Phosphorylation of Acetyl-CoA Carboxylase by AMPK Reduces Renal Fibrosis and Is Essential for the Anti-Fibrotic Effect of Metformin
Lee, Mardiana, Katerelos, Marina, Gleich, Kurt, Galic, Sandra, Kemp, Bruce E, Mount, Peter F, Power, David A
Published in Journal of the American Society of Nephrology (01.09.2018)
Published in Journal of the American Society of Nephrology (01.09.2018)
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Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin
Fullerton, Morgan D, Galic, Sandra, Marcinko, Katarina, Sikkema, Sarah, Pulinilkunnil, Thomas, Chen, Zhi-Ping, O'Neill, Hayley M, Ford, Rebecca J, Palanivel, Rengasamy, O'Brien, Matthew, Hardie, D Grahame, Macaulay, S Lance, Schertzer, Jonathan D, Dyck, Jason R B, van Denderen, Bryce J, Kemp, Bruce E, Steinberg, Gregory R
Published in Nature medicine (01.12.2013)
Published in Nature medicine (01.12.2013)
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AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965
Dite, Toby A., Langendorf, Christopher G., Hoque, Ashfaqul, Galic, Sandra, Rebello, Richard J., Ovens, Ashley J., Lindqvist, Lisa M., Ngoei, Kevin R.W., Ling, Naomi X.Y., Furic, Luc, Kemp, Bruce E., Scott, John W., Oakhill, Jonathan S.
Published in The Journal of biological chemistry (08.06.2018)
Published in The Journal of biological chemistry (08.06.2018)
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Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease
Bayliss, Jacqueline A, Lemus, Moyra B, Stark, Romana, Santos, Vanessa V, Thompson, Aiysha, Rees, Daniel J, Galic, Sandra, Elsworth, John D, Kemp, Bruce E, Davies, Jeffrey S, Andrews, Zane B
Published in The Journal of neuroscience (09.03.2016)
Published in The Journal of neuroscience (09.03.2016)
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Journal Article
Molecular Mechanisms Underlying the Beneficial Effects of Exercise on Brain Function and Neurological Disorders
Nay, Kévin, Smiles, William J, Kaiser, Jacqueline, McAloon, Luke M, Loh, Kim, Galic, Sandra, Oakhill, Jonathan S, Gundlach, Andrew L, Scott, John W
Published in International journal of molecular sciences (14.04.2021)
Published in International journal of molecular sciences (14.04.2021)
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Journal Article
T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice
Wiede, Florian, Shields, Benjamin J., Kyparissoudis, Sock Hui Chew Konstantinos, van Vliet, Catherine, Galic, Sandra, Tremblay, Michel L., Russell, Sarah M., Godfrey, Dale I., Tiganis, Tony
Published in The Journal of clinical investigation (16.10.2023)
Published in The Journal of clinical investigation (16.10.2023)
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Journal Article
CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins
Langendorf, Christopher G., O'Brien, Matthew T., Ngoei, Kevin R.W., McAloon, Luke M., Dhagat, Urmi, Hoque, Ashfaqul, Ling, Naomi X.Y., Dite, Toby A., Galic, Sandra, Loh, Kim, Parker, Michael W., Oakhill, Jonathan S., Kemp, Bruce E., Scott, John W.
Published in The Journal of biological chemistry (27.11.2020)
Published in The Journal of biological chemistry (27.11.2020)
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The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs
Dite, Toby A, Ling, Naomi X Y, Scott, John W, Hoque, Ashfaqul, Galic, Sandra, Parker, Benjamin L, Ngoei, Kevin R W, Langendorf, Christopher G, O'Brien, Matthew T, Kundu, Mondira, Viollet, Benoit, Steinberg, Gregory R, Sakamoto, Kei, Kemp, Bruce E, Oakhill, Jonathan S
Published in Nature communications (18.09.2017)
Published in Nature communications (18.09.2017)
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The myokine meteorin‐like (metrnl) improves glucose tolerance in both skeletal muscle cells and mice by targeting AMPKα2
Lee, Jung Ok, Byun, Won Seok, Kang, Min Ju, Han, Jeong Ah, Moon, Jiyoung, Shin, Min‐Jeong, Lee, Ho Jun, Chung, Ji Hyung, Lee, Jin‐Seok, Son, Chang‐Gue, Song, Kwon‐Ho, Kim, Tae Woo, Lee, Eun‐Soo, Kim, Hong Min, Chung, Choon Hee, Ngoei, Kevin R. W., Ling, Naomi X. Y., Oakhill, Jonathan S., Galic, Sandra, Murray‐Segal, Lisa, Kemp, Bruce E., Kim, Kyoung Min, Lim, Soo, Kim, Hyeon Soo
Published in The FEBS journal (01.05.2020)
Published in The FEBS journal (01.05.2020)
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Journal Article
Deletion of Skeletal Muscle SOCS3 Prevents Insulin Resistance in Obesity
BECK JORGENSEN, Sebastian, O'NEILL, Hayley M, DER POEL, Chris Van, TROUNCE, Ian A, LYNCH, Gordon S, SCHERTZER, Jonathan D, STEINBERG, Gregory R, SYLOW, Lykke, HONEYMAN, Jane, HEWITT, Kimberly A, PALANIVEL, Rengasamy, FULLERTON, Morgan D, ÖBERG, Lisa, BALENDRAN, Anudharan, GALIC, Sandra
Published in Diabetes (New York, N.Y.) (01.01.2013)
Published in Diabetes (New York, N.Y.) (01.01.2013)
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AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice
O’Neill, Hayley M., Lally, James S., Galic, Sandra, Thomas, Melissa, Azizi, Paymon D., Fullerton, Morgan D., Smith, Brennan K., Pulinilkunnil, Thomas, Chen, Zhiping, Samaan, M. Constantine, Jorgensen, Sebastian B., Dyck, Jason R. B., Holloway, Graham P., Hawke, Thomas J., van Denderen, Bryce J., Kemp, Bruce E., Steinberg, Gregory R.
