KPT-8602, a second-generation inhibitor of XPO1-mediated nuclear export, is well tolerated and highly active against AML blasts and leukemia-initiating cells
Etchin, J, Berezovskaya, A, Conway, A S, Galinsky, I A, Stone, R M, Baloglu, E, Senapedis, W, Landesman, Y, Kauffman, M, Shacham, S, Wang, J C Y, Look, A T
Published in Leukemia (01.01.2017)
Published in Leukemia (01.01.2017)
Get full text
Journal Article
Long-term outcome of a pediatric-inspired regimen used for adults aged 18-50 years with newly diagnosed acute lymphoblastic leukemia
DeAngelo, D J, Stevenson, K E, Dahlberg, S E, Silverman, L B, Couban, S, Supko, J G, Amrein, P C, Ballen, K K, Seftel, M D, Turner, A R, Leber, B, Howson-Jan, K, Kelly, K, Cohen, S, Matthews, J H, Savoie, L, Wadleigh, M, Sirulnik, L A, Galinsky, I, Neuberg, D S, Sallan, S E, Stone, R M
Published in Leukemia (01.03.2015)
Published in Leukemia (01.03.2015)
Get full text
Journal Article
Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice
Etchin, J, Montero, J, Berezovskaya, A, Le, B T, Kentsis, A, Christie, A L, Conway, A S, Chen, W C, Reed, C, Mansour, M R, Ng, C E L, Adamia, S, Rodig, S J, Galinsky, I A, Stone, R M, Klebanov, B, Landesman, Y, Kauffman, M, Shacham, S, Kung, A L, Wang, J C Y, Letai, A, Look, A T
Published in Leukemia (01.01.2016)
Published in Leukemia (01.01.2016)
Get full text
Journal Article
Smac mimetics: implications for enhancement of targeted therapies in leukemia
WEISBERG, E, RAY, A, STONE, R, GALINSKY, I, FRANK, D, KUNG, A. L, GRIFFIN, J. D, BARRETT, R, NELSON, E, CHRISTIE, A. L, PORTER, D, STRAUB, C, ZAWEL, L, DALEY, J. F, LAZO-KALLANIAN, S
Published in Leukemia (01.12.2010)
Published in Leukemia (01.12.2010)
Get full text
Journal Article
Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells
Bhanot, Haymanti, Reddy, Mamatha M, Nonami, Atsushi, Weisberg, Ellen L, Bonal, Dennis, Kirschmeier, Paul T, Salgia, Sabrina, Podar, Klaus, Galinsky, Ilene, Chowdary, Tirumala K, Neuberg, Donna, Tonon, Giovanni, Stone, Richard M, Asara, John, Griffin, James D, Sattler, Martin
Published in Leukemia (01.07.2015)
Published in Leukemia (01.07.2015)
Get full text
Journal Article
Using combination therapy to override stromal-mediated chemoresistance in mutant FLT3-positive AML: synergism between FLT3 inhibitors, dasatinib/multi-targeted inhibitors and JAK inhibitors
WEISBERG, E, LIU, Q, MITSIADES, C, SMITH, R, DALEY, J. F, STONE, R, GALINSKY, I, GRIFFIN, J. D, GRAY, N, NELSON, E, KUNG, A. L, CHRISTIE, A. L, BRONSON, R, SATTLER, M, SANDA, T, ZHAO, Z, HUR, W
Published in Leukemia (01.10.2012)
Published in Leukemia (01.10.2012)
Get full text
Journal Article
Discovery of a highly potent FLT3 kinase inhibitor for FLT3-ITD-positive AML
Wu, H, Wang, A, Qi, Z, Li, X, Chen, C, Yu, K, Zou, F, Hu, C, Wang, W, Zhao, Z, Wu, J, Liu, J, Liu, X, Wang, L, Zhang, S, Stone, R M, Galinsky, I A, Griffin, J D, Weinstock, D, Christodoulou, A, Wang, H, Shen, Y, Zhai, Z, Weisberg, E L, Liu, J, Liu, Q
