Development of Novel Therapeutics Targeting the Blood–Brain Barrier: From Barrier to Carrier
Li, Jia, Zheng, Meng, Shimoni, Olga, Banks, William A., Bush, Ashley I., Gamble, Jennifer R., Shi, Bingyang
Published in Advanced science (01.08.2021)
Published in Advanced science (01.08.2021)
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Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice
Li, Jia, Zhao, Yang, Choi, Jaesung, Ting, Ka Ka, Coleman, Paul, Chen, Jinbiao, Cogger, Victoria C, Wan, Li, Shi, Zhongsong, Moller, Thorleif, Zheng, Xiangjian, Vadas, Mathew A, Gamble, Jennifer R
Published in PLoS biology (05.06.2020)
Published in PLoS biology (05.06.2020)
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Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses
Tay, Szun Szun, Wong, Yik Chun, McDonald, David M, Wood, Nicole A W, Roediger, Ben, Sierro, Frederic, Mcguffog, Claire, Alexander, Ian E, Bishop, G Alex, Gamble, Jennifer R, Weninger, Wolfgang, McCaughan, Geoffrey W, Bertolino, Patrick, Bowen, David G
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
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ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype
Liu, Renjing, Lo, Lisa, Lay, Angelina J, Zhao, Yang, Ting, Ka Ka, Robertson, Elizabeth N, Sherrah, Andrew G, Jarrah, Sorour, Li, Haibo, Zhou, Zhaoxiong, Hambly, Brett D, Richmond, David R, Jeremy, Richmond W, Bannon, Paul G, Vadas, Mathew A, Gamble, Jennifer R
Published in Circulation research (18.08.2017)
Published in Circulation research (18.08.2017)
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Novel miRNA-based drug CD5-2 reduces liver tumor growth in diethylnitrosamine-treated mice by normalizing tumor vasculature and altering immune infiltrate
Liu, Ken, Chen, Jinbiao, Zhao, Yang, Boland, Jade, Ting, Ka Ka, Lockwood, Glen, McKenzie, Catriona, Kench, James, Vadas, Mathew A., Gamble, Jennifer R., McCaughan, Geoffrey W.
Published in Frontiers in immunology (18.09.2023)
Published in Frontiers in immunology (18.09.2023)
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The Role of the MiR-181 Family in Hepatocellular Carcinoma
Chen, Jinbiao, Liu, Ken, Vadas, Mathew A, Gamble, Jennifer R, McCaughan, Geoffrey W
Published in Cells (Basel, Switzerland) (01.08.2024)
Published in Cells (Basel, Switzerland) (01.08.2024)
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The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b
Li, Jia, Zhao, Yang, Lu, Ying, Ritchie, William, Grau, Georges, Vadas, Mathew A, Gamble, Jennifer R
Published in Molecular therapy. Nucleic acids (2016)
Published in Molecular therapy. Nucleic acids (2016)
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YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment
Coleman, Paul R, Lay, Angelina J, Ting, Ka Ka, Zhao, Yang, Li, Jia, Jarrah, Sorour, Vadas, Mathew A, Gamble, Jennifer R
Published in Cell communication and signaling (03.02.2020)
Published in Cell communication and signaling (03.02.2020)
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A proinflammatory role for proteolytically cleaved annexin A1 in neutrophil transendothelial migration
Williams, Samantha L, Milne, Ian R, Bagley, Christopher J, Gamble, Jennifer R, Vadas, Mathew A, Pitson, Stuart M, Khew-Goodall, Yeesim
Published in The Journal of immunology (1950) (01.09.2010)
Published in The Journal of immunology (1950) (01.09.2010)
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Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin–restricted miRNA antagonists of miR-27
Young, Jennifer A., Ting, Ka Ka, Li, Jia, Moller, Thorleif, Dunn, Louise, Lu, Ying, Lay, Angelina J., Moses, Joshua, Prado-Lourenço, Leonel, Khachigian, Levon M., Ng, Martin, Gregory, Philip A., Goodall, Gregory J., Tsykin, Anna, Lichtenstein, Ilana, Hahn, Christopher N., Tran, Nham, Shackel, Nicholas, Kench, James G., McCaughan, Geoffrey, Vadas, Mathew A., Gamble, Jennifer R.
