Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors
Rudinskiy, Mikhail, Pons-Vizcarra, Maria, Soldà, Tatiana, Fregno, Ilaria, Bergmann, Timothy Jan, Ruano, Ana, Delgado, Aida, Morales, Sara, Barril, Xavier, Bellotto, Manolo, Cubero, Elena, García-Collazo, Ana María, Pérez-Carmona, Natalia, Molinari, Maurizio
Published in PloS one (29.11.2023)
Published in PloS one (29.11.2023)
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Journal Article
Synthesis of [1,2,4]-triazolo[1,5- a]pyrimidines by Dimroth rearrangement of [1,2,4]-triazolo[4,3- a]pyrimidines: A theoretical and NMR study
Salgado, Antonio, Varela, Carmen, García Collazo, Ana María, García, Fernando, Pevarello, Paolo, Alkorta, Ibon, Elguero, José
Published in Journal of molecular structure (22.02.2011)
Published in Journal of molecular structure (22.02.2011)
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Journal Article
Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I
Cubero, Elena, Ruano, Ana, Delgado, Aida, Barril, Xavier, Morales, Sara, Trapero, Ana, Leoni, Lorenzo, Bellotto, Manolo, Maj, Roberto, Guzmán, Beatriz Calvo-Flores, Pérez-Carmona, Natalia, Garcia-Collazo, Ana Maria
Published in PloS one (20.05.2024)
Published in PloS one (20.05.2024)
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Journal Article
Thyroid receptor ligands. Part 5: Novel bicyclic agonist ligands selective for the thyroid hormone receptor β
Garcia Collazo, Ana-Maria, Koehler, Konrad F., Garg, Neeraj, Färnegårdh, Mathias, Husman, Bolette, Ye, Liu, Ljunggren, Jan, Mellström, Karin, Sandberg, Johnny, Grynfarb, Marlena, Ahola, Harri, Malm, Johan
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Journal Article
Differentiation between [1,2,4]triazolo[1,5-a] pyrimidine and [1,2,4]triazolo[4,3-a]- pyrimidine regioisomers by 1H15N HMBC experiments
Salgado, Antonio, Varela, Carmen, García Collazo, Ana María, Pevarello, Paolo
Published in Magnetic resonance in chemistry (01.08.2010)
Published in Magnetic resonance in chemistry (01.08.2010)
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Journal Article
Pim 1 kinase inhibitor ETP-45299 suppresses cellular proliferation and synergizes with PI3K inhibition
Blanco-Aparicio, Carmen, Collazo, Ana María García, Oyarzabal, Julen, Leal, Juan F, Albarán, María Isabel, Lima, Francisco Ramos, Pequeño, Belén, Ajenjo, Nuria, Becerra, Mercedes, Alfonso, Patricia, Reymundo, María Isabel, Palacios, Irene, Mateos, Genoveva, Quiñones, Helena, Corrionero, Ana, Carnero, Amancio, Pevarello, Paolo, Lopez, Ana Rodríguez, Fominaya, Jesús, Pastor, Joaquín, Bischoff, James R
Published in Cancer letters (28.01.2011)
Published in Cancer letters (28.01.2011)
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Journal Article
Thyroid Receptor Ligands. 1. Agonist Ligands Selective for the Thyroid Receptor β1
Ye, Liu, Li, Yi-Lin, Mellström, Karin, Mellin, Charlotta, Bladh, Lars-Göran, Koehler, Konrad, Garg, Neeraj, Garcia Collazo, Ana Maria, Litten, Chris, Husman, Bolette, Persson, Karina, Ljunggren, Jan, Grover, Gary, Sleph, Paul G, George, Rocco, Malm, Johan
Published in Journal of medicinal chemistry (24.04.2003)
Published in Journal of medicinal chemistry (24.04.2003)
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Journal Article
Thyroid receptor ligands. Part 4: 4′-amido bioisosteric ligands selective for the thyroid hormone receptor beta
Li, Yi-Lin, Litten, Chris, Koehler, Konrad F., Mellström, Karin, Garg, Neeraj, Garcia Collazo, Ana Maria, Färnegård, Mathias, Grynfarb, Marlena, Husman, Bolette, Sandberg, Johnny, Malm, Johan
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
Published in Bioorganic & medicinal chemistry letters (15.02.2006)
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Journal Article
Thyroid receptor ligands. Part 8: Thyromimetics derived from N-acylated-α-amino acid derivatives displaying modulated pharmacological selectivity compared with KB-141
Garg, Neeraj, Li, Yi-Lin, Garcia Collazo, Ana Maria, Litten, Chris, Ryono, Denis E., Zhang, Minsheng, Caringal, Yolanda, Brigance, Robert P., Meng, Wei, Washburn, William N., Agback, Peter, Mellström, Karin, Rehnmark, Stefan, Rahimi-Ghadim, Mahmoud, Norin, Thomas, Grynfarb, Marlena, Sandberg, Johnny, Grover, Gary, Malm, Johan
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
Published in Bioorganic & medicinal chemistry letters (01.08.2007)
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Journal Article
A structurally targeted allosteric regulator of GCase restores enzyme activity, reduces microgliosis, and improves fine locomotor skills in the CBE model of neuronopathic Gaucher disease
Guzman, Beatriz, Pérez, Natalia, Garcia-Collazo, Ana Maria, Cubero, Elena, Barril, Xavier, Bellotto, Manolo, Taylor, Joanne
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric [beta]-Galactosidase correctors
Rudinskiy, Mikhail, Pons-Vizcarra, Maria, Soldà, Tatiana, Fregno, Ilaria, Bergmann, Timothy Jan, Ruano, Ana, Delgado, Aida, Morales, Sara, Barril, Xavier, Bellotto, Manolo, Cubero, Elena, García-Collazo, Ana María, Pérez-Carmona, Natalia, Molinari, Maurizio
Published in PloS one (29.11.2023)
Published in PloS one (29.11.2023)
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Journal Article
Brain penetrant structurally targeted allosteric regulators for treating GLB1-related disorders
Bellotto, Manolo, Maj, Roberto, García-Collazo, Ana María, Ruano, Ana, Delgado, Aida, Morales, Sara, Cubero, Elena, Pérez-Carmona, Natalia, Barril, Xavier
Published in Molecular genetics and metabolism (01.02.2020)
Published in Molecular genetics and metabolism (01.02.2020)
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Journal Article
METHOD OF TREATING TAUOPATHIES
GARCÍA COLLAZO, Ana Maria, CALVO-FLORES GUZMAN, Beatriz, TRAPERO PUIG, Ana, CARRILLO ARREGUI, Jokin
Year of Publication 04.07.2024
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Year of Publication 04.07.2024
Patent
Heteroaryl compounds and their use
García Collazo, Ana Maria, Roberts, Richard Spurring, Cubero Jordà, Elena, Revés Vilaplana, Marc, Barril Alonso, Xavier
Year of Publication 29.08.2023
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Year of Publication 29.08.2023
Patent
COMBINATION THERAPY FOR TREATING MPS1
GARCÍA COLLAZO, Ana Maria, BARRIL ALONSO, Xavier, PEREZ CARMONA, Natalia, CUBERO JORDÀ, Elena, MAJ, Roberto
Year of Publication 04.05.2023
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Year of Publication 04.05.2023
Patent