Combining functional and structural genomics to sample the essential Burkholderia structome
Baugh, Loren, Gallagher, Larry A, Patrapuvich, Rapatbhorn, Clifton, Matthew C, Gardberg, Anna S, Edwards, Thomas E, Armour, Brianna, Begley, Darren W, Dieterich, Shellie H, Dranow, David M, Abendroth, Jan, Fairman, James W, Fox, 3rd, David, Staker, Bart L, Phan, Isabelle, Gillespie, Angela, Choi, Ryan, Nakazawa-Hewitt, Steve, Nguyen, Mary Trang, Napuli, Alberto, Barrett, Lynn, Buchko, Garry W, Stacy, Robin, Myler, Peter J, Stewart, Lance J, Manoil, Colin, Van Voorhis, Wesley C
Published in PloS one (31.01.2013)
Published in PloS one (31.01.2013)
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Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor
Wilson, Jonathan E., Patel, Gaurav, Patel, Chirag, Brucelle, Francois, Huhn, Annissa, Gardberg, Anna S., Poy, Florence, Cantone, Nico, Bommi-Reddy, Archana, Sims, Robert J., Cummings, Richard T., Levell, Julian R.
Published in ACS medicinal chemistry letters (11.06.2020)
Published in ACS medicinal chemistry letters (11.06.2020)
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Increasing the structural coverage of tuberculosis drug targets
Baugh, Loren, Phan, Isabelle, Begley, Darren W, Clifton, Matthew C, Armour, Brianna, Dranow, David M, Taylor, Brandy M, Muruthi, Marvin M, Abendroth, Jan, Fairman, James W, Fox, David, Dieterich, Shellie H, Staker, Bart L, Gardberg, Anna S, Choi, Ryan, Hewitt, Stephen N, Napuli, Alberto J, Myers, Janette, Barrett, Lynn K, Zhang, Yang, Ferrell, Micah, Mundt, Elizabeth, Thompkins, Katie, Tran, Ngoc, Lyons-Abbott, Sally, Abramov, Ariel, Sekar, Aarthi, Serbzhinskiy, Dmitri, Lorimer, Don, Buchko, Garry W, Stacy, Robin, Stewart, Lance J, Edwards, Thomas E, Van Voorhis, Wesley C, Myler, Peter J
Published in Tuberculosis (Edinburgh, Scotland) (01.03.2015)
Published in Tuberculosis (Edinburgh, Scotland) (01.03.2015)
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Journal Article
Early Drug‐Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors
Huhn, Annissa J., Gardberg, Anna S., Poy, Florence, Brucelle, Francois, Vivat, Valerie, Cantone, Nico, Patel, Gaurav, Patel, Chirag, Cummings, Richard, Sims, Robert, Levell, Julian, Audia, James E., Bommi‐Reddy, Archana, Wilson, Jonathan E.
Published in ChemMedChem (04.06.2020)
Published in ChemMedChem (04.06.2020)
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Journal Article
Molecular basis for passive immunotherapy of Alzheimer's disease
Gardberg, Anna S, Dice, Lezlee T, Ou, Susan, Rich, Rebecca L, Helmbrecht, Elizabeth, Ko, Jan, Wetzel, Ronald, Myszka, David G, Patterson, Paul H, Dealwis, Chris
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2007)
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Journal Article
Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases
Caldwell, Richard D, Qiu, Hui, Askew, Ben C, Bender, Andrew T, Brugger, Nadia, Camps, Montserrat, Dhanabal, Mohanraj, Dutt, Vikram, Eichhorn, Thomas, Gardberg, Anna S, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Healey, Brian, Hodous, Brian L, Huck, Bayard R, Johnson, Theresa L, Jones, Christopher, Jones, Reinaldo C, Mochalkin, Igor, Morandi, Federica, Nguyen, Ngan, Meyring, Michael, Potnick, Justin R, Santos, Dusica Cvetinovic, Schmidt, Ralf, Sherer, Brian, Shutes, Adam, Urbahns, Klaus, Follis, Ariele Viacava, Wegener, Ansgar A, Zimmerli, Simone C, Liu-Bujalski, Lesley
Published in Journal of medicinal chemistry (12.09.2019)
Published in Journal of medicinal chemistry (12.09.2019)
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Journal Article
Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinone
Aoyagi-Scharber, Mika, Gardberg, Anna S., Yip, Bryan K., Wang, Bing, Shen, Yuqiao, Fitzpatrick, Paul A.
