Cost-effectiveness of Population-Based BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, PALB2 Mutation Testing in Unselected General Population Women
Manchanda, Ranjit, Patel, Shreeya, Gordeev, Vladimir S, Antoniou, Antonis C, Smith, Shantel, Lee, Andrew, Hopper, John L, MacInnis, Robert J, Turnbull, Clare, Ramus, Susan J, Gayther, Simon A, Pharoah, Paul D P, Menon, Usha, Jacobs, Ian, Legood, Rosa
Published in JNCI : Journal of the National Cancer Institute (01.07.2018)
Published in JNCI : Journal of the National Cancer Institute (01.07.2018)
Get full text
Journal Article
An epigenetic signature in peripheral blood predicts active ovarian cancer
Teschendorff, Andrew E, Menon, Usha, Gentry-Maharaj, Aleksandra, Ramus, Susan J, Gayther, Simon A, Apostolidou, Sophia, Jones, Allison, Lechner, Matthias, Beck, Stephan, Jacobs, Ian J, Widschwendter, Martin
Published in PloS one (18.12.2009)
Published in PloS one (18.12.2009)
Get full text
Journal Article
A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro
Myungjin Lee, Janet, Mhawech-Fauceglia, Paulette, Lee, Nathan, Cristina Parsanian, Lucineh, Gail Lin, Yvonne, Andrew Gayther, Simon, Lawrenson, Kate
Published in Laboratory investigation (01.05.2013)
Published in Laboratory investigation (01.05.2013)
Get full text
Journal Article
A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants
Gusev, Alexander, Lawrenson, Kate, Lin, Xianzhi, Lyra, Paulo C., Kar, Siddhartha, Vavra, Kevin C., Segato, Felipe, Fonseca, Marcos A. S., Lee, Janet M., Pejovic, Tanya, Liu, Gang, Karlan, Beth Y., Freedman, Matthew L., Noushmehr, Houtan, Monteiro, Alvaro N., Pharoah, Paul D. P., Pasaniuc, Bogdan, Gayther, Simon A.
Published in Nature genetics (01.05.2019)
Published in Nature genetics (01.05.2019)
Get full text
Journal Article
Genetic epidemiology of ovarian cancer and prospects for polygenic risk prediction
Jones, Michelle R., Kamara, Daniella, Karlan, Beth Y., Pharoah, Paul D.P., Gayther, Simon A.
Published in Gynecologic oncology (01.12.2017)
Published in Gynecologic oncology (01.12.2017)
Get full text
Journal Article
Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma
Chen, Li, Huang, Moli, Plummer, Jasmine, Pan, Jian, Jiang, Yan Yi, Yang, Qian, Silva, Tiago Chedraoui, Gull, Nicole, Chen, Stephanie, Ding, Ling Wen, An, Omer, Yang, Henry, Cheng, Yulan, Said, Jonathan W, Doan, Ngan, Dinjens, Winand NM, Waters, Kevin M, Tuli, Richard, Gayther, Simon A, Klempner, Samuel J, Berman, Benjamin P, Meltzer, Stephen J, Lin, De-Chen, Koeffler, H Phillip
Published in Gut (01.04.2020)
Published in Gut (01.04.2020)
Get full text
Journal Article
Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer
Ramus, Susan J, Song, Honglin, Dicks, Ed, Tyrer, Jonathan P, Rosenthal, Adam N, Intermaggio, Maria P, Fraser, Lindsay, Gentry-Maharaj, Aleksandra, Hayward, Jane, Philpott, Susan, Anderson, Christopher, Edlund, Christopher K, Conti, David, Harrington, Patricia, Barrowdale, Daniel, Bowtell, David D, Alsop, Kathryn, Mitchell, Gillian, Cicek, Mine S, Cunningham, Julie M, Fridley, Brooke L, Alsop, Jennifer, Jimenez-Linan, Mercedes, Poblete, Samantha, Lele, Shashi, Sucheston-Campbell, Lara, Moysich, Kirsten B, Sieh, Weiva, McGuire, Valerie, Lester, Jenny, Bogdanova, Natalia, Dürst, Matthias, Hillemanns, Peter, Odunsi, Kunle, Whittemore, Alice S, Karlan, Beth Y, Dörk, Thilo, Goode, Ellen L, Menon, Usha, Jacobs, Ian J, Antoniou, Antonis C, Pharoah, Paul D P, Gayther, Simon A
Published in JNCI : Journal of the National Cancer Institute (01.11.2015)
Published in JNCI : Journal of the National Cancer Institute (01.11.2015)
Get full text
Journal Article
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer
Teschendorff, Andrew E, Menon, Usha, Gentry-Maharaj, Aleksandra, Ramus, Susan J, Weisenberger, Daniel J, Shen, Hui, Campan, Mihaela, Noushmehr, Houtan, Bell, Christopher G, Maxwell, A Peter, Savage, David A, Mueller-Holzner, Elisabeth, Marth, Christian, Kocjan, Gabrijela, Gayther, Simon A, Jones, Allison, Beck, Stephan, Wagner, Wolfgang, Laird, Peter W, Jacobs, Ian J, Widschwendter, Martin
Published in Genome research (01.04.2010)
Published in Genome research (01.04.2010)
Get full text
Journal Article
The sex hormone system in carriers of BRCA1/2 mutations: a case-control study