Published in Blood (17.10.2013)
Published in Blood (17.10.2013)
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Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice
Chen, Jinbiao, Qi, Yanfei, Zhao, Yang, Kaczorowski, Dominik, Couttas, Timothy A, Coleman, Paul R, Don, Anthony S, Bertolino, Patrick, Gamble, Jennifer R, Vadas, Mathew A, Xia, Pu, McCaughan, Geoffrey W
Published in Oncotarget (20.03.2018)
Published in Oncotarget (20.03.2018)
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Age-associated stresses induce an anti-inflammatory senescent phenotype in endothelial cells
Coleman, Paul R, Chang, Garry, Hutas, Gabor, Grimshaw, Matthew, Vadas, Mathew A, Gamble, Jennifer R
Published in Aging (Albany, NY.) (12.12.2013)
Published in Aging (Albany, NY.) (12.12.2013)
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ARHGAP18: A Flow-Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis
Lay, Angelina J, Coleman, Paul R, Formaz-Preston, Ann, Ting, Ka Ka, Roediger, Ben, Weninger, Wolfgang, Schwartz, Martin A, Vadas, Mathew A, Gamble, Jennifer R
Published in Journal of the American Heart Association (22.01.2019)
Published in Journal of the American Heart Association (22.01.2019)
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Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1–dependent activation of PI-3K/Akt and regulation of Bcl-2 family members
Limaye, Vidya, Li, Xiaochun, Hahn, Chris, Xia, Pu, Berndt, Michael C., Vadas, Mathew A., Gamble, Jennifer R.
Published in Blood (15.04.2005)
Published in Blood (15.04.2005)
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Systemic VEGF-A Neutralization Ameliorates Diet-Induced Metabolic Dysfunction
WU, Lindsay E, MEOLI, Christopher C, XIROUCHAKI, Chrysovalantou E, STEFANIE MIKOLAIZAK, A, STÖCKLI, Jacqueline, KOLUMAM, Ganesh, VAN BRUGGEN, Nicholas, GAMBLE, Jennifer R, LE COUTEUR, David G, COONEY, Gregory J, ANDRIKOPOULOS, Sofianos, JAMES, David E, MANGIAFICO, Salvatore P, FAZAKERLEY, Daniel J, COGGER, Victoria C, MOHAMAD, Mashani, PANT, Himani, KANG, Myung-Jin, POWTER, Elizabeth, BURCHFIELD, James G
Published in Diabetes (New York, N.Y.) (01.08.2014)
Published in Diabetes (New York, N.Y.) (01.08.2014)
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Angiopoietin-1 Is an Antipermeability and Anti-Inflammatory Agent In Vitro and Targets Cell Junctions
Gamble, Jennifer R, Drew, Jenny, Trezise, Libby, Underwood, Anne, Parsons, Michelle, Kasminkas, Lisa, Rudge, John, Yancopoulos, George, Vadas, Mathew A
Published in Circulation research (29.09.2000)
Published in Circulation research (29.09.2000)
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Machine learning workflows identify a microRNA signature of insulin transcription in human tissues
Wong, Wilson K.M., Joglekar, Mugdha V., Saini, Vijit, Jiang, Guozhi, Dong, Charlotte X., Chaitarvornkit, Alissa, Maciag, Grzegorz J., Gerace, Dario, Farr, Ryan J., Satoor, Sarang N., Sahu, Subhshri, Sharangdhar, Tejaswini, Ahmed, Asma S., Chew, Yi Vee, Liuwantara, David, Heng, Benjamin, Lim, Chai K., Hunter, Julie, Januszewski, Andrzej S., Sørensen, Anja E., Akil, Ammira S.A., Gamble, Jennifer R., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., O'Connell, Philip J., Guillemin, Gilles J., Martin, David, Simpson, Ann M., Hawthorne, Wayne J., Dalgaard, Louise T., Ma, Ronald C.W., Hardikar, Anandwardhan A.
Published in iScience (23.04.2021)
Published in iScience (23.04.2021)
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Effect of Disrupted SOX18 Transcription Factor Function on Tumor Growth, Vascularization, and Endothelial Development
Young, Neville, Hahn, Christopher N., Poh, Alisa, Dong, Carolyn, Wilhelm, Dagmar, Olsson, Jane, Muscat, George E. O., Parsons, Peter, Gamble, Jennifer R., Koopman, Peter
Published in JNCI : Journal of the National Cancer Institute (02.08.2006)
Published in JNCI : Journal of the National Cancer Institute (02.08.2006)
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High-density lipoproteins neutralize C-reactive protein proinflammatory activity
WADHAM, Carol, ALBANESE, Nathaniel, ROBERTS, Jane, LIJUN WANG, BAGLEY, Christopher J, GAMBLE, Jennifer R, RYE, Kerry-Anne, BARTER, Philip J, VADAS, Mathew A, PU XIA
Published in Circulation (New York, N.Y.) (04.05.2004)
Published in Circulation (New York, N.Y.) (04.05.2004)
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