Chemoselective Radical Dehalogenation and C–C Bond Formation on Aryl Halide Substrates Using Organic Photoredox Catalysts
Poelma, Saemi O, Burnett, G. Leslie, Discekici, Emre H, Mattson, Kaila M, Treat, Nicolas J, Luo, Yingdong, Hudson, Zachary M, Shankel, Shelby L, Clark, Paul G, Kramer, John W, Hawker, Craig J, Read de Alaniz, Javier
Published in Journal of organic chemistry (19.08.2016)
Published in Journal of organic chemistry (19.08.2016)
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Journal Article
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal
Published in Nature chemical biology (01.10.2021)
Published in Nature chemical biology (01.10.2021)
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Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal
Published in Nature chemical biology (01.08.2021)
Published in Nature chemical biology (01.08.2021)
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Journal Article
Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth
Lee, Bianca J., Boyer, Jacob A., Burnett, G. Leslie, Thottumkara, Arun P., Tibrewal, Nidhi, Wilson, Stacy L., Hsieh, Tientien, Marquez, Abby, Lorenzana, Edward G., Evans, James W., Hulea, Laura, Kiss, Gert, Liu, Hui, Lee, Dong, Larsson, Ola, McLaughlan, Shannon, Topisirovic, Ivan, Wang, Zhengping, Wang, Zhican, Zhao, Yongyuan, Wildes, David, Aggen, James B., Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A. M., Rosen, Neal
Published in Nature chemical biology (01.11.2021)
Published in Nature chemical biology (01.11.2021)
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Journal Article
New strategies for natural products containing chroman spiroketals
Green, Jason C., Burnett, G. Leslie, Pettus, Thomas R. R.
Published in Pure and applied chemistry (01.01.2012)
Published in Pure and applied chemistry (01.01.2012)
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A Strategy for the Late-Stage Divergent Syntheses of Scyphostatin Analogues
Cha, Jacob Y, Burnett, G. Leslie, Huang, Yaodong, Davidson, Jarrod B, Pettus, Thomas R. R
Published in Journal of organic chemistry (04.03.2011)
Published in Journal of organic chemistry (04.03.2011)
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Journal Article
Controlled drug release to cancer cells from modular one-photon visible light-responsive micellar system
Poelma, Saemi O., Oh, Seung Soo, Helmy, Sameh, Knight, Abigail S., Burnett, G. Leslie, Soh, H. Tom, Hawker, Craig J., de Alaniz, Javier Read
Published in Chemical communications (Cambridge, England) (18.08.2016)
Published in Chemical communications (Cambridge, England) (18.08.2016)
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Journal Article
Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors
Burnett, G. Leslie, Yang, Yu C., Aggen, James B., Pitzen, Jennifer, Gliedt, Micah K., Semko, Chris M., Marquez, Abby, Evans, James W., Wang, Gang, Won, Walter S., Tomlinson, Aidan C. A., Kiss, Gert, Tzitzilonis, Christos, Thottumkara, Arun P., Cregg, James, Mellem, Kevin T., Choi, Jong S., Lee, Julie C., Zhao, Yongyuan, Lee, Bianca J., Meyerowitz, Justin G., Knox, John E., Jiang, Jingjing, Wang, Zhican, Wildes, David, Wang, Zhengping, Singh, Mallika, Smith, Jacqueline A. M., Gill, Adrian L.