Published in Diabetologia (01.08.2014)
Published in Diabetologia (01.08.2014)
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Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance
Loh, Kim, Fukushima, Atsushi, Zhang, Xinmei, Galic, Sandra, Briggs, Dana, Enriori, Pablo J., Simonds, Stephanie, Wiede, Florian, Reichenbach, Alexander, Hauser, Christine, Sims, Natalie A., Bence, Kendra K., Zhang, Sheng, Zhang, Zhong-Yin, Kahn, Barbara B., Neel, Benjamin G., Andrews, Zane B., Cowley, Michael A., Tiganis, Tony
Published in Cell metabolism (02.11.2011)
Published in Cell metabolism (02.11.2011)
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Journal Article
Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity
Steinberg, Gregory R., O'Neill, Hayley M., Dzamko, Nicolas L., Galic, Sandra, Naim, Tim, Koopman, René, Jørgensen, Sebastian B., Honeyman, Jane, Hewitt, Kimberly, Chen, Zhi-Ping, Schertzer, Jonathan D., Scott, John W., Koentgen, Frank, Lynch, Gordon S., Watt, Matthew J., van Denderen, Bryce J.W., Campbell, Duncan J., Kemp, Bruce E.
Published in The Journal of biological chemistry (26.11.2010)
Published in The Journal of biological chemistry (26.11.2010)
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Defective AMPK regulation of cholesterol metabolism accelerates atherosclerosis by promoting HSPC mobilization and myelopoiesis
Lee, Man K.S., Cooney, Olivia D., Lin, Xuzhu, Nadarajah, Shaktypreya, Dragoljevic, Dragana, Huynh, Kevin, Onda, Danise-Ann, Galic, Sandra, Meikle, Peter J., Edlund, Thomas, Fullerton, Morgan D., Kemp, Bruce E., Murphy, Andrew J., Loh, Kim
Published in Molecular metabolism (Germany) (01.07.2022)
Published in Molecular metabolism (Germany) (01.07.2022)
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Macrophage Deletion of SOCS1 Increases Sensitivity to LPS and Palmitic Acid and Results in Systemic Inflammation and Hepatic Insulin Resistance
SACHITHANANDAN, Nirupa, GRAHAM, Kate L, GALIC, Sandra, HONEYMAN, Jane E, FYNCH, Stacey L, HEWITT, Kimberly A, STEINBERG, Gregory R, KAY, Thomas W
Published in Diabetes (New York, N.Y.) (01.08.2011)
Published in Diabetes (New York, N.Y.) (01.08.2011)
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Journal Article
Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism
Hoffman, Nolan J., Whitfield, Jamie, Janzen, Natalie R., Belhaj, Mehdi R., Galic, Sandra, Murray-Segal, Lisa, Smiles, William J., Ling, Naomi X.Y., Dite, Toby A., Scott, John W., Oakhill, Jonathan S., Brink, Robert, Kemp, Bruce E., Hawley, John A.
Published in Molecular metabolism (Germany) (01.11.2020)
Published in Molecular metabolism (Germany) (01.11.2020)
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Journal Article
AMPK β1 reduces tumor progression and improves survival in p53 null mice
Houde, Vanessa P., Donzelli, Sara, Sacconi, Andrea, Galic, Sandra, Hammill, Joanne A., Bramson, Jonathan L., Foster, Robert A., Tsakiridis, Theodoros, Kemp, Bruce E., Grasso, Giuseppe, Blandino, Giovanni, Muti, Paola, Steinberg, Gregory R.
Published in Molecular oncology (01.09.2017)
Published in Molecular oncology (01.09.2017)
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Inhibition of Adenosine Monophosphate–Activated Protein Kinase–3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance
Loh, Kim, Tam, Shanna, Murray‐Segal, Lisa, Huynh, Kevin, Meikle, Peter J., Scott, John W., van Denderen, Bryce, Chen, Zhiping, Steel, Rohan, LeBlond, Nicholas D., Burkovsky, Leah A., O’Dwyer, Conor, Nunes, Julia R.C., Steinberg, Gregory R., Fullerton, Morgan D., Galic, Sandra, Kemp, Bruce E.
Published in Hepatology communications (01.01.2019)
Published in Hepatology communications (01.01.2019)
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