Efficient base editing for multiple genes and loci in pigs using base editors
Xie, Jingke, Ge, Weikai, Li, Nan, Liu, Qishuai, Chen, Fangbing, Yang, Xiaoyu, Huang, Xingyun, Ouyang, Zhen, Zhang, Quanjun, Zhao, Yu, Liu, Zhaoming, Gou, Shixue, Wu, Han, Lai, Chengdan, Fan, Nana, Jin, Qin, Shi, Hui, Liang, Yanhui, Lan, Ting, Quan, Longquan, Li, Xiaoping, Wang, Kepin, Lai, Liangxue
Published in Nature communications (28.06.2019)
Published in Nature communications (28.06.2019)
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ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems
Xie, Jingke, Huang, Xingyun, Wang, Xia, Gou, Shixue, Liang, Yanhui, Chen, Fangbing, Li, Nan, Ouyang, Zhen, Zhang, Quanjun, Ge, Weikai, Jin, Qin, Shi, Hui, Zhuang, Zhenpeng, Zhao, Xiaozhu, Lian, Meng, Wang, Jiaowei, Ye, Yinghua, Quan, Longquan, Wu, Han, Wang, Kepin, Lai, Liangxue
Published in BMC biology (23.09.2020)
Published in BMC biology (23.09.2020)
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Doxycycline-dependent Cas9-expressing pig resources for conditional in vivo gene nullification and activation
Jin, Qin, Liu, Xiaoyi, Zhuang, Zhenpeng, Huang, Jiayuan, Gou, Shixue, Shi, Hui, Zhao, Yu, Ouyang, Zhen, Liu, Zhaoming, Li, Lei, Mao, Junjie, Ge, Weikai, Chen, Fangbing, Yu, Manya, Guan, Yezhi, Ye, Yinghua, Tang, Chengcheng, Huang, Ren, Wang, Kepin, Lai, Liangxue
Published in Genome Biology (17.01.2023)
Published in Genome Biology (17.01.2023)
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Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses
Li, Wenjing, Shi, Lei, Zhuang, Zhenpeng, Wu, Han, Lian, Meng, Chen, Yihui, Li, Lei, Ge, Weikai, Jin, Qin, Zhang, Quanjun, Zhao, Yu, Liu, Zhaoming, Ouyang, Zhen, Ye, Yinghua, Li, Yingying, Wang, Hai, Liao, Yuan, Quan, Longquan, Xiao, Lei, Lai, Liangxue, Meng, Guangxun, Wang, Kepin
Published in The Journal of immunology (1950) (01.11.2020)
Published in The Journal of immunology (1950) (01.11.2020)
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XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer
Ruan, Degong, Peng, Jiangyun, Wang, Xiaoshan, Ouyang, Zhen, Zou, Qingjian, Yang, Yi, Chen, Fangbing, Ge, Weikai, Wu, Han, Liu, Zhaoming, Zhao, Yu, Zhao, Bentian, Zhang, Quanjun, Lai, Chengdan, Fan, Nana, Zhou, Zhiwei, Liu, Qishuai, Li, Nan, Jin, Qin, Shi, Hui, Xie, Jingke, Song, Hong, Yang, Xiaoyu, Chen, Jiekai, Wang, Kepin, Li, Xiaoping, Lai, Liangxue
Published in Stem cell reports (13.02.2018)
Published in Stem cell reports (13.02.2018)
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Evaluation of guide-free Cas9-induced genomic damage and transcriptome changes in pig embryos
Ge, Weikai, Zhao, Xiaozhu, Gou, Shixue, Jin, Qin, Chen, Fangbing, Ouyang, Zhen, Lai, Chengdan, Cui, Tao, Mai, Baoyi, Lu, Sijia, Zhong, Kexin, Liang, Yanhui, Chen, Tao, Wu, Han, Li, Nan, Ye, Yinghua, Lai, Liangxue, Wang, Kepin
Published in Molecular therapy. Nucleic acids (12.12.2023)
Published in Molecular therapy. Nucleic acids (12.12.2023)
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Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression
Jin, Qin, Yang, Xiaoyu, Gou, Shixue, Liu, Xiaoyi, Zhuang, Zhenpeng, Liang, Yanhui, Shi, Hui, Huang, Jiayuan, Wu, Han, Zhao, Yu, Ouyang, Zhen, Zhang, Quanjun, Liu, Zhaoming, Chen, Fangbing, Ge, Weikai, Xie, Jingke, Li, Nan, Lai, Chengdan, Zhao, Xiaozhu, Wang, Jiaowei, Lian, Meng, Li, Lei, Quan, Longquan, Ye, Yinghua, Lai, Liangxue, Wang, Kepin