Published in Journal of medicinal chemistry (12.01.2023)
Published in Journal of medicinal chemistry (12.01.2023)
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Journal Article
C40-, C28-, AND C-32-LINKED RAPAMYCIN ANALOGS AS MTOR INHIBITORS
JAMES JOSEPH CREGG, CHRISTOPHER MICHAEL SEMKO, ARUN P THOTTUMKARA, MICAH JAMES EVANS GLIEDT, GERT KISS, ADRIAN LIAM GILL, G LESLIE BURNETT, WALTER WON, WANG GANG, KEVIN T MELLEM, JULIE CHU-LI LEE, JENNIFER PITZEN, JAMES BRADLEY AGGEN
Year of Publication 26.12.2023
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Year of Publication 26.12.2023
Patent
RAPAMYCIN ANALOGS AS MTOR INHIBITORS
ARUN P THOTTUMKARA, NIDHI TIBREWAL, MICAH JAMES EVANS GLIEDT, WANG GANG, CHRISTOPHER SEMKO, JULIE CHU-LI LEE, GERT KISS, JENNIFER PITZEN, JAMES BRADLEY AGGEN, ADRIAN LIAM GILL, G LESLIE BURNETT, WALTER WON
Year of Publication 26.07.2023
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Year of Publication 26.07.2023
Patent
Determination of methylene bridge crosslinking in chloromethylated PS‐DVB resins
Published in Journal of polymer science. Part A, Polymer chemistry
(01.07.2016)
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Journal Article
Abstract B108: 4EBP3 mRNA as a biomarker of therapeutic response to treatment with mTORC1 inhibitors
Lee, Bianca J., Dinglasan, Nuntana, Nguyen, Tram, Lorenzana, Ed, Wilson, Stacy, Burnett, G. Leslie, Aggen, James B., Nichols, Robert J., Singh, Mallika, Wildes, David, Smith, Jaqueline A.M.
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Journal Article
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth (vol 17, pg 1065, 2021)
Lee, BJ, Boyer, JA, Burnett, GL, Thottumkara, AP, Tibrewal, N, Wilson, SL, Hsieh, T, Marquez, A, Lorenzana, EG, Evans, JW
Published in NATURE CHEMICAL BIOLOGY (01.11.2021)
Published in NATURE CHEMICAL BIOLOGY (01.11.2021)
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Publication
Abstract PR04: 4EBP1 reactivation by potent and selective bi-steric inhibitors of mTORC1
Tibrewal, Nidhi, Aggen, James B., Bassan, Abraham I., Burnett, G. Leslie, Evans, Jim, Gliedt, Micah J., Hsieh, Daphne, Kiss, Gert, Lee, Bianca J., Lee, Dong, Lorenzana, Ed, Marquez, Abby, Thottumkara, Arun, Wang, Zhengping, Wilson, Stacy, Zhao, Frances, Goldsmith, Mark, Singh, Mallika, Wildes, Pete, Gill, Adrian L., Smith, Jacqueline A.M.
Published in Molecular cancer research (01.10.2020)
Published in Molecular cancer research (01.10.2020)
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Journal Article
Controlled drug release to cancer cells from modular one-photon visible light-responsive micellar systemElectronic supplementary information (ESI) available. See DOI: 10.1039/c6cc04127b
Poelma, Saemi O, Oh, Seung Soo, Helmy, Sameh, Knight, Abigail S, Burnett, G. Leslie, Soh, H. Tom, Hawker, Craig J, Read de Alaniz, Javier
Year of Publication 18.08.2016
Year of Publication 18.08.2016
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Journal Article
Abstract ND03: Discovery of RMC-9805, an oral, covalent tri-complex KRASG12D(ON) inhibitor
Knox, John E., Burnett, G. Leslie, Weller, Caroline, Jiang, Lingyan, Zhang, Dongyu, Vita, Nicole, Marquez, Abby, Seamon, Kyle J., Gould, Andrea, Menard, Marie, Quintana, Elsa, Chen, Zhe, Wang, Zhican, Wang, Zhengping, Koltun, Elena S., Singh, Malika, Jiang, Jingjing, Wildes, David, Smith, Jacqueline A.M., Gill, Adrian L.
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Abstract LB015: Bi-steric mTORC1-selective inhibitors activate 4EBP1, suppress MYC, restore anti-tumor immunity, and cooperate with immune checkpoint inhibition to elicit tumor regression
Mahauad-Fernandez, Wadie D., Yang, Yu Chi, Lai, Ian, Park, Jangho, Yao, Lilian, Evans, James W., Atibalentja, Danielle F., Chen, Xinyu, Zhao, Zihui, Burnett, G. Leslie, Lee, Bianca J., Dinglasan, Nuntana, Shifrin, Nataliya, Ahler, Ethan, Quintana, Elsa, Gill, Adrian, Smith, Jacqueline A., Singh, Mallika, Felsher, Dean W.
Published in Cancer research (Chicago, Ill.) (14.04.2023)
Published in Cancer research (Chicago, Ill.) (14.04.2023)
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