Search Results - "GASTALDI, SIMONE" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Chemical Modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazole-2-one Scaffold as a Novel NLRP3 Inhibitor

Chemical Modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazole-2-one Scaffold as a Novel NLRP3 Inhibitor

by Gastaldi, Simone, Boscaro, Valentina, Gianquinto, Eleonora, Sandall, Christina F., Giorgis, Marta, Marini, Elisabetta, Blua, Federica, Gallicchio, Margherita, Spyrakis, Francesca, MacDonald, Justin A., Bertinaria, Massimo
Published in Molecules (Basel, Switzerland) (29.06.2021)

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Journal Article

Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E Protein

Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E Protein

by Marini, Elisabetta, Marino, Marco, Gionfriddo, Giulia, Maione, Federica, Pandini, Marta, Oddo, Daniele, Giorgis, Marta, Rolando, Barbara, Blua, Federica, Gastaldi, Simone, Marchiò, Serena, Kovachka, Sandra, Spyrakis, Francesca, Gianquinto, Eleonora, Di Nicolantonio, Federica, Bertinaria, Massimo
Published in Molecules (Basel, Switzerland) (03.12.2022)

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Journal Article

A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation

A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation

by Pellegrini, Carolina, Fornai, Matteo, Colucci, Rocchina, Benvenuti, Laura, D’Antongiovanni, Vanessa, Natale, Gianfranco, Fulceri, Federica, Giorgis, Marta, Marini, Elisabetta, Gastaldi, Simone, Bertinaria, Massimo, Blandizzi, Corrado, Antonioli, Luca
Published in Frontiers in pharmacology (03.12.2018)

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Journal Article

Development of covalent NLRP3 inflammasome inhibitors: Chemistry and biological activity

Development of covalent NLRP3 inflammasome inhibitors: Chemistry and biological activity

by Bertinaria, Massimo, Gastaldi, Simone, Marini, Elisabetta, Giorgis, Marta
Published in Archives of biochemistry and biophysics (30.07.2019)

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Journal Article

Cardioprotective effects of novel NLRP3 inflammasome inhibitors

Cardioprotective effects of novel NLRP3 inflammasome inhibitors

by Comità, Stefano, Pagliaro, Pasquale, Penna, Claudia, Bertinaria, Massimo, Spyrakis, Francesca, Gastaldi, Simone, Boscaro, Valentina, Gianquinto, Eleonora
Published in Journal of molecular and cellular cardiology (31.12.2022)

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Journal Article

Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation

Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation

by Gastaldi, Simone, Rocca, Carmine, Gianquinto, Eleonora, Granieri, Maria Concetta, Boscaro, Valentina, Blua, Federica, Rolando, Barbara, Marini, Elisabetta, Gallicchio, Margherita, De Bartolo, Anna, Romeo, Naomi, Mazza, Rosa, Fedele, Francesco, Pagliaro, Pasquale, Penna, Claudia, Spyrakis, Francesca, Bertinaria, Massimo, Angelone, Tommaso
Published in European journal of medicinal chemistry (05.09.2023)

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Journal Article

Novel NLRP3 inhibitor INF195: Low doses provide effective protection against myocardial ischemia/reperfusion injury

Novel NLRP3 inhibitor INF195: Low doses provide effective protection against myocardial ischemia/reperfusion injury

by Gastaldi, Simone, Giordano, Magalì, Blua, Federica, Rubeo, Chiara, Boscaro, Valentina, Femminò, Saveria, Comità, Stefano, Gianquinto, Eleonora, Landolfi, Vanessa, Marini, Elisabetta, Gallicchio, Margherita, Spyrakis, Francesca, Pagliaro, Pasquale, Bertinaria, Massimo, Penna, Claudia
Published in Vascular pharmacology (01.09.2024)

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Journal Article

Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF[sup.V600E] Protein

Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF[sup.V600E] Protein

by Marini, Elisabetta, Marino, Marco, Gionfriddo, Giulia, Maione, Federica, Pandini, Marta, Oddo, Daniele, Giorgis, Marta, Rolando, Barbara, Blua, Federica, Gastaldi, Simone, Marchiò, Serena, Kovachka, Sandra, Spyrakis, Francesca, Gianquinto, Eleonora, Di Nicolantonio, Federica, Be
Published in Molecules (Basel, Switzerland) (01.12.2022)

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Journal Article

657: GUT-DIRECTED LOCALLY ACTING NLRP3 INFLAMMASOME INHIBITOR AS A SUITABLE PHARMACOLOGICAL STRATEGY TARGETING GUT-BRAIN AXIS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

657: GUT-DIRECTED LOCALLY ACTING NLRP3 INFLAMMASOME INHIBITOR AS A SUITABLE PHARMACOLOGICAL STRATEGY TARGETING GUT-BRAIN AXIS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

by Pellegrini, Carolina, Colucci, Rocchina, Benvenuti, Laura, D'Antongiovanni, Vanessa, Salvo, Clelia Di, Gastaldi, Simone, Blua, Federica, Marini, Elisabetta, Rolando, Barbara, Lazzarato, Loretta, Bernardini, Nunzia, Antonioli, Luca, Bertinaria, Massimo, Fornai, Matteo
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)

