2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
Blomme, Arnaud, Ford, Catriona A., Mui, Ernest, Patel, Rachana, Ntala, Chara, Jamieson, Lauren E., Planque, Mélanie, McGregor, Grace H., Peixoto, Paul, Hervouet, Eric, Nixon, Colin, Salji, Mark, Gaughan, Luke, Markert, Elke, Repiscak, Peter, Sumpton, David, Blanco, Giovanny Rodriguez, Lilla, Sergio, Kamphorst, Jurre J., Graham, Duncan, Faulds, Karen, MacKay, Gillian M., Fendt, Sarah-Maria, Zanivan, Sara, Leung, Hing Y.
Published in Nature communications (19.05.2020)
Published in Nature communications (19.05.2020)
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SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer
Martinez, Rafael S, Salji, Mark J, Rushworth, Linda, Ntala, Chara, Rodriguez Blanco, Giovanny, Hedley, Ann, Clark, William, Peixoto, Paul, Hervouet, Eric, Renaude, Elodie, Kung, Sonia H Y, Galbraith, Laura C A, Nixon, Colin, Lilla, Sergio, MacKay, Gillian M, Fazli, Ladan, Gaughan, Luke, Sumpton, David, Gleave, Martin E, Zanivan, Sara, Blomme, Arnaud, Leung, Hing Y
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer
Adamson, Beth, Brittain, Nicholas, Walker, Laura, Duncan, Ruaridh, Luzzi, Sara, Rescigno, Pasquale, Smith, Graham, McGill, Suzanne, Burchmore, Richard Js, Willmore, Elaine, Hickson, Ian, Robson, Craig N, Bogdan, Denisa, Jimenez-Vacas, Juan M, Paschalis, Alec, Welti, Jonathan, Yuan, Wei, McCracken, Stuart R, Heer, Rakesh, Sharp, Adam, de Bono, Johann S, Gaughan, Luke
Published in The Journal of clinical investigation (15.11.2023)
Published in The Journal of clinical investigation (15.11.2023)
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Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer
Jones, Dominic, Noble, Martin, Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Published in Scientific reports (16.02.2017)
Published in Scientific reports (16.02.2017)
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Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
Harris, Rebecca J., Heer, Maninder, Levasseur, Mark D., Cartwright, Tyrell N., Weston, Bethany, Mitchell, Jennifer L., Coxhead, Jonathan M., Gaughan, Luke, Prendergast, Lisa, Rico, Daniel, Higgins, Jonathan M. G.
Published in Nature communications (09.11.2023)
Published in Nature communications (09.11.2023)
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The RNA Helicase p68 Is a Novel Androgen Receptor Coactivator Involved in Splicing and Is Overexpressed in Prostate Cancer
CLARK, Emma L, COULSON, Anne, FULLER-PACE, Frances V, ROBSON, Craig N, DALGLIESH, Caroline, RAJAN, Prabhakar, NICOL, Samantha M, FLEMING, Stewart, HEER, Rakesh, GAUGHAN, Luke, LEUNG, Hing Y, ELLIOTT, David J
Published in Cancer research (Chicago, Ill.) (01.10.2008)
Published in Cancer research (Chicago, Ill.) (01.10.2008)
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Regulation of the androgen receptor by SET9-mediated methylation
Gaughan, Luke, Stockley, Jacqueline, Wang, Nan, McCracken, Stuart R.C, Treumann, Achim, Armstrong, Kelly, Shaheen, Fadhel, Watt, Kate, McEwan, Iain J, Wang, Chenguang, Pestell, Richard G, Robson, Craig N
Published in Nucleic acids research (01.03.2011)
Published in Nucleic acids research (01.03.2011)
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Identification of a novel K311 ubiquitination site critical for androgen receptor transcriptional activity
McClurg, Urszula L, Cork, David M W, Darby, Steven, Ryan-Munden, Claudia A, Nakjang, Sirintra, Mendes Côrtes, Leticia, Treumann, Achim, Gaughan, Luke, Robson, Craig N
Published in Nucleic acids research (28.02.2017)
Published in Nucleic acids research (28.02.2017)
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Propagation of human prostate tissue from induced pluripotent stem cells
Hepburn, Anastasia C., Curry, Emma L., Moad, Mohammad, Steele, Rebecca E., Franco, Omar E., Wilson, Laura, Singh, Parmveer, Buskin, Adriana, Crawford, Susan E., Gaughan, Luke, Mills, Ian G., Hayward, Simon W., Robson, Craig N., Heer, Rakesh