Published in Leukemia (01.10.2016)
Published in Leukemia (01.10.2016)
Get full text
Journal Article
Decision-making and quality of life in older adults with acute myeloid leukemia or advanced myelodysplastic syndrome
SEKERES, M. A, STONE, R. M, ZAHRIEH, D, NEUBERG, D, MORRISON, V, DE ANGELO, D. J, GALINSKY, I, LEE, S. J
Published in Leukemia (01.04.2004)
Published in Leukemia (01.04.2004)
Get full text
Journal Article
Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias
PALOMERO, T, MCKENNA, K, ASTER, J. C, LOOK, A. T, FERRANDO, A. A, O-NEIL, J, GALINSKY, I, STONE, R, SUZUKAWA, K, STIAKAKI, E, KALMANTI, M, FOX, E. A, CALIGIURI, M. A
Published in Leukemia (01.11.2006)
Published in Leukemia (01.11.2006)
Get full text
Journal Article
KIAA1509 is a novel PDGFRB fusion partner in imatinib-responsive myeloproliferative disease associated with a t(5;14)(q33;q32)
LEVINE, R. L, WADLEIGH, M, STERNBERG, D. W, WLODARSKA, I, GALINSKY, I, STONE, R. M, DEANGELO, D. J, GILLILAND, D. Gary, COOLS, J
Published in Leukemia (2005)
Published in Leukemia (2005)
Get full text
Journal Article
Smac mimetics: implications for enhancement of targeted therapies in leukemia
Weisberg, E, Ray, A, Barrett, R, Nelson, E, Christie, A L, Porter, D, Straub, C, Zawel, L, Daley, J F, Lazo-kallanian, S, Stone, R, Galinsky, I, Frank, D, Kung, A L, Griffin, J D
Published in Leukemia (01.07.2011)
Published in Leukemia (01.07.2011)
Get full text
Journal Article
P1013: OVERALL SURVIVAL IN PATIENTS WITH SYSTEMIC MASTOCYTOSIS WITH ASSOCIATED HEMATOLOGIC NEOPLASM TREATED WITH AVAPRITINIB VERSUS BEST AVAILABLE THERAPY
Reiter, A., Gotlib, J., Álvarez‐Twose, I., Radia, D. H., Luebke, J., Bobbili, P. J., Wang, A., Norregaard, C., Dimitrijević, S., Sullivan, E., Louie‐Gao, M., Schwaab, J., Galinsky, I. A., Perkins, C., Sperr, W. R., Sriskandarajah, P., Chin, A., Sendhil, S. R., Duh, M. S., Valent, P., DeAngelo, D. J.
Published in HemaSphere (23.06.2022)
Published in HemaSphere (23.06.2022)
Get full text
Journal Article
P1015: DURATION OF TREATMENT AND REDUCTION IN SERUM TRYPTASE LEVELS IN PATIENTS WITH ADVANCED SYSTEMIC MASTOCYTOSIS TREATED WITH AVAPRITINIB VERSUS BEST AVAILABLE THERAPY
Reiter, A., Gotlib, J., Álvarez‐Twose, I., Radia, D. H., Luebke, J., Bobbili, P. J., Wang, A., Norregaard, C., Dimitrijević, S., Sullivan, E., Louie‐Gao, M., Schwaab, J., Galinsky, I. A., Perkins, C., Sperr, W. R., Sriskandarajah, P., Chin, A., Sendhil, S. R., Duh, M. S., Valent, P., DeAngelo, D. J.
Published in HemaSphere (23.06.2022)
Published in HemaSphere (23.06.2022)
Get full text
Journal Article
P1014: OVERALL SURVIVAL IN PATIENTS WITH ADVANCED SYSTEMIC MASTOCYTOSIS RECEIVING AVAPRITINIB VERSUS MIDOSTAURIN OR CLADRIBINE
Reiter, A., Gotlib, J., Álvarez‐Twose, I., Radia, D. H., Luebke, J., Bobbili, P. J., Wang, A., Norregaard, C., Dimitrijević, S., Sullivan, E., Louie‐Gao, M., Schwaab, J., Galinsky, I. A., Perkins, C., Sperr, W. R., Sriskandarajah, P., Chin, A., Sendhil, S. R., Duh, M. S., Valent, P., DeAngelo, D. J.