Published in Science China. Life sciences (01.11.2022)
Published in Science China. Life sciences (01.11.2022)
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In vivo evaluation of guide-free Cas9-induced safety risks in a pig model
Ge, Weikai, Gou, Shixue, Zhao, Xiaozhu, Jin, Qin, Zhuang, Zhenpeng, Zhao, Yu, Liang, Yanhui, Ouyang, Zhen, Liu, Xiaoyi, Chen, Fangbing, Shi, Hui, Yan, Haizhao, Wu, Han, Lai, Liangxue, Wang, Kepin
Published in Signal transduction and targeted therapy (19.07.2024)
Published in Signal transduction and targeted therapy (19.07.2024)
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AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns
Liang, Yanhui, Xie, Jingke, Zhang, Quanjun, Wang, Xiaomin, Gou, Shixue, Lin, Lihui, Chen, Tao, Ge, Weikai, Zhuang, Zhenpeng, Lian, Meng, Chen, Fangbing, Li, Nan, Ouyang, Zhen, Lai, Chengdan, Liu, Xiaoyi, Li, Lei, Ye, Yinghua, Wu, Han, Wang, Kepin, Lai, Liangxue
Published in Nucleic acids research (20.05.2022)
Published in Nucleic acids research (20.05.2022)
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CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I
Li, Nan, Gou, Shixue, Wang, Jiaowei, Zhang, Quanjun, Huang, Xingyun, Xie, Jingke, Li, Li, Jin, Qin, Ouyang, Zhen, Chen, Fangbing, Ge, Weikai, Shi, Hui, Liang, Yanhui, Zhuang, Zhenpeng, Zhao, Xiaozhu, Lian, Meng, Ye, Yinghua, Quan, Longquan, Wu, Han, Lai, Liangxue, Wang, Kepin
Published in Molecular therapy (03.03.2021)
Published in Molecular therapy (03.03.2021)
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Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems
Wu, Han, Liu, Qishuai, Shi, Hui, Xie, Jingke, Zhang, Quanjun, Ouyang, Zhen, Li, Nan, Yang, Yi, Liu, Zhaoming, Zhao, Yu, Lai, Chengdan, Ruan, Degong, Peng, Jiangyun, Ge, Weikai, Chen, Fangbing, Fan, Nana, Jin, Qin, Liang, Yanhui, Lan, Ting, Yang, Xiaoyu, Wang, Xiaoshan, Lei, Zhiyong, Doevendans, Pieter A., Sluijter, Joost P. G., Wang, Kepin, Li, Xiaoping, Lai, Liangxue
Published in Cellular and molecular life sciences : CMLS (01.10.2018)
Published in Cellular and molecular life sciences : CMLS (01.10.2018)
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Correction: Engineered Pigs Carrying a Gain-of-Function NLRP3 Homozygous Mutation Can Survive to Adulthood and Accurately Recapitulate Human Systemic Spontaneous Inflammatory Responses
Li, Wenjing, Shi, Lei, Zhuang, Zhenpeng, Wu, Han, Lian, Meng, Chen, Yihui, Li, Lei, Ge, Weikai, Jin, Qin, Zhang, Quanjun, Zhao, Yu, Liu, Zhaoming, Ouyang, Zhen, Ye, Yinghua, Li, Yingying, Wang, Hai, Liao, Yuan, Quan, Longquan, Xiao, Lei, Lai, Liangxue, Meng, Guangxun, Wang, Kepin
Published in The Journal of immunology (1950) (01.11.2021)
Published in The Journal of immunology (1950) (01.11.2021)
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Improving the Cpf1-mediated base editing system by combining dCas9/dead sgRNA with human APOBEC3A variants
Lian, Meng, Chen, Fangbing, Huang, Xingyun, Zhao, Xiaozhu, Gou, Shixue, Li, Nan, Jin, Qin, Shi, Hui, Liang, Yanhui, Xie, Jingke, Ge, Weikai, Zhuang, Zhenpeng, Wang, Jiaowei, Ye, Yinghua, Yang, Yi, Wang, Kepin, Lai, Liangxue, Wu, Han
Published in Journal of genetics and genomics (20.01.2021)
Published in Journal of genetics and genomics (20.01.2021)
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