Trimethoprim Resistance of Dihydrofolate Reductase Variants from Clinical Isolates of Pneumocystis jirovecii
QUEENER, S. F, CODY, V, PACE, J, TORKELSON, P, GANGJEE, A
Published in Antimicrobial Agents and Chemotherapy (01.10.2013)
Published in Antimicrobial Agents and Chemotherapy (01.10.2013)
Get full text
Journal Article
Synthesis, Antifolate, and Antitumor Activities of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines
Gangjee, Aleem, Vidwans, Anup, Elzein, Elfatih, McGuire, John J, Queener, Sherry F, Kisliuk, Roy L
Published in Journal of medicinal chemistry (07.06.2001)
Published in Journal of medicinal chemistry (07.06.2001)
Get full text
Journal Article
Design, Synthesis, and X-ray Crystal Structure of a Potent Dual Inhibitor of Thymidylate Synthase and Dihydrofolate Reductase as an Antitumor Agent
Gangjee, Aleem, Yu, Jianming, McGuire, John J, Cody, Vivian, Galitsky, Nikolai, Kisliuk, Roy L, Queener, Sherry F
Published in Journal of medicinal chemistry (19.10.2000)
Published in Journal of medicinal chemistry (19.10.2000)
Get full text
Journal Article
Effect of C9-Methyl Substitution and C8-C9 Conformational Restriction on Antifolate and Antitumor Activity of Classical 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines
Gangjee, Aleem, Zeng, Yibin, McGuire, John J, Kisliuk, Roy L
Published in Journal of medicinal chemistry (10.08.2000)
Published in Journal of medicinal chemistry (10.08.2000)
Get full text
Journal Article
Targeting one-carbon metabolism in syngeneic mouse model of BRCA-mutated high-grade serous ovarian cancer
Rubinsak, L.A., Wallace-Povirk, A., Hou, Z., O'Connor, C., Gangjee, A., Morris, R.T., Matherly, L.
Published in Gynecologic oncology (01.10.2020)
Published in Gynecologic oncology (01.10.2020)
Get full text
Journal Article
Design and Synthesis of Classical and Nonclassical 6-Arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as Antifolates
Gangjee, Aleem, Zeng, Yibin, Talreja, Tina, McGuire, John J, Kisliuk, Roy L, Queener, Sherry F
Published in Journal of medicinal chemistry (28.06.2007)
Published in Journal of medicinal chemistry (28.06.2007)
Get full text
Journal Article
Kinetic and Structural Analysis for Potent Antifolate Inhibition of Pneumocystis jirovecii, Pneumocystis carinii and Human Dihydrofolate Reductase (DHFR) and Their Active Site Variants
Cody, V. 1., Pace, J., Queener, S. F., Adair, O. O., Gangjee, A.
Published in Antimicrobial agents and chemotherapy (13.05.2014)
Published in Antimicrobial agents and chemotherapy (13.05.2014)
Get full text
Journal Article
Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate
Cody, V, Galitsky, N, Luft, J R, Pangborn, W, Gangjee, A, Devraj, R, Queener, S F, Blakley, R L
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.1997)
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.1997)
Get full text
Journal Article
Synthesis of Classical, Three-Carbon-Bridged 5-Substituted Furo[2,3-d]pyrimidine and 6-Substituted Pyrrolo[2,3-d]pyrimidine Analogues as Antifolates
Gangjee, Aleem, Zeng, Yibin, McGuire, John J, Mehraein, Farideh, Kisliuk, Roy L
Published in Journal of medicinal chemistry (30.12.2004)
Published in Journal of medicinal chemistry (30.12.2004)
Get full text
Journal Article
Dual Inhibitors of Thymidylate Synthase and Dihydrofolate Reductase as Antitumor Agents: Design, Synthesis, and Biological Evaluation of Classical and Nonclassical Pyrrolo[2,3-d]pyrimidine Antifolates
Gangjee, Aleem, Jain, Hiteshkumar D, Phan, Jaclyn, Lin, Xin, Song, Xiaohong, McGuire, John J, Kisliuk, Roy L
Published in Journal of medicinal chemistry (09.02.2006)
Published in Journal of medicinal chemistry (09.02.2006)
Get full text
Journal Article