Published in HemaSphere (23.06.2022)
Published in HemaSphere (23.06.2022)
Get full text
Journal Article
PKC 412 FLT3 inhibitor therapy in AML: results of a phase II trial
Stone, R M, De Angelo, J, Galinsky, I, Estey, E, Klimek, V, Grandin, W, Lebwohl, D, Yap, A, Cohen, P, Fox, E, Neuberg, D, Clark, J, Gilliland, D G, Griffin, J D
Published in Annals of hematology (2004)
Get full text
Published in Annals of hematology (2004)
Journal Article
A Tyrosine Kinase Created by Fusion of the PDGFRA and FIP1L1 Genes as a Therapeutic Target of Imatinib in Idiopathic Hypereosinophilic Syndrome
Cools, Jan, DeAngelo, Daniel J, Gotlib, Jason, Stover, Elizabeth H, Legare, Robert D, Cortes, Jorges, Kutok, Jeffrey, Clark, Jennifer, Galinsky, Ilene, Griffin, James D, Cross, Nicholas C.P, Tefferi, Ayalew, Malone, James, Alam, Rafeul, Schrier, Stanley L, Schmid, Janet, Rose, Michal, Vandenberghe, Peter, Verhoef, Gregor, Boogaerts, Marc, Wlodarska, Iwona, Kantarjian, Hagop, Marynen, Peter, Coutre, Steven E, Stone, Richard, Gilliland, D. Gary
Published in The New England journal of medicine (27.03.2003)
Published in The New England journal of medicine (27.03.2003)
Get full text
Journal Article
Muc1 Inhibition Reverses the Poor Immunogenicity of Leukemia Stem Cells Rendering Them Susceptible to Immunotherapy
Rosenblatt, J, Stroopinsky, D, Mills, H, Luptakova, K, Vasir, B, Joyce, R.M, Levine, J.D, Tzachanis, D, Arnason, J, Galinsky, I, Stone, R, Kufe, D, Reiter, Y, Avigan, D.E
Published in Biology of blood and marrow transplantation (2012)
Published in Biology of blood and marrow transplantation (2012)
Get full text
Journal Article
Proteomic and Genetic Approaches Identify Syk as an AML Target
Hahn, Cynthia K., Berchuck, Jacob E., Ross, Kenneth N., Kakoza, Rose M., Clauser, Karl, Schinzel, Anna C., Ross, Linda, Galinsky, Ilene, Davis, Tina N., Silver, Serena J., Root, David E., Stone, Richard M., DeAngelo, Daniel J., Carroll, Martin, Hahn, William C., Carr, Steven A., Golub, Todd R., Kung, Andrew L., Stegmaier, Kimberly
Published in Cancer cell (06.10.2009)
Published in Cancer cell (06.10.2009)
Get full text
Journal Article
Discovery of a BTK/MNK dual inhibitor for lymphoma and leukemia
Wu, H, Hu, C, Wang, A, Weisberg, E L, Chen, Y, Yun, C-H, Wang, W, Liu, Y, Liu, X, Tian, B, Wang, J, Zhao, Z, Liang, Y, Li, B, Wang, L, Wang, B, Chen, C, Buhrlage, S J, Qi, Z, Zou, F, Nonami, A, Li, Y, Fernandes, S M, Adamia, S, Stone, R M, Galinsky, I A, Wang, X, Yang, G, Griffin, J D, Brown, J R, Eck, M J, Liu, J, Gray, N S, Liu, Q
Published in Leukemia (01.01.2016)
Published in Leukemia (01.01.2016)
Get full text
Journal Article
Clinical Trial Evaluating DC/AML Fusion Cell Vaccination Alone and in Conjunction with PD-1 Blockade in AML Patients Who Achieve a Chemotherapy-Induced Remission
Rosenblatt, J, Stone, R, Avivi, I, Uhl, L, Neuberg, D, Joyce, R.M, Tzachanis, D, Levine, J.D, Boussiotis, V, Zwicker, J, Arnason, J, Luptakova, K, Steesma, D, DeAngelo, D, Galinsky, I, Vasir, B, Somaiya, P, Mills, H, Yuan, E, Bonhoff, J, Delaney, C, Drummy, N, Nicholson, L, Stroopinsky, D, Held, V, Katz, T, Rowe, J, Kufe, D, Avigan, D.E
Published in Biology of blood and marrow transplantation (2012)
Published in Biology of blood and marrow transplantation (2012)
Get full text
Journal Article