Antibodies to human serum amyloid P component eliminate visceral amyloid deposits
Pepys, Mark B, Bodin, Karl, Ellmerich, Stephan, Kahan, Melvyn C, Tennent, Glenys A, Loesch, Andrzej, Gilbertson, Janet A, Hutchinson, Winston L, Mangione, Palma P, Gallimore, J. Ruth, Millar, David J, Minogue, Shane, Dhillon, Amar P, Taylor, Graham W, Bradwell, Arthur R, Petrie, Aviva, Gillmore, Julian D, Bellotti, Vittorio, Botto, Marina, Hawkins, Philip N
Published in Nature (London) (04.11.2010)
Published in Nature (London) (04.11.2010)
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Journal Article
Targeting C-reactive protein for the treatment of cardiovascular disease
Ruth Gallimore, J, Pepys, Mark B, Polara, Alessandra, Hirschfield, Gideon M, Smith, Martin D, Wood, Stephen P, Sharif, Isam, Gray, Gillian A, Sabin, Caroline A, Bellotti, Vittorio, Myers, Rebecca M, Andrew Aquilina, J, Ley, Steven V, Thompson, Darren, Hawkins, Philip N, Robinson, Carol V, Kolstoe, Simon E, Kahan, Melvyn C, Cobb, Alexander J. A, Tennent, Glenys A, Jenvey, Michelle C
Published in Nature (27.04.2006)
Published in Nature (27.04.2006)
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Journal Article
Transgenic Human C-Reactive Protein Is Not Proatherogenic in Apolipoprotein E-Deficient Mice
Hirschfield, Gideon M., Gallimore, J. Ruth, Kahan, Melvyn C., Hutchinson, Winston L., Sabin, Caroline A., Benson, G. Martin, Dhillon, Amar P., Tennent, Glenys A., Pepys, Mark B., Iversen, L. L.
Published in Proceedings of the National Academy of Sciences - PNAS (07.06.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (07.06.2005)
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Journal Article
Obesity is an important determinant of baseline serum C-reactive protein concentration in monozygotic twins, independent of genetic influences
GREENFIELD, Jerry R, SAMARAS, Katherine, JENKINS, Arthur B, KELLY, Paul J, SPECTOR, Tim D, GALLIMORE, J. Ruth, PEPYS, Mark B, CAMPBELL, Lesley V
Published in Circulation (New York, N.Y.) (22.06.2004)
Published in Circulation (New York, N.Y.) (22.06.2004)
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Journal Article
A prospective study of the sensitivity, specificity and diagnostic performance of soluble intercellular adhesion molecule 1, highly sensitive C-reactive protein, soluble E-selectin and serum amyloid A in the diagnosis of neonatal infection
Edgar, J David M, Gabriel, Vanessa, Gallimore, J Ruth, McMillan, Stanley A, Grant, Judith
Published in BMC pediatrics (16.04.2010)
Published in BMC pediatrics (16.04.2010)
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Journal Article
Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component
Kolstoe, Simon E, Ridha, Basil H, Bellotti, Vittorio, Wang, Nan, Robinson, Carol V, Crutch, Sebastian J, Keir, Geoffrey, Kukkastenvehmas, Riitta, Gallimore, J. Ruth, Hutchinson, Winston L, Hawkins, Philip N, Wood, Stephen P, Rossor, Martin N, Pepys, Mark B
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2009)
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Journal Article
The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina
Liuzzo, Giovanna, Biasucci, Luigi M, Gallimore, J. Ruth, Grillo, Rita L, Rebuzzi, Antonio G, Pepys, Mark B, Maseri, Attilio
Published in The New England journal of medicine (18.08.1994)
Published in The New England journal of medicine (18.08.1994)
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Journal Article
Role of Serum Amyloid P Component in Bacterial Infection: Protection of the Host or Protection of the Pathogen
Noursadeghi, M, Bickerstaff, M C, Gallimore, J R, Herbert, J, Cohen, J, Pepys, M B
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2000)
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Journal Article
Rapid automated high sensitivity enzyme immunoassay of C-reactive protein
WILKINS, J, GALLIMORE, J. R, MOORE, E. G, PEPYS, M. B