Widschwendter, Martin, Prof, Rosenthal, Adam N, PhD, Philpott, Sue, MSc, Rizzuto, Ivana, MD, Fraser, Lindsay, BSc, Hayward, Jane, MSc, Intermaggio, Maria P, MSc, Edlund, Christopher K, MSc, Ramus, Susan J, PhD, Gayther, Simon A, Prof, Dubeau, Louis, Prof, Fourkala, Evangelia Ourania, PhD, Zaikin, Alexey, Prof, Menon, Usha, Prof, Jacobs, Ian J, Prof
Published in The lancet oncology (01.11.2013)
Published in The lancet oncology (01.11.2013)
Get full text
Journal Article
Principles for the post-GWAS functional characterization of cancer risk loci
Freedman, Matthew L, Monteiro, Alvaro N A, Gayther, Simon A, Coetzee, Gerhard A, Risch, Angela, Plass, Christoph, Casey, Graham, De Biasi, Mariella, Carlson, Chris, Duggan, David, James, Michael, Liu, Pengyuan, Tichelaar, Jay W, Vikis, Haris G, You, Ming, Mills, Ian G
Published in Nature genetics (01.06.2011)
Published in Nature genetics (01.06.2011)
Get full text
Journal Article
Lineage-specific epigenomic and genomic activation of oncogene HNF4A promotes gastrointestinal adenocarcinomas
Pan, Jian, Silva, Tiago C, Gull, Nicole, Yang, Qian, Plummer, Jasmine T, Chen, Stephanie, Daigo, Kenji, Hamakubo, Takao, Gery, Sigal, Ding, Ling-Wen, Jiang, Yan-Yi, Hu, Shaoyan, Xu, Li-Yan, Li, En-Min, Ding, Yanbing, Klempner, Samuel J, Gayther, Simon A, Berman, Benjamin P, Koeffler, H Phillip, Lin, De-Chen
Published in Cancer research (Chicago, Ill.) (01.07.2020)
Published in Cancer research (Chicago, Ill.) (01.07.2020)
Get full text
Journal Article
Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer
Corona, Rosario I., Seo, Ji-Heui, Lin, Xianzhi, Hazelett, Dennis J., Reddy, Jessica, Fonseca, Marcos A. S., Abassi, Forough, Lin, Yvonne G., Mhawech-Fauceglia, Paulette Y., Shah, Sohrab P., Huntsman, David G., Gusev, Alexander, Karlan, Beth Y., Berman, Benjamin P., Freedman, Matthew L., Gayther, Simon A., Lawrenson, Kate
Published in Nature communications (24.04.2020)
Published in Nature communications (24.04.2020)
Get full text
Journal Article
Molecular Analysis of Mixed Endometrioid and Serous Adenocarcinoma of the Endometrium
Lawrenson, Kate, Pakzamir, Elham, Liu, Biao, Lee, Janet M, Delgado, Melissa K, Duncan, Kara, Gayther, Simon A, Liu, Song, Roman, Lynda, Mhawech-Fauceglia, Paulette
Published in PloS one (01.07.2015)
Published in PloS one (01.07.2015)
Get full text
Journal Article
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
Mancuso, Nicholas, Gayther, Simon, Gusev, Alexander, Zheng, Wei, Penney, Kathryn L., Kote-Jarai, Zsofia, Eeles, Rosalind, Freedman, Matthew, Haiman, Christopher, Pasaniuc, Bogdan
Published in Nature communications (04.10.2018)
Published in Nature communications (04.10.2018)
Get full text
Journal Article
Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tube
Dinh, Huy Q., Lin, Xianzhi, Abbasi, Forough, Nameki, Robbin, Haro, Marcela, Olingy, Claire E., Chang, Heidi, Hernandez, Lourdes, Gayther, Simon A., Wright, Kelly N., Aspuria, Paul-Joseph, Karlan, Beth Y., Corona, Rosario I., Li, Andrew, Rimel, B.J., Siedhoff, Matthew T., Medeiros, Fabiola, Lawrenson, Kate
Published in Cell reports (Cambridge) (13.04.2021)
Published in Cell reports (Cambridge) (13.04.2021)
Get full text
Journal Article
GENAVi: a shiny web application for gene expression normalization, analysis and visualization
Reyes, Alberto Luiz P, Silva, Tiago C, Coetzee, Simon G, Plummer, Jasmine T, Davis, Brian D, Chen, Stephanie, Hazelett, Dennis J, Lawrenson, Kate, Berman, Benjamin P, Gayther, Simon A, Jones, Michelle R
Published in BMC genomics (16.10.2019)
Published in BMC genomics (16.10.2019)
Get full text
Journal Article
PAX8 expression in ovarian surface epithelial cells
Adler, Emily, BS, Mhawech-Fauceglia, Paulette, MD, Gayther, Simon A., PhD, Lawrenson, Kate, PhD
Published in Human pathology (01.07.2015)
Published in Human pathology (01.07.2015)
Get full text
Journal Article
Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis
Yucer, Nur, Ahdoot, Rodney, Workman, Michael J., Laperle, Alexander H., Recouvreux, Maria S., Kurowski, Kathleen, Naboulsi, Diana J., Liang, Victoria, Qu, Ying, Plummer, Jasmine T., Gayther, Simon A., Orsulic, Sandra, Karlan, Beth Y., Svendsen, Clive N.
Published in Cell reports (Cambridge) (28.12.2021)
Published in Cell reports (Cambridge) (28.12.2021)
Get full text
Journal Article