Cathepsin K inhibitors prevent bone loss in estrogen‐deficient rabbits
Pennypacker, Brenda L, Duong, Le T, Cusick, Tara E, Masarachia, Patricia J, Gentile, Michael A, Gauthier, Jacques‐Yves, Black, W Cameron, Scott, Boyd B, Samadfam, Rana, Smith, Susan Y, Kimmel, Donald B
Published in Journal of bone and mineral research (01.02.2011)
Published in Journal of bone and mineral research (01.02.2011)
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Protein Tyrosine Phosphatase-1B Dephosphorylation of the Insulin Receptor Occurs in a Perinuclear Endosome Compartment in Human Embryonic Kidney 293 Cells
Romsicki, Yolanda, Reece, Mark, Gauthier, Jacques-Yves, Asante-Appiah, Ernest, Kennedy, Brian P.
Published in The Journal of biological chemistry (26.03.2004)
Published in The Journal of biological chemistry (26.03.2004)
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Description of a 96-Well Plate Assay to Measure Cytochrome P4503A Inhibition in Human Liver Microsomes Using a Selective Fluorescent Probe
Chauret, Nathalie, Tremblay, Nathalie, Lackman, Rebecca L., Gauthier, Jacques-Yves, Silva, José M., Marois, Jean, Yergey, James A., Nicoll-Griffith, Deborah A.
Published in Analytical biochemistry (15.12.1999)
Published in Analytical biochemistry (15.12.1999)
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Applying the pro-drug approach to afford highly bioavailable antagonists of P2Y14
ROBICHAUD, Joel, FOURNIER, Jean-François, MANCINI, Joseph, MORIN, Nicolas, MULROONEY, Erin, JIN WU, BLACK, W. Cameron, GAGNE, Sébastien, YVES GAUTHIER, Jacques, HAMEL, Martine, YONGXIN HAN, HENAULT, Martin, KARGMAN, Stacia, LEVESQUE, Jean-François, MAMANE, Yaël
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
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The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14
YVES GAUTHIER, Jacques, BELLEY, Michel, LAVALLEE, Geneviève, LEVESQUE, Jean-François, LIANHAI LI, MAMANE, Yael, MANCINI, Joseph, MORIN, Nicolas, MULROONEY, Erin, ROBICHAUD, Joel, THERIEN, Michel, TRANMER, Geoffrey, DESCHENES, Denis, ZHAOYIN WANG, JIN WU, BLACK, W. Cameron, FOURNIER, Jean-François, GAGNE, Sébastien, GAREAU, Yves, HAMEL, Martine, HENAULT, Martin, HYJAZIE, Huda, KARGMAN, Stacia
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Selective isolation of in vitro phase II conjugates using a lipophilic anionic exchange solid phase extraction method
Gagné, Sébastien, Laterreur, Julie, Mahrouche, Louiza, Sørensen, Dan, Gauthier, Jacques Yves, Truong, Vouy Linh, Chauret, Nathalie, Lévesque, Jean-François
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.03.2008)
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Cyclooxygenase-2 Inhibitors. Synthesis and Pharmacological Activities of 5-Methanesulfonamido-1-indanone Derivatives
Li, Chun-Sing, Black, W. Cameron, Chan, Chi-Chung, Ford-Hutchinson, Anthony W, Gauthier, Jacques-Yves, Gordon, Robert, Guay, Daniel, Kargman, Stacia, Lau, Cheuk K
Published in Journal of medicinal chemistry (01.12.1995)
Published in Journal of medicinal chemistry (01.12.1995)
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Synthesis and biological evaluation of 3-heteroaryloxy-4-phenyl-2(5H)-furanones as selective COX-2 inhibitors
Lau, Cheuk K., Brideau, Christine, Chi Chung Chan, Charleson, Stella, Cromlish, Wanda A., Ethier, Diane, Gauthier, Jacques Yves, Gordon, Robert, Guay, Jocelyne, Kargman, Stacia, Li, Chun-Sing, Prasit, Petpiboon, Reindeau, Denis, Thérien, Michel, Visco, Denise M., Lijing Xu
Published in Bioorganic & medicinal chemistry letters (15.11.1999)
Published in Bioorganic & medicinal chemistry letters (15.11.1999)
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A new structural variation on the methanesulfonylphenyl class of selective cyclooxygenase-2 inhibitors
Li, Chun-Sing, Black, W.Cameron, Brideau, Christine, Chi Chung Chan, Charleson, Stella, Cromlish, Wanda A., Claveau, David, Gauthier, Jacques Yves, Gordon, Robert, Greig, Gillian, Grimm, Erich, Guay, Jocelyne, Lau, Cheuk K., Riendeau, Denis, Thérien, Michel, Visco, Denise M., Wong, Elizabeth, Lijing Xu, Prasit, Petpiboon
Published in Bioorganic & medicinal chemistry letters (15.11.1999)
Published in Bioorganic & medicinal chemistry letters (15.11.1999)
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The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K
Gauthier, Jacques Yves, Chauret, Nathalie, Cromlish, Wanda, Desmarais, Sylvie, Duong, Le T., Falgueyret, Jean-Pierre, Kimmel, Donald B., Lamontagne, Sonia, Léger, Serge, LeRiche, Tammy, Li, Chun Sing, Massé, Frédéric, McKay, Daniel J., Nicoll-Griffith, Deborah A., Oballa, Renata M., Palmer, James T., Percival, M. David, Riendeau, Denis, Robichaud, Joel, Rodan, Gideon A., Rodan, Sevgi B., Seto, Carmai, Thérien, Michel, Truong, Vouy-Linh, Venuti, Michael C., Wesolowski, Gregg, Young, Robert N., Zamboni, Robert, Black, W. Cameron
