The combination of the NS5A and cyclophilin inhibitors results in an additive anti-HCV inhibition in humanized mice without development of resistance
Bobardt, Michael, Ramirez, Christina M, Baum, Marc M, Ure, Daren, Foster, Robert, Gallay, Philippe A
Published in PloS one (20.05.2021)
Published in PloS one (20.05.2021)
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Cyclophilin and NS5A inhibitors, but not other anti-hepatitis C virus (HCV) agents, preclude HCV-mediated formation of double-membrane-vesicle viral factories
Chatterji, Udayan, Bobardt, Michael, Tai, Andrew, Wood, Malcolm, Gallay, Philippe A
Published in Antimicrobial agents and chemotherapy (01.05.2015)
Published in Antimicrobial agents and chemotherapy (01.05.2015)
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The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice
Gallay, Philippe, Ure, Daren, Bobardt, Michael, Chatterji, Udayan, Ou, James, Trepanier, Daniel, Foster, Robert
Published in PloS one (10.06.2019)
Published in PloS one (10.06.2019)
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Cyclophilin inhibition as a strategy for the treatment of human disease
Stauffer, Winston T., Goodman, Asha Z., Gallay, Philippe A.
Published in Frontiers in pharmacology (08.07.2024)
Published in Frontiers in pharmacology (08.07.2024)
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Astodrimer sodium nasal spray forms a barrier to SARS-CoV-2 in vitro and preserves normal mucociliary function in human nasal epithelium
Paull, Jeremy R. A., Luscombe, Carolyn A., Seta, Aynaz, Heery, Graham P., Bobardt, Michael D., Gallay, Philippe A., Constant, Samuel, Castellarnau, Alex
Published in Scientific reports (11.09.2024)
Published in Scientific reports (11.09.2024)
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The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate
Bobardt, Michael, Kuo, Joseph, Chatterji, Udayan, Chanda, Sumit, Little, Susan J, Wiedemann, Norbert, Vuagniaux, Gregoire, Gallay, Philippe A
Published in PloS one (04.02.2019)
Published in PloS one (04.02.2019)
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A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents
Do, Thuc Nguyen Dan, Donckers, Kim, Vangeel, Laura, Chatterjee, Arnab K., Gallay, Philippe A., Bobardt, Michael D., Bilello, John P., Cihlar, Tomas, De Jonghe, Steven, Neyts, Johan, Jochmans, Dirk
Published in Antiviral research (01.08.2021)
Published in Antiviral research (01.08.2021)
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The Novel Cyclophilin Inhibitor CPI-431-32 Concurrently Blocks HCV and HIV-1 Infections via a Similar Mechanism of Action
Gallay, Philippe A, Bobardt, Michael D, Chatterji, Udayan, Trepanier, Daniel J, Ure, Daren, Ordonez, Cosme, Foster, Robert
Published in PloS one (11.08.2015)
Published in PloS one (11.08.2015)
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Structurally distinct cyclosporin and sanglifehrin analogs CRV431 and NV556 suppress established HCV infection in humanized-liver mice
Bobardt, Michael, Hansson, Magnus Joakim, Mayo, Patrick, Ure, Daren, Foster, Robert, Gallay, Philippe
Published in PloS one (07.08.2020)
Published in PloS one (07.08.2020)
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Prevention of vaginal and rectal HIV transmission by antiretroviral combinations in humanized mice
Gallay, Philippe A, Chatterji, Udayan, Kirchhoff, Aaron, Gandarilla, Angel, Gunawardana, Manjula, Pyles, Richard B, Marzinke, Mark A, Moss, John A, Baum, Marc M
Published in PloS one (07.09.2017)
Published in PloS one (07.09.2017)
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