spink, Benjamin
Year of Publication 17.12.2020
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Year of Publication 17.12.2020
Patent
EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME
Stemmer, Willem P, To, Wayne, Geething, Nathan, Cleland, Jerrfey L, Silverman, Joshua, Wang, Chia-wei, Schellenberger, Volker, Spink, Benjamin
Year of Publication 09.09.2021
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Year of Publication 09.09.2021
Patent
COAGULATION FACTOR IX COMPOSITIONS AND METHODS OF MAKING AND USING SAME
STEMMER, Willem P, SCHELLENBERGER, Volker, WANG, Chia-wei, TO, Wayne, SILVERMAN, Joshua, GEETHING, Nathan C, SPINK, Benjamin
Year of Publication 09.09.2021
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Year of Publication 09.09.2021
Patent