Published in Bioorganic & medicinal chemistry (01.02.2008)
Published in Bioorganic & medicinal chemistry (01.02.2008)
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Applying the pro-drug approach to afford highly bioavailable antagonists of P2Y
Robichaud, Joël, Fournier, Jean-François, Gagné, Sébastien, Gauthier, Jacques Yves, Hamel, Martine, Han, Yongxin, Hénault, Martin, Kargman, Stacia, Levesque, Jean-François, Mamane, Yaël, Mancini, Joseph, Morin, Nicolas, Mulrooney, Erin, Wu, Jin, Black, W. Cameron
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
Published in Bioorganic & medicinal chemistry letters (15.07.2011)
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AMINOPYRIMIDINES AS SYK INHIBITORS
DONOFRIO ANTHONY, GUAY DANIEL, DI FRANCESCO MARIA EMILIA, ZHOU HUA, CHILDERS KALEEN KONRAD, KNOWLES SANDRA LEE, SCHELL ADAM J, SPENCER KERRIE B, ALTMAN MICHAEL D, TAOKA BRANDON M, ANDRESEN BRIAN M, O'BOYLE BRENDAN M, GAUTHIER JACQUES YVES, REUTERSHAN MICHAEL H, HAIDLE ANDREW M, TROTTER B. WESLEY, OTTE RYAN D, GUERIN DAVID JOSEPH, BHAT SATHESH, PETROCCHI ALESSIA, SIU TONY, LI CHAOMIN, DUPONT GAUDET KRISTINA, MACHACEK MICHELLE R, WOO, HYUN CHONG, COTE BERNARD, GRIMM JONATHAN, ARRINGTON KENNETH L, ROBICHAUD JOEL S, KATTAR SOLOMON, MADDESS MATTHEW L, ROMEO ERIC, BURCH JASON, FOURNIER JEAN FRANCOIS, ELLIS JOHN MICHAEL, LIM, JONG WON, FISCHER CHRISTIAN, NORTHRUP ALAN B
Year of Publication 04.09.2012
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Year of Publication 04.09.2012
Patent
identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y
Gauthier, Jacques Yves, Belley, Michel, Deschênes, Denis, Fournier, Jean-François, Gagné, Sébastien, Gareau, Yves, Hamel, Martine, Hénault, Martin, Hyjazie, Huda, Kargman, Stacia, Lavallée, Geneviève, Levesque, Jean-François, Li, Lianhai, Mamane, Yaël, Mancini, Joseph, Morin, Nicolas, Mulrooney, Erin, Robichaud, Joël, Thérien, Michel, Tranmer, Geoffrey, Wang, Zhaoyin, Wu, Jin, Black, W. Cameron
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Probing cathepsin S activity in whole blood by the activity-based probe BIL-DMK: Cellular distribution in human leukocyte populations and evidence of diurnal modulation
Veilleux, Alain, Black, W. Cameron, Gauthier, Jacques Yves, Mellon, Christophe, Percival, M. David, Tawa, Paul, Falgueyret, Jean-Pierre
Published in Analytical biochemistry (01.04.2011)
Published in Analytical biochemistry (01.04.2011)
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Genetic and pharmacological evaluation of cathepsin s in a mouse model of asthma
Deschamps, Kathleen, Cromlish, Wanda, Weicker, Sean, Lamontagne, Sonia, Huszar, Sarah L, Gauthier, Jacques Yves, Mudgett, John S, Guimond, Alain, Romand, Raymond, Frossard, Nelly, Percival, M David, Slipetz, Deborah, Tan, Christopher M
Published in American journal of respiratory cell and molecular biology (01.07.2011)
Published in American journal of respiratory cell and molecular biology (01.07.2011)
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The identification of potent, selective, and bioavailable cathepsin S inhibitors
Gauthier, Jacques Yves, Black, W. Cameron, Courchesne, Isabelle, Cromlish, Wanda, Desmarais, Sylvie, Houle, Robert, Lamontagne, Sonia, Li, Chun Sing, Massé, Frédéric, McKay, Daniel J., Ouellet, Marc, Robichaud, Joël, Truchon, Jean-François, Truong, Vouy-Linh, Wang, Qingping, Percival, M. David
Published in Bioorganic & medicinal chemistry letters (01.09.2007)
Published in Bioorganic & medicinal chemistry letters (01.09.2007)
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Identification of a potent and selective non-basic cathepsin K inhibitor
Li, Chun Sing, Deschenes, Denis, Desmarais, Sylvie, Falgueyret, Jean-Pierre, Gauthier, Jacques Yves, Kimmel, Donald. B., Léger, Serge, Massé, Frédéric, McGrath, Mary E., McKay, Daniel J., Percival, M. David, Riendeau, Denis, Rodan, Sevgi B., Thérien, Michel, Truong, Vouy-Linh, Wesolowski, Gregg, Zamboni, Robert, Black, W. Cameron
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
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The Structural Basis for the Selectivity of Benzotriazole Inhibitors of PTP1B
Scapin, Giovanna, Patel, Sangita B, Becker, Joseph W, Wang, Qingping, Desponts, Caroline, Waddleton, Deena, Skorey, Kathryn, Cromlish, Wanda, Bayly, Christopher, Therien, Michel, Gauthier, Jacques Yves, Li, Chun Sing, Lau, Cheuk K, Ramachandran, Chidambaram, Kennedy, Brian P, Asante-Appiah, Ernest
Published in Biochemistry (Easton) (07.10.2003)
Published in Biochemistry (Easton) (07.10.2003)
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