role of parasite persistence in pathogenesis of Chagas heart disease
GUTIERREZ, F.R.S, GUEDES, P.M.M, GAZZINELLI, R.T, SILVA, J.S
Published in Parasite immunology (01.11.2009)
Published in Parasite immunology (01.11.2009)
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Interleukin 12 is Required for the T-Lymphocyte-Independent Induction of Interferon γ by an Intracellular Parasite and Induces Resistance in T-Cell-Deficient Hosts
Gazzinelli, Ricardo T., Hieny, Sara, Wynn, Thomas A., Wolf, Stanley, Sher, Alan
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.1993)
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Activation of Toll-Like Receptor-2 by Glycosylphosphatidylinositol Anchors from a Protozoan Parasite
Campos, Marco A. S, Almeida, Igor C, Takeuchi, Osamu, Akira, Shizuo, Valente, Eneida P, Procopio, Daniela O, Travassos, Luiz R, Smith, Jason A, Golenbock, Douglas T, Gazzinelli, Ricardo T
Published in The Journal of immunology (1950) (01.07.2001)
Published in The Journal of immunology (1950) (01.07.2001)
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Immunological control of Trypanosoma cruzi infection and pathogenesis of Chagas' disease
Brener, Z, Gazzinelli, R T
Published in International archives of allergy and immunology (01.10.1997)
Published in International archives of allergy and immunology (01.10.1997)
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IL-10 inhibits parasite killing and nitrogen oxide production by IFN- gamma-activated macrophages
Gazzinelli, RT, Oswald, IP, James, SL, Sher, A
Published in The Journal of immunology (1950) (15.03.1992)
Published in The Journal of immunology (1950) (15.03.1992)
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Journal Article
Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes
ALIBERTI, J. C. S, CARDOSO, M. A. G, MARTINS, G. A, GAZZINELLI, R. T, VIEIRA, L. Q, SILVA, J. S, MANSFIELD, J. M
Published in Infection and Immunity (01.06.1996)
Published in Infection and Immunity (01.06.1996)
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In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF- alpha
Gazzinelli, RT, Wysocka, M, Hieny, S, Scharton-Kersten, T, Cheever, A, Kuhn, R, Muller, W, Trinchieri, G, Sher, A
Published in The Journal of immunology (1950) (15.07.1996)
Published in The Journal of immunology (1950) (15.07.1996)
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Journal Article
Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice
Carrera, L, Gazzinelli, R T, Badolato, R, Hieny, S, Muller, W, Kuhn, R, Sacks, D L
Published in The Journal of experimental medicine (01.02.1996)
Published in The Journal of experimental medicine (01.02.1996)
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In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection
Scharton-Kersten, TM, Wynn, TA, Denkers, EY, Bala, S, Grunvald, E, Hieny, S, Gazzinelli, RT, Sher, A
Published in The Journal of immunology (1950) (01.11.1996)
Published in The Journal of immunology (1950) (01.11.1996)
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Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-alpha and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation
Gazzinelli, RT, Eltoum, I, Wynn, TA, Sher, A
Published in The Journal of immunology (1950) (01.10.1993)
Published in The Journal of immunology (1950) (01.10.1993)
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Requirement of mitogen-activated protein kinases and I kappa B phosphorylation for induction of proinflammatory cytokines synthesis by macrophages indicates functional similarity of receptors triggered by glycosylphosphatidylinositol anchors from parasitic protozoa and bacterial lipopolysaccharide
Ropert, C, Almeida, I C, Closel, M, Travassos, L R, Ferguson, M A, Cohen, P, Gazzinelli, R T
Published in The Journal of immunology (1950) (01.03.2001)
Published in The Journal of immunology (1950) (01.03.2001)
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Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: tissue parasitism and endogenous IFN-γ as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi
Talvani, André, Ribeiro, Cristiana S, Aliberti, Júlio C.S, Michailowsky, Vladimir, Santos, Paula V.A, Murta, Silvane M.F, Romanha, Alvaro J, Almeida, Igor C, Farber, Joshua, Lannes-Vieira, Joseli, Silva, João S, Gazzinelli, Ricardo T
Published in Microbes and infection (01.07.2000)
Published in Microbes and infection (01.07.2000)
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β-Chemokines Enhance Parasite Uptake and Promote Nitric Oxide-Dependent Microbiostatic Activity in Murine Inflammatory Macrophages Infected with Trypanosoma cruzi
ALIBERTI, J. C. S, MACHADO, F. S, SOUTO, J. T, CAMPANELLI, A. P, TEIXEIRA, M. M, GAZZINELLI, R. T, SILVA, J. S
Published in Infection and Immunity (01.09.1999)
Published in Infection and Immunity (01.09.1999)
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IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity
Oswald, IP, Gazzinelli, RT, Sher, A, James, SL
Published in The Journal of immunology (1950) (01.06.1992)
Published in The Journal of immunology (1950) (01.06.1992)
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Journal Article
The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta
Gazzinelli, R T, Oswald, I P, Hieny, S, James, S L, Sher, A
Published in European journal of immunology (01.10.1992)
Published in European journal of immunology (01.10.1992)
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Biochemical characterization and protein kinase C dependency of monokine-inducing activities of Toxoplasma gondii
GRUNVALD, E, CHIARAMONTE, M, HIENY, S, WYSOCKA, M, TRINCHIERI, G, VOGEL, S. N, GAZZINELLI, R. T, SHER, A, MANSFIELD, J. M
Published in Infection and Immunity (01.06.1996)
Published in Infection and Immunity (01.06.1996)
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Journal Article
Defocusing microscopy
Agero, U., Mesquita, L.G., Neves, B.R.A., Gazzinelli, R.T., Mesquita, O.N.
Published in Microscopy research and technique (01.10.2004)
Published in Microscopy research and technique (01.10.2004)
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