Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis
Sivakumar, Pitchumani, Ammar, Ron, Thompson, John Ryan, Luo, Yi, Streltsov, Denis, Porteous, Mary, McCoubrey, Carly, Cantu, 3rd, Edward, Beers, Michael F, Jarai, Gabor, Christie, Jason D
Published in Respiratory research (24.10.2021)
Published in Respiratory research (24.10.2021)
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Journal Article
Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib
Day, Elizabeth, Waters, Beatrice, Spiegel, Katrin, Alnadaf, Tanja, Manley, Paul W., Buchdunger, Elisabeth, Walker, Christoph, Jarai, Gabor
Published in European journal of pharmacology (03.12.2008)
Published in European journal of pharmacology (03.12.2008)
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Journal Article
Notch signaling mediates TGF-β1-induced epithelial–mesenchymal transition through the induction of Snai1
Matsuno, Yosuke, Coelho, Ana Lucia, Jarai, Gabor, Westwick, John, Hogaboam, Cory M.
Published in The international journal of biochemistry & cell biology (01.05.2012)
Published in The international journal of biochemistry & cell biology (01.05.2012)
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Journal Article
Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes
Kittan, Nicolai A, Allen, Ronald M, Dhaliwal, Abhay, Cavassani, Karen A, Schaller, Matthew, Gallagher, Katherine A, Carson, 4th, William F, Mukherjee, Sumanta, Grembecka, Jolanta, Cierpicki, Tomasz, Jarai, Gabor, Westwick, John, Kunkel, Steven L, Hogaboam, Cory M
Published in PloS one (21.10.2013)
Published in PloS one (21.10.2013)
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Administration of bleomycin via the oropharyngeal aspiration route leads to sustained lung fibrosis in mice and rats as quantified by UTE-MRI and histology
Egger, Christine, Cannet, Catherine, Gérard, Christelle, Jarman, Elizabeth, Jarai, Gabor, Feige, Agnès, Suply, Thomas, Micard, Arthur, Dunbar, Andrew, Tigani, Bruno, Beckmann, Nicolau
Published in PloS one (07.05.2013)
Published in PloS one (07.05.2013)
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An inhibitor of NADPH oxidase-4 attenuates established pulmonary fibrosis in a rodent disease model
Jarman, Elizabeth R, Khambata, Valerie S, Cope, Claire, Jones, Peter, Roger, Jan, Ye, Li Yun, Duggan, Nicholas, Head, Denise, Pearce, Andrew, Press, Neil J, Bellenie, Ben, Sohal, Bindi, Jarai, Gabor
Published in American journal of respiratory cell and molecular biology (01.01.2014)
Published in American journal of respiratory cell and molecular biology (01.01.2014)
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Journal Article
SOMAscan Proteomics Identifies Serum Biomarkers Associated With Liver Fibrosis in Patients With NASH
Luo, Yi, Wadhawan, Samir, Greenfield, Alex, Decato, Benjamin E., Oseini, Abdul M., Collen, Rebecca, Shevell, Diane E., Thompson, John, Jarai, Gabor, Charles, Edgar D., Sanyal, Arun J.
