Gene editing and elimination of latent herpes simplex virus in vivo
Aubert, Martine, Strongin, Daniel E., Roychoudhury, Pavitra, Loprieno, Michelle A., Haick, Anoria K., Klouser, Lindsay M., Stensland, Laurence, Huang, Meei-Li, Makhsous, Negar, Tait, Alexander, De Silva Feelixge, Harshana S., Galetto, Roman, Duchateau, Philippe, Greninger, Alexander L., Stone, Daniel, Jerome, Keith R.
Published in Nature communications (18.08.2020)
Published in Nature communications (18.08.2020)
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Journal Article
Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia
Sugita, Mayumi, Galetto, Roman, Zong, Hongliang, Ewing-Crystal, Nathan, Trujillo-Alonso, Vicenta, Mencia-Trinchant, Nuria, Yip, Winnie, Filipe, Stephanie, Lebuhotel, Celine, Gouble, Agnès, Hassane, Duane C., Smith, Julianne, Roboz, Gail J., Guzman, Monica L.
Published in Nature communications (28.04.2022)
Published in Nature communications (28.04.2022)
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Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing
Jo, Sumin, Das, Shipra, Williams, Alan, Chretien, Anne-Sophie, Pagliardini, Thomas, Le Roy, Aude, Fernandez, Jorge Postigo, Le Clerre, Diane, Jahangiri, Billal, Chion-Sotinel, Isabelle, Rozlan, Sandra, Dessez, Emilie, Gouble, Agnes, Dusséaux, Mathilde, Galetto, Roman, Duclert, Aymeric, Marcenaro, Emanuela, Devillier, Raynier, Olive, Daniel, Duchateau, Philippe, Poirot, Laurent, Valton, Julien
Published in Nature communications (30.06.2022)
Published in Nature communications (30.06.2022)
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Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells
Cai, Tianyu, Gouble, Agnès, Black, Kathryn L., Skwarska, Anna, Naqvi, Ammar S., Taylor, Deanne, Zhao, Ming, Yuan, Qi, Sugita, Mayumi, Zhang, Qi, Galetto, Roman, Filipe, Stéphanie, Cavazos, Antonio, Han, Lina, Kuruvilla, Vinitha, Ma, Helen, Weng, Connie, Liu, Chang-Gong, Liu, Xiuping, Konoplev, Sergej, Gu, Jun, Tang, Guilin, Su, Xiaoping, Al-Atrash, Gheath, Ciurea, Stefan, Neelapu, Sattva S., Lane, Andrew A., Kantarjian, Hagop, Guzman, Monica L., Pemmaraju, Naveen, Smith, Julianne, Thomas-Tikhonenko, Andrei, Konopleva, Marina
Published in Nature communications (28.04.2022)
Published in Nature communications (28.04.2022)
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Journal Article
Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy
Silva, George, Poirot, Laurent, Galetto, Roman, Smith, Julianne, Montoya, Guillermo, Duchateau, Philippe, Pâques, Frédéric
Published in Current gene therapy (01.02.2011)
Published in Current gene therapy (01.02.2011)
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Non-viral DNA delivery and TALEN editing correct the sickle cell mutation in hematopoietic stem cells
Moiani, Arianna, Letort, Gil, Lizot, Sabrina, Chalumeau, Anne, Foray, Chloe, Felix, Tristan, Le Clerre, Diane, Temburni-Blake, Sonal, Hong, Patrick, Leduc, Sophie, Pinard, Noemie, Marechal, Alan, Seclen, Eduardo, Boyne, Alex, Mayer, Louisa, Hong, Robert, Pulicani, Sylvain, Galetto, Roman, Gouble, Agnès, Cavazzana, Marina, Juillerat, Alexandre, Miccio, Annarita, Duclert, Aymeric, Duchateau, Philippe, Valton, Julien
Published in Nature communications (11.06.2024)
Published in Nature communications (11.06.2024)
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Journal Article
Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN
Dupuy, Aurélie, Valton, Julien, Leduc, Sophie, Armier, Jacques, Galetto, Roman, Gouble, Agnès, Lebuhotel, Céline, Stary, Anne, Pâques, Frédéric, Duchateau, Philippe, Sarasin, Alain, Daboussi, Fayza
Published in PloS one (13.11.2013)
Published in PloS one (13.11.2013)
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Journal Article
Meganuclease targeting HSV-1 protects against herpetic keratitis: Application to corneal transplants
Chapellier, Benoit, Guindolet, Damien, Pereira, Daniel, Galetto, Roman, Sahel, José-Alain, Labetoulle, Marc, Gabison, Eric E.