Published in Clinical chemistry (Baltimore, Md.) (01.06.1998)
Published in Clinical chemistry (Baltimore, Md.) (01.06.1998)
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Journal Article
Plasma protein acute-phase response in unstable angina is not induced by ischemic injury
LIUZZO, G, BIASUCCI, L. M, REBUZZI, A. G, GALLIMORE, J. R, GALIGIURI, G, LANZA, G. A, QUARANTA, G, MONACO, C, PEPYS, M. B, MASERI, A
Published in Circulation (New York, N.Y.) (15.11.1996)
Published in Circulation (New York, N.Y.) (15.11.1996)
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Journal Article
Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses
Danesh, John, Whincup, Peter, Walker, Mary, Lennon, Lucy, Thomson, Andrew, Appleby, Paul, Gallimore, J Ruth, Pepys, Mark B
Published in BMJ (22.07.2000)
Published in BMJ (22.07.2000)
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Journal Article
Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay
Sofat, Reecha, Mangione, P. Patrizia, Gallimore, J. Ruth, Hakobyan, Svetlana, Hughes, Timothy R., Shah, Tina, Goodship, Tim, D'Aiuto, Francesco, Langenberg, Claudia, Wareham, Nick, Morgan, B. Paul, Pepys, Mark B., Hingorani, Aroon D.
Published in Journal of immunological methods (30.04.2013)
Published in Journal of immunological methods (30.04.2013)
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Journal Article
Transgenic human CRP is not pro-atherogenic, pro-atherothrombotic or pro-inflammatory in apoE−/− mice
Tennent, Glenys A, Hutchinson, Winston L, Kahan, Melvyn C, Hirschfield, Gideon M, Gallimore, J. Ruth, Lewin, Jackie, Sabin, Caroline A, Dhillon, Amar P, Pepys, Mark B
Published in Atherosclerosis (01.01.2008)
Published in Atherosclerosis (01.01.2008)
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Journal Article
Isolation and characterization of pharmaceutical grade human pentraxins, serum amyloid P component and C‐reactive protein, for clinical use
Pepys, Mark B., Gallimore, J. Ruth, Lloyd, Joanne, Li, Zhanhong, Graham, David, Taylor, Graham W., Ellmerich, Stephan, Mangione, Palma P., Tennent, Glenys A., Hutchinson, Winston L., Millar, David J., Bennett, Gary, More, John, Evans, David, Mistry, Yogesh, Poole, Stephen, Hawkins, Philip N.
Published in Journal of immunological methods (31.10.2012)
Published in Journal of immunological methods (31.10.2012)
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Journal Article
Proinflammatory Effects of Bacterial Recombinant Human C-Reactive Protein Are Caused by Contamination With Bacterial Products, Not by C-Reactive Protein Itself
Pepys, Mark B, Hawkins, Philip N, Kahan, Melvyn C, Tennent, Glenys A, Gallimore, J Ruth, Graham, David, Sabin, Caroline A, Zychlinsky, Arturo, de Diego, Juana
Published in Circulation research (25.11.2005)
Published in Circulation research (25.11.2005)
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Journal Article
Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability
Clapp, Brian R, Hirschfield, Gideon M, Storry, Clare, Gallimore, J Ruth, Stidwill, Ray P, Singer, Mervyn, Deanfield, John E, MacAllister, Raymond J, Pepys, Mark B, Vallance, Patrick, Hingorani, Aroon D
Published in Circulation (New York, N.Y.) (29.03.2005)
Published in Circulation (New York, N.Y.) (29.03.2005)
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Journal Article
Serum Amyloid A, C-Reactive Protein, and Retinal Microvascular Changes in Hypertensive Diabetic and Nondiabetic Individuals: An Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy
Stettler, Christoph, Witt, Nicholas, Tapp, Robyn J, Thom, Simon, Allemann, Sabin, Tillin, Therese, Stanton, Alice, O'Brien, Eoin, Poulter, Neil, Gallimore, J. Ruth, Hughes, Alun D, Chaturvedi, Nish
Published in Diabetes care (01.06.2009)
Published in Diabetes care (01.06.2009)
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Journal Article