Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer
Duncan, James S., Whittle, Martin C., Nakamura, Kazuhiro, Abell, Amy N., Midland, Alicia A., Zawistowski, Jon S., Johnson, Nancy L., Granger, Deborah A., Jordan, Nicole Vincent, Darr, David B., Usary, Jerry, Kuan, Pei-Fen, Smalley, David M., Major, Ben, He, Xiaping, Hoadley, Katherine A., Zhou, Bing, Sharpless, Norman E., Perou, Charles M., Kim, William Y., Gomez, Shawn M., Chen, Xin, Jin, Jian, Frye, Stephen V., Earp, H. Shelton, Graves, Lee M., Johnson, Gary L.
Published in Cell (13.04.2012)
Published in Cell (13.04.2012)
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Coordination of Rho GTPase activities during cell protrusion
Welch, Christopher, Elliott, Hunter, Johnson, Gary L, Nalbant, Perihan, Hodgson, Louis, Pertz, Olivier, Danuser, Gaudenz, Abell, Amy, Hahn, Klaus M, Machacek, Matthias
Published in Nature (London) (03.09.2009)
Published in Nature (London) (03.09.2009)
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The dynamic nature of the kinome
Graves, Lee M, Duncan, James S, Whittle, Martin C, Johnson, Gary L
Published in Biochemical journal (15.02.2013)
Published in Biochemical journal (15.02.2013)
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Inhibition of Lapatinib-induced Kinome Reprogramming in ERBB2-positive Breast Cancer by Targeting BET Family Bromodomains
Stuhlmiller, Timothy J., Miller, Samantha M., Zawistowski, Jon S., Nakamura, Kazuhiro, Beltran, Adriana S., Duncan, James S., Angus, Steven P., Collins, Kyla A.L, Granger, Deborah A., Reuther, Rachel A., Graves, Lee M., Gomez, Shawn M., Kuan, Pei-Fen, Parker, Joel S., Chen, Xin, Sciaky, Noah, Carey, Lisa A., Earp, H. Shelton, Jin, Jian, Johnson, Gary L.
Published in Cell reports (Cambridge) (21.04.2015)
Published in Cell reports (Cambridge) (21.04.2015)
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New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging
Brighton, Hailey E, Angus, Steven P, Bo, Tao, Roques, Jose, Tagliatela, Alicia C, Darr, David B, Karagoz, Kubra, Sciaky, Noah, Gatza, Michael L, Sharpless, Norman E, Johnson, Gary L, Bear, James E
Published in Cancer research (Chicago, Ill.) (15.01.2018)
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MAP3K4/CBP-Regulated H2B Acetylation Controls Epithelial-Mesenchymal Transition in Trophoblast Stem Cells
Abell, Amy N., Jordan, Nicole Vincent, Huang, Weichun, Prat, Aleix, Midland, Alicia A., Johnson, Nancy L., Granger, Deborah A., Mieczkowski, Piotr A., Perou, Charles M., Gomez, Shawn M., Li, Leping, Johnson, Gary L.
Published in Cell stem cell (06.05.2011)
Published in Cell stem cell (06.05.2011)
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Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in Chordoma
Asquith, Christopher R. M, Naegeli, Kaleb M, East, Michael P, Laitinen, Tuomo, Havener, Tammy M, Wells, Carrow I, Johnson, Gary L, Drewry, David H, Zuercher, William J, Morris, David C
Published in Journal of medicinal chemistry (09.05.2019)
Published in Journal of medicinal chemistry (09.05.2019)
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MAP3K4 Controls the Chromatin Modifier HDAC6 during Trophoblast Stem Cell Epithelial-to-Mesenchymal Transition
Mobley, Robert J., Raghu, Deepthi, Duke, Lauren D., Abell-Hart, Kayley, Zawistowski, Jon S., Lutz, Kyla, Gomez, Shawn M., Roy, Sujoy, Homayouni, Ramin, Johnson, Gary L., Abell, Amy N.
Published in Cell reports (Cambridge) (07.03.2017)
Published in Cell reports (Cambridge) (07.03.2017)
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Rho Kinase Inhibition Rescues the Endothelial Cell Cerebral Cavernous Malformation Phenotype
Borikova, Asya L., Dibble, Christopher F., Sciaky, Noah, Welch, Christopher M., Abell, Amy N., Bencharit, Sompop, Johnson, Gary L.
Published in The Journal of biological chemistry (16.04.2010)
Published in The Journal of biological chemistry (16.04.2010)
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Limited inhibition of multiple nodes in a driver network blocks metastasis
Yesilkanal, Ali Ekrem, Yang, Dongbo, Valdespino, Andrea, Tiwari, Payal, Sabino, Alan U, Nguyen, Long Chi, Lee, Jiyoung, Xie, Xiao-He, Sun, Siqi, Dann, Christopher, Robinson-Mailman, Lydia, Steinberg, Ethan, Stuhlmiller, Timothy, Frankenberger, Casey, Goldsmith, Elizabeth, Johnson, Gary L, Ramos, Alexandre F, Rosner, Marsha R
Published in eLife (11.05.2021)
Published in eLife (11.05.2021)
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High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy
Cheng, Chialin, Reis, Surya A., Adams, Emily T., Fass, Daniel M., Angus, Steven P., Stuhlmiller, Timothy J., Richardson, Jared, Olafson, Hailey, Wang, Eric T., Patnaik, Debasis, Beauchamp, Roberta L., Feldman, Danielle A., Silva, M. Catarina, Sur, Mriganka, Johnson, Gary L., Ramesh, Vijaya, Miller, Bruce L., Temple, Sally, Kosik, Kenneth S., Dickerson, Bradford C., Haggarty, Stephen J.
Published in Scientific reports (23.08.2021)
Published in Scientific reports (23.08.2021)
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Neratinib, a pan ERBB/HER inhibitor, restores sensitivity of PTEN -null, BRAFV600E melanoma to BRAF/MEK inhibition
DuBose, Evan, Bevill, Samantha M, Mitchell, Dana K, Sciaky, Noah, Golitz, Brian T, Dixon, Shelley A H, Rhodes, Steven D, Bear, James E, Johnson, Gary L, Angus, Steven P
Published in Frontiers in oncology (16.05.2024)
Published in Frontiers in oncology (16.05.2024)
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SWI/SNF Chromatin-Remodeling Factor Smarcd3/Baf60c Controls Epithelial-Mesenchymal Transition by Inducing Wnt5a Signaling
Jordan, Nicole Vincent, Prat, Aleix, Abell, Amy N., Zawistowski, Jon S., Sciaky, Noah, Karginova, Olga A., Zhou, Bingying, Golitz, Brian T., Perou, Charles M., Johnson, Gary L.
Published in Molecular and Cellular Biology (01.08.2013)
Published in Molecular and Cellular Biology (01.08.2013)
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Identification and Optimization of 4‐Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase
Asquith, Christopher R. M., Laitinen, Tuomo, Bennett, James M., Godoi, Paulo H., East, Michael P., Tizzard, Graham J., Graves, Lee M., Johnson, Gary L., Dornsife, Ronna E., Wells, Carrow I., Elkins, Jonathan M., Willson, Timothy M., Zuercher, William J.
Published in ChemMedChem (08.01.2018)
Published in ChemMedChem (08.01.2018)
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