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Discovery of a septin-4 covalent binder with antimetastatic activity in a mouse model of melanoma

Discovery of a septin-4 covalent binder with antimetastatic activity in a mouse model of melanoma

by Blua, Federica, Monge, Chiara, Gastaldi, Simone, Clemente, Nausicaa, Pizzimenti, Stefania, Lazzarato, Loretta, Senetta, Rebecca, Vittorio, Serena, Gigliotti, Casimiro Luca, Boggio, Elena, Dianzani, Umberto, Vistoli, Giulio, Altomare, Alessandra Anna, Aldini, Giancarlo, Dianzani, Chiara, Marini, Elisabetta, Bertinaria, Massimo
Published in Bioorganic chemistry (01.03.2024)

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Journal Article

Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF V600E Protein

Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAF V600E Protein

by Marini, Elisabetta, Marino, Marco, Gionfriddo, Giulia, Maione, Federica, Pandini, Marta, Oddo, Daniele, Giorgis, Marta, Rolando, Barbara, Blua, Federica, Gastaldi, Simone, Marchiò, Serena, Kovachka, Sandra, Spyrakis, Francesca, Gianquinto, Eleonora, Di Nicolantonio, Federica, Bertinaria, Massimo
Published in Molecules (Basel, Switzerland) (03.12.2022)

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Journal Article

Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation

Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation

by Gastaldi, Simone, Rocca, Carmine, Gianquinto, Eleonora, Granieri, Maria Concetta, Boscaro, Valentina, Blua, Federica, Rolando, Barbara, Marini, Elisabetta, Gallicchio, Margherita, De Bartolo, Anna, Romeo, Naomi, Mazza, Rosa, Fedele, Francesco, Pagliaro, Pasquale, Penna, Claudia, Spyrakis, Francesca, Bertinaria, Massimo, Angelone, Tommaso
Year of Publication 14.09.2023

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Journal Article

NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF

NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF

by Boscaro, Valentina, Antonioli, Luca, Blandizzi, Corrado, Pellegrini, Carolina, Colucci, Rocchina, Cocco, Mattia, Gastaldi, Simone, Fornai, Matteo, Marini, Elisabetta, Bertinaria, Massimo
Year of Publication 01.08.2024

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Patent

NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF

NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF

by MARINI, Elisabetta, COCCO, Mattia, GASTALDI, Simone, FORNAI, Matteo, BOSCARO, Valentina, PELLEGRINI, Carolina, ANTONIOLI, Luca, COLUCCI, Rocchina, BERTINARIA, Massimo
Year of Publication 13.03.2024

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Patent

NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF

NLRP3 INFLAMMASOME-INHIBITING COMPOUNDS AND THE USE THEREOF

by MARINI, Elisabetta, COCCO, Mattia, GASTALDI, Simone, FORNAI, Matteo, BOSCARO, Valentina, PELLEGRINI, Carolina, ANTONIOLI, Luca, BLANDIZZI, Corrado, COLUCCI, Rocchina, BERTINARIA, Massimo
Year of Publication 10.11.2022

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Patent

COMPOSTI INIBITORI DELL'INFLAMMASOMA NLRP3 E LORO USO

COMPOSTI INIBITORI DELL'INFLAMMASOMA NLRP3 E LORO USO

by MARINI, ELISABETTA, PELLEGRINI, CAROLINA, BOSCARO, VALENTINA, GASTALDI, SIMONE, ANTONIOLI, LUCA, BERTINARIA, MASSIMO, COLUCCI, ROCCHINA, BLANDIZZI, CORRADO, COCCO, MATTIA, FORNAI, MATTEO
Year of Publication 03.11.2022

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Patent

Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation

Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation

by Gastaldi, Simone, Rocca, Carmine, Gianquinto, Eleonora, Granieri, Maria Concetta, Boscaro, Valentina, Blua, Federica, Rolando, Barbara, Marini, Elisabetta, Gallicchio, Margherita, De Bartolo, Anna, Romeo, Naomi, Mazza, Rosa, Fedele, Francesco, Pagliaro, Pasquale, Penna, Claudia, Spyrakis, Francesca, Bertinaria, Massimo, Angelone, Tommaso
Published in arXiv.org (14.09.2023)

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Paper

Arched plant protector with adjustable cover

Arched plant protector with adjustable cover

by GASTALDI RANTZ SIMONE CATHERINE, RANTZ LOUIS MICHEL
Year of Publication 25.06.1986

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Patent

DISPOSITIVO PER SCOPRIRE EDIFICI COME AD ESEMPIO SERRE A COPERTURA, IN PARTICOLARE DI FILM PLASTICO

DISPOSITIVO PER SCOPRIRE EDIFICI COME AD ESEMPIO SERRE A COPERTURA, IN PARTICOLARE DI FILM PLASTICO

by GASTALDI RANTZ SIMONE CATHERINE, RANTZ LOUIS MICHEL
Year of Publication 24.01.1980

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Patent