Published in Acta crystallographica. Section F, Structural biology communications (01.09.2014)
Published in Acta crystallographica. Section F, Structural biology communications (01.09.2014)
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Journal Article
NMR-guided refinement of crystal structures using 15N chemical shift tensors
Toomey, Ryan, Wang, Luther, Heider, Emily C, Hartman, Joshua D, Nichols, Alexander J, Myles, Dean A A, Gardberg, Anna S, McIntyre, Garry J, Zeller, Matthias, Mehta, Manish A, Harper, James K
Published in CrystEngComm (24.06.2024)
Published in CrystEngComm (24.06.2024)
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Journal Article
Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors
Haft, Daniel H., Pierce, Phillip G., Mayclin, Stephen J., Sullivan, Amy, Gardberg, Anna S., Abendroth, Jan, Begley, Darren W., Phan, Isabelle Q., Staker, Bart L., Myler, Peter J., Marathias, Vasilios M., Lorimer, Donald D., Edwards, Thomas E.
Published in Scientific reports (25.01.2017)
Published in Scientific reports (25.01.2017)
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Journal Article
Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D
Zhang, Yanfeng, Gardberg, Anna S., Edwards, Thomas E., Sankaran, Banumathi, Robinson, Howard, Varnum, Susan M., Buchko, Garry W.
Published in Biochimie (01.07.2013)
Published in Biochimie (01.07.2013)
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Journal Article
Make the right measurement: Discovery of an allosteric inhibition site for p300-HAT
Gardberg, Anna S., Huhn, Annissa J., Cummings, Richard, Bommi-Reddy, Archana, Poy, Florence, Setser, Jeremy, Vivat, Valerie, Brucelle, Francois, Wilson, Jonathan
Published in Structural dynamics (Melville, N.Y.) (01.09.2019)
Published in Structural dynamics (Melville, N.Y.) (01.09.2019)
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Journal Article
765 The first-in-class small molecule TREX1 inhibitor CPI-381 demonstrates type I IFN induction and sensitization of tumors to immune checkpoint blockade
Salojin, Costa, Gardberg, Anna, Vivat, Valerie, Cui, Lei, Lauer, Jeffrey, Cantone, Nico, Stuckey, Jacob, Poy, Florence, Almeciga, Ingrid, Cummings, Richard, Wilson, Jonathan, Levell, Julian, Rocnik, Jennifer, Trojer, Patrick
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Unambiguous determination of H-atom positions: comparing results from neutron and high-resolution X-ray crystallography
Gardberg, Anna S., Del Castillo, Alexis Rae, Weiss, Kevin L., Meilleur, Flora, Blakeley, Matthew P., Myles, Dean A. A.
Published in Acta crystallographica. Section D, Biological crystallography. (01.05.2010)
Published in Acta crystallographica. Section D, Biological crystallography. (01.05.2010)
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Journal Article
Crystal Structure of Toxoplasma gondii Porphobilinogen Synthase
Jaffe, Eileen K., Shanmugam, Dhanasekaran, Gardberg, Anna, Dieterich, Shellie, Sankaran, Banumathi, Stewart, Lance J., Myler, Peter J., Roos, David S.
Published in The Journal of biological chemistry (01.04.2011)
Published in The Journal of biological chemistry (01.04.2011)
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Journal Article
SAD phasing using iodide ions in a high-throughput structural genomics environment
Abendroth, Jan, Gardberg, Anna S., Robinson, John I., Christensen, Jeff S., Staker, Bart L., Myler, Peter J., Stewart, Lance J., Edwards, Thomas E.
Published in Journal of structural and functional genomics (01.07.2011)
Published in Journal of structural and functional genomics (01.07.2011)
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Journal Article
Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis
Edwards, Thomas E, Abramov, Ariel B, Smith, Eric R, Baydo, Ruth O, Leonard, Jess T, Leibly, David J, Thompkins, Kaitlin B, Clifton, Matthew C, Gardberg, Anna S, Staker, Bart L, Van Voorhis, Wesley C, Myler, Peter J, Stewart, Lance J
Published in BMC structural biology (13.10.2011)
Published in BMC structural biology (13.10.2011)
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Journal Article
Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP
Lorimer, Donald D., Choi, Ryan, Abramov, Ariel, Nakazawa Hewitt, Stephen, Gardberg, Anna S., Van Voorhis, Wesley C., Staker, Bart L., Myler, Peter J., Edwards, Thomas E.
Published in Acta crystallographica. Section F, Structural biology communications (01.05.2015)
Published in Acta crystallographica. Section F, Structural biology communications (01.05.2015)
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Journal Article
Structure of uridine diphosphate N-acetylglucosamine pyrophosphorylase from Entamoeba histolytica
Edwards, Thomas E., Gardberg, Anna S., Phan, Isabelle Q. H., Zhang, Yang, Staker, Bart L., Myler, Peter J., Lorimer, Donald D.
Published in Acta crystallographica. Section F, Structural biology communications (01.05.2015)
Published in Acta crystallographica. Section F, Structural biology communications (01.05.2015)
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