α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
Gitler, Aaron D, Cooper, Antony A, Rochet, Jean-Christophe, Strathearn, Katherine E, Hill, Kathryn J, Chesi, Alessandra, Geddie, Melissa L, Caldwell, Kim A, Lindquist, Susan, Hamamichi, Shusei, Caldwell, Guy A
Published in Nature genetics (01.03.2009)
Published in Nature genetics (01.03.2009)
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Journal Article
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity
Karger, David R, Fraenkel, Ernest, Su, Linhui Julie, Geddie, Melissa L, King, Oliver D, Riva, Laura, Yeger-Lotem, Esti, Cashikar, Anil G, Lindquist, Susan, Auluck, Pavan K, Gitler, Aaron D, Valastyan, Julie S
Published in Nature genetics (01.03.2009)
Published in Nature genetics (01.03.2009)
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Journal Article
A novel screening method to assess developability of antibody-like molecules
Kohli, Neeraj, Jain, Nidhi, Geddie, Melissa L, Razlog, Maja, Xu, Lihui, Lugovskoy, Alexey A
Published in mAbs (04.07.2015)
Published in mAbs (04.07.2015)
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Journal Article
MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM
Casaletto, Jessica B., Geddie, Melissa L., Abu-Yousif, Adnan O., Masson, Kristina, Fulgham, Aaron, Boudot, Antoine, Maiwald, Tim, Kearns, Jeffrey D., Kohli, Neeraj, Su, Stephen, Razlog, Maja, Raue, Andreas, Kalra, Ashish, Håkansson, Maria, Logan, Derek T., Welin, Martin, Chattopadhyay, Shrikanta, Harms, Brian D., Nielsen, Ulrik B., Schoeberl, Birgit, Lugovskoy, Alexey A., MacBeath, Gavin
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (09.04.2019)
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Journal Article
Polyamine pathway contributes to the pathogenesis of Parkinson disease
Lewandowski, Nicole M., Ju, Shulin, Verbitsky, Miguel, Ross, Barbara, Geddie, Melissa L., Rockenstein, Edward, Adame, Anthony, Muhammad, Alim, Vonsattel, Jean Paul, Ringe, Dagmar, Cote, Lucien, Lindquist, Susan, Masliah, Eliezer, Petsko, Gregory A., Marder, Karen, Clark, Lorraine N., Small, Scott A.
Published in Proceedings of the National Academy of Sciences - PNAS (28.09.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (28.09.2010)
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Journal Article
Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse models
Kamoun, Walid S., Kirpotin, Dmitri B., Huang, Zhaohua Richard, Tipparaju, Suresh K., Noble, Charles O., Hayes, Mark E., Luus, Lia, Koshkaryev, Alexander, Kim, Jaeyeon, Olivier, Ken, Kornaga, Tad, Oyama, Shinji, Askoxylakis, Vasileios, Pien, Christine, Kuesters, Geoffrey, Dumont, Nancy, Lugovskoy, Alexey A., Schihl, Sarah A., Wilton, John H., Geddie, Melissa L., Suchy, James, Grabow, Stephanie, Kohli, Neeraj, Reynolds, C. Patrick, Blaydes, Rachel, Zhou, Yu, Sawyer, Andrew J., Marks, James D., Drummond, Daryl C.
Published in Nature biomedical engineering (01.04.2019)
Published in Nature biomedical engineering (01.04.2019)
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Improving the developability of an anti-EphA2 single-chain variable fragment for nanoparticle targeting
Geddie, Melissa L, Kohli, Neeraj, Kirpotin, Dmitri B, Razlog, Maja, Jiao, Yang, Kornaga, Tad, Rennard, Rachel, Xu, Lihui, Schoerberl, Birgit, Marks, James D, Drummond, Daryl C, Lugovskoy, Alexey A
Published in mAbs (01.01.2017)
Published in mAbs (01.01.2017)
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Journal Article
Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle
Zhang, Kathy, Geddie, Melissa L, Kohli, Neeraj, Kornaga, Tad, Kirpotin, Dmitri B, Jiao, Yang, Rennard, Rachel, Drummond, Daryl C, Nielsen, Ulrik B, Xu, Lihui, Lugovskoy, Alexey A
Published in mAbs (01.01.2015)
Published in mAbs (01.01.2015)
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Journal Article
A Comparison of Directed Evolution Approaches Using the β-Glucuronidase Model System
Rowe, Lori A., Geddie, Melissa L., Alexander, Omar B., Matsumura, Ichiro
Published in Journal of molecular biology (26.09.2003)
Published in Journal of molecular biology (26.09.2003)
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Journal Article
High throughput microplate screens for directed protein evolution
Geddie, Melissa L, Rowe, Lori A, Alexander, Omar B, Matsumura, Ichiro
Published in Methods in enzymology (2004)
Published in Methods in enzymology (2004)
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Abstract 22: MM-161, a first-in-class pan-FGFR antibody
Dake, Tamara, Finn, Greg, Geddie, Melissa, Kohli, Neeraj, Razlog, Maja, Xu, Lihui, Paragas, Violette, Yuzugullu, Haluk, Ghassemifar, Sara, Hashambhoy-Ramsay, Yasmin, McDonagh, Charlotte, Muda, Marco, Schoeberl, Birgit
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 1690: Mechanistic characterization of MM-131, a bispecific antibody that blocks c-Met signaling through concurrent targeting of EpCAM
Abu-Yousif, Adnan O., Casaletto, Jessica B., Masson, Kristina, Fulgham, Aaron, Geddie, Melissa, Schoeberl, Birgit, Nielsen, Ulrik, MacBeath, Gavin
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 750: Nanoliposomal targeting of Ephrin receptor A2 (EphA2): Clinical translation
Kamoun, Walid S., Oyama, Shinji, Kornaga, Tad, Feng, Theresa, Luus, Lia, Pham, Minh T., Kirpotin, Dmitri B., Marks, James D., Geddie, Melissa, Xu, Lihui, Lugovskoy, Alexey A., Murphy, Monica, Morrisson, Carl, Drummond, Daryl C.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 871: Nanoliposomal targeting of ephrin receptor A2 (EphA2): Preclinical in vitro and in vivo rationale
Kamoun, Walid S., Luus, Lia, Pien, Christine, Kornaga, Tad, Oyama, Shinji, Huang, Zhaohua Richard, Tipparaju, Suresh, Kirpotin, Dmitri B., Marks, James D., Koshkaryev, Alexander, Geddie, Melissa, Xu, Lihui, Lugovosky, Alexey, Drummond, Daryl C.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
단백질 A 결합 펩타이드, 항-EphA2 항체 및 이의 사용 방법
DRUMMOND DARYL, KIRPOTIN DMITRI, MARKS JAMES D, GEDDIE MELISSA, KOHLI NEERAJ, LUGOVSKY ALEXEY
Year of Publication 28.11.2018
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Year of Publication 28.11.2018
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