Published in Molecular therapy. Nucleic acids (13.12.2022)
Published in Molecular therapy. Nucleic acids (13.12.2022)
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Journal Article
Preclinical activity of allogeneic SLAMF7-specific CAR T-cells (UCARTCS1) in multiple myeloma
Korst, Charlotte L B M, O’Neill, Chloe, Bruins, Wassilis S C, Cosovic, Meliha, Twickler, Inoka, Verkleij, Christie P M, Le Clerre, Diane, Themeli, Maria, Chion-Sotinel, Isabelle, Zweegman, Sonja, Galetto, Roman, Mutis, Tuna, van de Donk, Niels W C J
Published in Journal for immunotherapy of cancer (25.07.2024)
Published in Journal for immunotherapy of cancer (25.07.2024)
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Journal Article
Efficient strategies for TALEN-mediated genome editing in mammalian cell lines
Valton, Julien, Cabaniols, Jean-Pierre, Galetto, Romàn, Delacote, Fabien, Duhamel, Marianne, Paris, Sebastien, Blanchard, Domique Alain, Lebuhotel, Céline, Thomas, Séverine, Moriceau, Sandra, Demirdjian, Raffy, Letort, Gil, Jacquet, Adeline, Gariboldi, Annabelle, Rolland, Sandra, Daboussi, Fayza, Juillerat, Alexandre, Bertonati, Claudia, Duclert, Aymeric, Duchateau, Philippe
Published in Methods (San Diego, Calif.) (01.09.2014)
Published in Methods (San Diego, Calif.) (01.09.2014)
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Journal Article
Targeted approaches for gene therapy and the emergence of engineered meganucleases
Galetto, Roman, Duchateau, Philippe, Pâques, Frédéric
Published in Expert opinion on biological therapy (01.10.2009)
Published in Expert opinion on biological therapy (01.10.2009)
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Journal Article
Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus
Simon-Loriere, Etienne, Galetto, Roman, Hamoudi, Meriem, Archer, John, Lefeuvre, Pierre, Martin, Darren P, Robertson, David L, Negroni, Matteo
Published in PLoS pathogens (01.05.2009)
Published in PLoS pathogens (01.05.2009)
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Journal Article
143 Mesothelin (MSLN) targeting allogeneic CAR T cells engineered to overcome tumor immunosuppressive microenvironment
Schiffer-Mannioui, Cecile, Leduc, Sophie, Chion-Sotinel, Isabelle, Clerre, Diane le, Guyot, Valérie, Rotondi, Marco, Galetto, Roman, Gouble, Agnès
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease
Aubert, Martine, Boyle, Nicole M, Stone, Daniel, Stensland, Laurence, Huang, Meei-Li, Magaret, Amalia S, Galetto, Roman, Rawlings, David J, Scharenberg, Andrew M, Jerome, Keith R
Published in Molecular therapy. Nucleic acids (01.02.2014)
Published in Molecular therapy. Nucleic acids (01.02.2014)
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Journal Article
Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies
Poirot, Laurent, Philip, Brian, Schiffer-Mannioui, Cécile, Le Clerre, Diane, Chion-Sotinel, Isabelle, Derniame, Sophie, Potrel, Pierrick, Bas, Cécile, Lemaire, Laetitia, Galetto, Roman, Lebuhotel, Céline, Eyquem, Justin, Cheung, Gordon Weng-Kit, Duclert, Aymeric, Gouble, Agnès, Arnould, Sylvain, Peggs, Karl, Pule, Martin, Scharenberg, Andrew M, Smith, Julianne
Published in Cancer research (Chicago, Ill.) (15.09.2015)
Published in Cancer research (Chicago, Ill.) (15.09.2015)
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Journal Article
Preclinical Evaluation of Allogeneic CAR T Cells Targeting BCMA for the Treatment of Multiple Myeloma
Sommer, Cesar, Boldajipour, Bijan, Kuo, Tracy C., Bentley, Trevor, Sutton, Janette, Chen, Amy, Geng, Tao, Dong, Holly, Galetto, Roman, Valton, Julien, Pertel, Thomas, Juillerat, Alexandre, Gariboldi, Annabelle, Pascua, Edward, Brown, Colleen, Chin, Sherman M., Sai, Tao, Ni, Yajin, Duchateau, Philippe, Smith, Julianne, Rajpal, Arvind, Van Blarcom, Thomas, Chaparro-Riggers, Javier, Sasu, Barbra J.
Published in Molecular therapy (05.06.2019)
Published in Molecular therapy (05.06.2019)
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Journal Article
Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma
Panowski, Siler H, Srinivasan, Surabhi, Tan, Nguyen, Tacheva-Grigorova, Silvia K, Smith, Bryan, Mak, Yvonne S L, Ning, Hongxiu, Villanueva, Jonathan, Wijewarnasuriya, Dinali, Lang, Shanshan, Melton, Zea, Ghosh, Adit, Dusseaux, Mathilde, Galetto, Roman, Heyen, Jonathan R, Sai, Tao, Van Blarcom, Thomas, Chaparro-Riggers, Javier, Sasu, Barbra J
Published in Cancer research (Chicago, Ill.) (18.07.2022)
Published in Cancer research (Chicago, Ill.) (18.07.2022)
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