Non‐internalizing antibody–drug conjugates display potent anti‐cancer activity upon proteolytic release of monomethyl auristatin E in the subendothelial extracellular matrix
Gébleux, Rémy, Stringhini, Marco, Casanova, Ruben, Soltermann, Alex, Neri, Dario
Published in International journal of cancer (01.04.2017)
Published in International journal of cancer (01.04.2017)
Get full text
Journal Article
Partially shielded enzymes capable of processing large protein substrates
Briand, Manon L, Gebleux, Remy, Richina, Federica, Correro, M. Rita, Grether, Yasmin, Dudal, Yves, Braga-Lagache, Sophie, Heller, Manfred, Beerli, Roger R, Grawunder, Ulf, Corvini, Philippe F.-X, Shahgaldian, Patrick
Published in Chemical communications (Cambridge, England) (11.05.2020)
Published in Chemical communications (Cambridge, England) (11.05.2020)
Get full text
Journal Article
면역리간드-페이로드 접합체의 생성을 위한 생체촉매 조성물 및 용도
GRAWUNDER ULF, BEERLI ROGER R, CORVINI PHILIPPE F. X, GEBLEUX REMY, DUDAL YVES, CORRERO MARIA RITA, SHAHGALDIAN PATRICK, BRIAND MANON
Year of Publication 11.01.2024
Get full text
Year of Publication 11.01.2024
Patent
Highly Potent, Anthracycline-based Antibody-Drug Conjugates Generated by Enzymatic, Site-specific Conjugation
Stefan, Nikolas, Gébleux, Rémy, Waldmeier, Lorenz, Hell, Tamara, Escher, Marie, Wolter, Fabian I, Grawunder, Ulf, Beerli, Roger R
Published in Molecular cancer therapeutics (01.05.2017)
Published in Molecular cancer therapeutics (01.05.2017)
Get full text
Journal Article
A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer
D'Amico, Lucia, Menzel, Ulrike, Prummer, Michael, Müller, Philipp, Buchi, Mélanie, Kashyap, Abhishek, Haessler, Ulrike, Yermanos, Alexander, Gébleux, Rémy, Briendl, Manfred, Hell, Tamara, Wolter, Fabian I, Beerli, Roger R, Truxova, Iva, Radek, Špíšek, Vlajnic, Tatjana, Grawunder, Ulf, Reddy, Sai, Zippelius, Alfred
Published in Journal for immunotherapy of cancer (21.01.2019)
Published in Journal for immunotherapy of cancer (21.01.2019)
Get full text
Journal Article
Characterization of the housekeeping sortase from the human pathogen Propionibacterium acnes : first investigation of a class F sortase
Di Girolamo, Salvatore, Puorger, Chasper, Castiglione, Mara, Vogel, Maren, Gébleux, Rémy, Briendl, Manfred, Hell, Tamara, Beerli, Roger R, Grawunder, Ulf, Lipps, Georg
Published in Biochemical journal (28.02.2019)
Published in Biochemical journal (28.02.2019)
Get more information
Journal Article
Cost-effective large-scale expression of proteins for NMR studies
Klopp, Julia, Winterhalter, Aurélie, Gébleux, Rémy, Scherer-Becker, Daniela, Ostermeier, Christian, Gossert, Alvar D.
Published in Journal of biomolecular NMR (01.08.2018)
Published in Journal of biomolecular NMR (01.08.2018)
Get full text
Journal Article
NBE-002: A novel anthracycline-based antibody-drug conjugate (ADC) targeting ROR1 for the treatment of advanced solid tumors—A phase 1/2 clinical trial
Tolcher, Anthony W., Meric-Bernstam, Funda, McKean, Meredith, Beerli, Roger R, Waldmeier, Lorenz, Gebleux, Rémy, Hellmann, Ina, Chrom, Pawel, Grawunder, Ulf
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
Get full text
Journal Article