BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo
Steegmaier, Martin, Hoffmann, Matthias, Baum, Anke, Lénárt, Péter, Petronczki, Mark, Krššák, Martin, Gürtler, Ulrich, Garin-Chesa, Pilar, Lieb, Simone, Quant, Jens, Grauert, Matthias, Adolf, Günther R., Kraut, Norbert, Peters, Jan-Michael, Rettig, Wolfgang J.
Published in Current biology (20.02.2007)
Published in Current biology (20.02.2007)
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Journal Article
Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases
Sini, Patrizia, Gürtler, Ulrich, Zahn, Stephan K, Baumann, Christoph, Rudolph, Dorothea, Baumgartinger, Rosa, Strauss, Eva, Haslinger, Christian, Tontsch-Grunt, Ulrike, Waizenegger, Irene C, Solca, Flavio, Bader, Gerd, Zoephel, Andreas, Treu, Matthias, Reiser, Ulrich, Garin-Chesa, Pilar, Boehmelt, Guido, Kraut, Norbert, Quant, Jens, Adolf, Günther R
Published in Molecular cancer therapeutics (01.10.2016)
Published in Molecular cancer therapeutics (01.10.2016)
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Journal Article
Abstract 1919: Pharmacological characterization of BI 847325, a dual inhibitor of MEK and Aurora kinases
Sini, Patrizia, Gürtler, Ulrich, Zahn, Stephan K., Boehmelt, Guido, Garin-Chesa, Pilar, Kraut, Nobert, Rudolph, Dorothea, Solca, Flavio, Tontsch-Grunt, Ulrike, Waizenegger, Irene C., Adolf, Günther R.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Abstract 1082: BI 811283, a potent inhibitor of the mitotic kinase Aurora B, shows dose- and schedule-dependent efficacy in human cancer xenograft models
Gürtler, Ulrich, Tontsch-Grunt, Ulrike, Zahn, Stephan K., Quant, Jens, Adolf, Guenther R., Solca, Flavio
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Abstract 1080: Molecular and cellular pharmacology of BI 811283, a potent inhibitor of Aurora B kinase
Tontsch-Grunt, Ulrike, Gürtler, Ulrich, Zahn, Stephan K., Boehmelt, Guido, Jarvis, Marc, Adolf, Guenther R., Solca, Flavio
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
PD2-1-1: Efficacy of BI 2536, a potent and selective inhibitor of the mitotic kinase Plk1, in models of human non-small cell lung carcinoma
Baum, Anke, Garin-Chesa, Pilar, Gürtler, Ulrich, Munzert, Gerd, Rudolph, Dorothea I.
Published in Journal of thoracic oncology (01.08.2007)
Published in Journal of thoracic oncology (01.08.2007)
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Inhibition of tumor growth in mice with severe combined immunodeficiency is mediated by heat shock protein 70 (Hsp70)-peptide–activated, CD94 positive natural killer cells
Moser, Christian, Schmidbauer, Christin, Gürtler, Ulrich, Gross, Catharina, Gehrmann, Mathias, Thonigs, Gerald, Pfister, Karin, Multhoff, Gabriele
Published in Cell stress & chaperones (01.10.2002)
Published in Cell stress & chaperones (01.10.2002)
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Construction and Validation of a Microprocessor Controlled Extracorporal Circuit in Rats for the Optimization of Isolated Limb Perfusion
Gürtler, Ulrich, Fuchs, Peter, Stangelmayer, Achim, Bernhardt, Günther, Buschauer, Armin, Spruss, Thilo
Published in Archiv der Pharmazie (Weinheim) (01.12.2004)
Published in Archiv der Pharmazie (Weinheim) (01.12.2004)
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COMPUESTOS DERIVADOS DE PIRIMIDINA COMO INHIBIDORES DE LA QUINASA AURORA