Published in Hepatology communications (01.05.2021)
Published in Hepatology communications (01.05.2021)
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Journal Article
RNA sequencing of transplant-stage idiopathic pulmonary fibrosis lung reveals unique pathway regulation
Sivakumar, Pitchumani, Thompson, John Ryan, Ammar, Ron, Porteous, Mary, McCoubrey, Carly, Cantu, 3rd, Edward, Ravi, Kandasamy, Zhang, Yan, Luo, Yi, Streltsov, Denis, Beers, Michael F, Jarai, Gabor, Christie, Jason D
Published in ERJ open research (01.07.2019)
Published in ERJ open research (01.07.2019)
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Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230
Egger, Christine, Gérard, Christelle, Vidotto, Nella, Accart, Nathalie, Cannet, Catherine, Dunbar, Andrew, Tigani, Bruno, Piaia, Alessandro, Jarai, Gabor, Jarman, Elizabeth, Schmid, Herbert A, Beckmann, Nicolau
Published in American journal of physiology. Lung cellular and molecular physiology (15.06.2014)
Published in American journal of physiology. Lung cellular and molecular physiology (15.06.2014)
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Journal Article
TLR9 differentiates rapidly from slowly progressing forms of idiopathic pulmonary fibrosis
Trujillo, Glenda, Meneghin, Alessia, Flaherty, Kevin R, Sholl, Lynette M, Myers, Jeffrey L, Kazerooni, Ella A, Gross, Barry H, Oak, Sameer R, Coelho, Ana Lucia, Evanoff, Holly, Day, Elizabeth, Toews, Galen B, Joshi, Amrita D, Schaller, Matthew A, Waters, Beatrice, Jarai, Gabor, Westwick, John, Kunkel, Steven L, Martinez, Fernando J, Hogaboam, Cory M
Published in Science translational medicine (10.11.2010)
Published in Science translational medicine (10.11.2010)
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Imatinib Attenuates Hypoxia-induced Pulmonary Arterial Hypertension Pathology via Reduction in 5-Hydroxytryptamine through Inhibition of Tryptophan Hydroxylase 1 Expression
CIUCLAN, Loredana, HUSSEY, Martin J, KONSTANTINOVA, Irena, PEARCE, Andrew, ROWLANDS, David J, JARAI, Gabor, WESTWICK, John, MACLEAN, Margaret R, THOMAS, Matthew, BURTON, Victoria, GOOD, Robert, DUGGAN, Nicholas, BEACH, Sarah, JONES, Peter, FOX, Roy, CLAY, Leuan, BONNEAU, Olivier
Published in American journal of respiratory and critical care medicine (2013)
Published in American journal of respiratory and critical care medicine (2013)
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Journal Article
The anti-fibrotic effect of inhibition of TGFβ-ALK5 signalling in experimental pulmonary fibrosis in mice is attenuated in the presence of concurrent γ-herpesvirus infection
Smoktunowicz, Natalia, Alexander, Robert E, Franklin, Linda, Williams, Andrew E, Holman, Beverley, Mercer, Paul F, Jarai, Gabor, Scotton, Chris J, Chambers, Rachel C
Published in Disease models & mechanisms (01.09.2015)
Published in Disease models & mechanisms (01.09.2015)
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Journal Article
Expression of transient receptor potential C6 channels in human lung macrophages
Finney-Hayward, Tricia K, Popa, Mariana Oana, Bahra, Parmjit, Li, Su, Poll, Christopher T, Gosling, Martin, Nicholson, Andrew G, Russell, Richard E K, Kon, Onn Min, Jarai, Gabor, Westwick, John, Barnes, Peter J, Donnelly, Louise E
Published in American journal of respiratory cell and molecular biology (01.09.2010)
Published in American journal of respiratory cell and molecular biology (01.09.2010)
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Journal Article
Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases
Petrassi, Mike, Barber, Rob, Be, Celine, Beach, Sarah, Cox, Brian, D'Souza, Anne-Marie, Duggan, Nick, Hussey, Martin, Fox, Roy, Hunt, Peter, Jarai, Gabor, Kosaka, Takatoshi, Oakley, Paul, Patel, Viral, Press, Neil, Rowlands, David, Scheufler, Clemens, Schmidt, Oliver, Srinivas, Honnappa, Turner, Mary, Turner, Rob, Westwick, John, Wolfreys, Alison, Pathan, Nuzhat, Watson, Simon, Thomas, Matthew
Published in Frontiers in pharmacology (05.05.2017)
Published in Frontiers in pharmacology (05.05.2017)
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IL-10 expression profiling in human monocytes
Williams, Lynn, Jarai, Gabor, Smith, Alexandra, Finan, Peter
Published in Journal of leukocyte biology (01.10.2002)
Published in Journal of leukocyte biology (01.10.2002)
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Expression and Characterization of a 5-oxo-6E,8Z,11Z,14Z-Eicosatetraenoic Acid Receptor Highly Expressed on Human Eosinophils and Neutrophils
Jones, Carol E, Holden, Suzanne, Tenaillon, Laurent, Bhatia, Umesh, Seuwen, Klaus, Tranter, Pamela, Turner, Jonathan, Kettle, Rachel, Bouhelal, Rochdi, Charlton, Steven, Nirmala, N R, Jarai, Gabor, Finan, Peter
Published in Molecular pharmacology (01.03.2003)
Published in Molecular pharmacology (01.03.2003)
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