Published in Stem cells translational medicine (01.07.2020)
Published in Stem cells translational medicine (01.07.2020)
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Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity
Axon, Andrew, May, Felicity E.B, Gaughan, Luke E, Williams, Faith M, Blain, Peter G, Wright, Matthew C
Published in Toxicology (Amsterdam) (16.08.2012)
Published in Toxicology (Amsterdam) (16.08.2012)
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FUS/TLS Is a Novel Mediator of Androgen-Dependent Cell-Cycle Progression and Prostate Cancer Growth
BROOKE, Greg N, CULLEY, Rachel L, WAIT, Robin, WAXMAN, Jonathan, WALKER, Marjorie M, BEVAN, Charlotte L, DART, D. Alwyn, MANN, David J, GAUGHAN, Luke, MCCRACKEN, Stuart R, ROBSON, Craig N, SPENCER-DENE, Bradley, GAMBLE, Simon C, POWELL, Sue M
Published in Cancer research (Chicago, Ill.) (01.02.2011)
Published in Cancer research (Chicago, Ill.) (01.02.2011)
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SETD6 controls the expression of estrogen-responsive genes and proliferation of breast carcinoma cells
O'Neill, Daniel J, Williamson, Stuart Charles, Alkharaif, Dhuha, Monteiro, Isabella Christina Mazzaro, Goudreault, Marilyn, Gaughan, Luke, Robson, Craig N, Gingras, Anne-Claude, Binda, Olivier
Published in Epigenetics (01.07.2014)
Published in Epigenetics (01.07.2014)
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ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer
Garnham, Rebecca, Geh, Daniel, Nelson, Ryan, Ramon-Gil, Erik, Wilson, Laura, Schmidt, Edward N., Walker, Laura, Adamson, Beth, Buskin, Adriana, Hepburn, Anastasia C., Hodgson, Kirsty, Kendall, Hannah, Frame, Fiona M., Maitland, Norman, Coffey, Kelly, Strand, Douglas W., Robson, Craig N., Elliott, David J., Heer, Rakesh, Macauley, Matthew, Munkley, Jennifer, Gaughan, Luke, Leslie, Jack, Scott, Emma
Published in Communications biology (06.03.2024)
Published in Communications biology (06.03.2024)
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Targeting the DNA double strand break repair machinery in prostate cancer
Shaheen, Fadhel S, Znojek, Pawel, Fisher, Ann, Webster, Martin, Plummer, Ruth, Gaughan, Luke, Smith, Graeme C M, Leung, Hing Y, Curtin, Nicola J, Robson, Craig N
Published in PloS one (23.05.2011)
Published in PloS one (23.05.2011)
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Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome
Rajan, Prabhakar, Dalgliesh, Caroline, Carling, Phillippa J, Buist, Thomas, Zhang, Chaolin, Grellscheid, Sushma N, Armstrong, Kelly, Stockley, Jacqueline, Simillion, Cedric, Gaughan, Luke, Kalna, Gabriela, Zhang, Michael Q, Robson, Craig N, Leung, Hing Y, Elliott, David J
Published in PloS one (14.12.2011)
Published in PloS one (14.12.2011)
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Human PIRH2 Enhances Androgen Receptor Signaling through Inhibition of Histone Deacetylase 1 and Is Overexpressed in Prostate Cancer
Logan, Ian R., Gaughan, Luke, McCracken, Stuart R. C., Sapountzi, Vasileia, Leung, Hing Y., Robson, Craig N.
Published in Molecular and Cellular Biology (01.09.2006)
Published in Molecular and Cellular Biology (01.09.2006)
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Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer
McClurg, Urszula L, Harle, Victoria J, Nabbi, Arash, Batalha-Pereira, Amanda, Walker, Scott, Coffey, Kelly, Gaughan, Luke, McCracken, Stuart R C, Robson, Craig N
Published in Oncotarget (10.11.2015)
Published in Oncotarget (10.11.2015)
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FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer
Jones, Dominic, Wade, Mark, Nakjang, Sirintra, Chaytor, Lewis, Grey, James, Robson, Craig N., Gaughan, Luke
Published in Oncotarget (06.10.2015)
Published in Oncotarget (06.10.2015)
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