ZAHN, STEPHAN KARL, TREU, MATTHIAS, BISTER, BOJAN, BOEHMELT, GUIDO, MANTOULIDIS, ANDRES, TONTSCH-GRUNT, ULRIKE, REISER, ULRICH, SCHOOP, ANDREAS, GURTLER, ULRICH, SOLCA, FLAVIO
Year of Publication 02.02.2012
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Year of Publication 02.02.2012
Patent
2, 4 -diamino pyrimidines as cell cycle kinase inhibitors
BISTER BOJAN, TREU MATTHIAS, ZAHN STEPHAN KARL, GURTLER ULRICH, MANTOULIDIS ANDREAS, SCHOOP ANDREAS, REISER ULRICH, BOEHMELT GUIDO, SOLCA FLAVIO
Year of Publication 27.05.2009
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Year of Publication 27.05.2009
Patent
COMPUESTOS DERIVADOS DE PIRIMIDINA Y COMPOSICION FARMACEUTICA EN BASE A ELLOS
TREU, MATTHIAS, ZAHN, STEPHAN KARL, BISTER, BOJAN, BOEHMELT, GUIDO, TONTSCH-GRUNT, ULRIKE, REISER, ULRICH, MANTOULIDIS, ANDREAS, SCHOOP, ANDREAS, GURTLER, ULRICH, SOLCA, FLAVIO
Year of Publication 23.07.2008
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Year of Publication 23.07.2008
Patent
PYRIMIDINES FOR USE AS PLK INHIBITORS
GRAUERT, MATTHIAS, HAUPTMANN, RUDOLF, ENGELHARDT, HARALD, ZAHN, STEPHAN, KARL, GUERTLER, ULRICH, REISER, ULRICH, HOFFMANN, MATTHIAS, STEEGMAIER, MARTIN, STADTMUELLER, HEINZ
Year of Publication 02.11.2006
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Year of Publication 02.11.2006
Patent
PYRIMIDINES FOR USE AS PLK INHIBITORS
HAUPTMANN, RUDOLF, GRAUERT, MATTIAS, ENGELHARDT, HARALD, ZAHN, STEPHAN, KARL, GUERTLER, ULRICH, REISER, ULRICH, HOFFMANN, MATTHIAS, STEEGMAIER, MARTIN, STADTMUELLER, HEINZ
Year of Publication 01.12.2005
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Year of Publication 01.12.2005
Patent
2-Arylaminopyrimidine derivatives as PLK inhibitors
ZAHN, STEPHAN KARL, GRAUERT, MATTHIAS, HAUPTMANN, RUDOLF, ENGELHARDT, HARALD, GUERTLER, ULRICH, REISER, ULRICH, HOFFMANN, MATTHIAS, STEEGMAIER, MARTIN, STADTMUELLER, HEINZ
Year of Publication 23.11.2005
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Year of Publication 23.11.2005
Patent
2,4-DI(AMINOPHENYL) PYRIMIDINES AS PLK INHIBITORS
ZAHN, STEPHAN KARL, HAUPTMANN, RUDOLF, ENGELHARDT, HARALD, HERFURTH, LARS, BAUM, ANKE, GUERTLER, ULRICH, QUANT, JENS, REISER, ULRICH, STEEGMAIER, MARTIN, SCHOOP, ANDREAS, SOLCA, FLAVIO, STADTMUELLER, HEINZ
Year of Publication 02.03.2006
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Year of Publication 02.03.2006
Patent
2,4-DIAMINO-PYRIMIDINES USED AS AURORA INHIBITORS
KRAEMER, OLIVER, REITHER, CHARLOTTE, BOEHMELT, GUIDO, ZAHN, STEPHAN, KARL, HERFURTH, LARS, GUERTLER, ULRICH, BRUECKNER, RALPH, REISER, ULRICH, MANTOULIDIS, ANDREAS, SCHOOP, ANDREAS, TREU, MATTHIAS, ENGELHARDT, HARALD, TONTSCH-GRUNT, ULRIKE, SOLCA, FLAVIO, STADTMUELLER, HEINZ
Year of Publication 11.01.2007
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Year of Publication 11.01.2007
Patent
ALPHA-CARBOLINES AS CDK-1 INHIBITORS
BADER, GERD, JACOBI, ALBRECHT, SENNHENN, PETER, SCHNAPP, GISELA, MCCONNELL, DARRYL, HERFURTH, LARS, GUERTLER, ULRICH, HIMMELSBACH, FRANK, BRUECKNER, RALPH, PAUTSCH, ALEXANDER, REISER, ULRICH, MANTOULIDIS, ANDREAS, SCHOOP, ANDREAS, MACK, JUERGEN, TREU, MATTHIAS, BETZEMEIER, BODO, KLEIN, CHRISTIAN, TONTSCH-GRUNT, ULRIKE, WIEDENMAYER, DIETER, SPEVAK, WALTER
Year of Publication 14.12.2006
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Year of Publication 14.12.2006
Patent