Diarylquinolines Are Bactericidal for Dormant Mycobacteria as a Result of Disturbed ATP Homeostasis
Koul, Anil, Vranckx, Luc, Dendouga, Najoua, Balemans, Wendy, Van den Wyngaert, Ilse, Vergauwen, Karen, Göhlmann, Hinrich W.H., Willebrords, Rudy, Poncelet, Alain, Guillemont, Jerome, Bald, Dirk, Andries, Koen
Published in The Journal of biological chemistry (12.09.2008)
Published in The Journal of biological chemistry (12.09.2008)
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Journal Article
Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project
Verbist, Bie, Klambauer, Günter, Vervoort, Liesbet, Talloen, Willem, Shkedy, Ziv, Thas, Olivier, Bender, Andreas, Göhlmann, Hinrich W.H., Hochreiter, Sepp
Published in Drug discovery today (01.05.2015)
Published in Drug discovery today (01.05.2015)
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Journal Article
Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis
Andries, Koen, Verhasselt, Peter, Guillemont, Jerome, Göhlmann, Hinrich W. H, Neefs, Jean-Marc, Winkler, Hans, Van Gestel, Jef, Timmerman, Philip, Zhu, Min, Lee, Ennis, Williams, Peter, de Chaffoy, Didier, Huitric, Emma, Hoffner, Sven, Cambau, Emmanuelle, Truffot-Pernot, Chantal, Lounis, Nacer, Jarlier, Vincent
Published in Science (American Association for the Advancement of Science) (14.01.2005)
Published in Science (American Association for the Advancement of Science) (14.01.2005)
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Journal Article
Analysis of Affymetrix GeneChip® data using amplified RNA
Cope, Leslie, Hartman, Scott M, Göhlmann, Hinrich W.H, Tiesman, Jay P, Irizarry, Rafael A
Published in BioTechniques (01.02.2006)
Published in BioTechniques (01.02.2006)
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Journal Article
Alterations in Mucosal Immunity Identified in the Colon of Patients With Irritable Bowel Syndrome
Aerssens, Jeroen, Camilleri, Michael, Talloen, Willem, Thielemans, Leen, Göhlmann, Hinrich W.H, Van den Wyngaert, Ilse, Thielemans, Theo, De Hoogt, Ronald, Andrews, Christopher N, Bharucha, Adil E, Carlson, Paula J, Busciglio, Irene, Burton, Duane D, Smyrk, Thomas, Urrutia, Raul, Coulie, Bernard
Published in Clinical gastroenterology and hepatology (01.02.2008)
Published in Clinical gastroenterology and hepatology (01.02.2008)
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Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout
Versele, Matthias, Talloen, Willem, Rockx, Cindy, Geerts, Tamara, Janssen, Boud, Lavrijssen, Tom, King, Peter, Göhlmann, Hinrich W H, Page, Martin, Perera, Tim
Published in Molecular cancer therapeutics (01.07.2009)
Published in Molecular cancer therapeutics (01.07.2009)
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Journal Article
Translation of disease associated gene signatures across tissues
Kasim, Adetayo, Shkedy, Ziv, Lin, Dan, Van Sanden, Suzy, Abrahantes, Josè Cortiñas, Göhlmann, Hinrich W H, Bijnens, Luc, Yekutieli, Dani, Camilleri, Michael, Aerssens, Jeroen, Talloen, Willem
Published in International journal of data mining and bioinformatics (2015)
Published in International journal of data mining and bioinformatics (2015)
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Journal Article
beadarrayFilter: An R Package to Filter Beads
Forcheh, Anyiawung,Chiara, Verbeke, Geert, Kasim, Adetayo, Lin, Dan, Shkedy, Ziv, Talloen, Willem, Göhlmann, Hinrich,W.H., Clement, Lieven
Published in The R journal (2013)
Published in The R journal (2013)
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Journal Article
Testing for Trends in Dose-Response Microarray Experiments: A Comparison of Several Testing Procedures, Multiplicity and Resampling-Based Inference
Lin, Dan, Shkedy, Ziv, Yekutieli, Dani, Burzykowski, Tomasz, Göhlmann, Hinrich W.H., De Bondt, An, Perera, Tim, Geerts, Tamara, Bijnens, Luc
Published in Statistical Applications in Genetics and Molecular Biology (01.01.2007)
Published in Statistical Applications in Genetics and Molecular Biology (01.01.2007)
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Journal Article
Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism
Koul, Anil, Vranckx, Luc, Dhar, Neeraj, Göhlmann, Hinrich W H, Özdemir, Emre, Neefs, Jean-Marc, Schulz, Melanie, Lu, Ping, Mørtz, Ejvind, McKinney, John D, Andries, Koen, Bald, Dirk
Published in Nature communications (26.02.2014)
Published in Nature communications (26.02.2014)
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Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines
Cox, Michael J, Jaensch, Steffen, Van de Waeter, Jelle, Cougnaud, Laure, Seynaeve, Daan, Benalla, Soulaiman, Koo, Seong Joo, Van Den Wyngaert, Ilse, Neefs, Jean-Marc, Malkov, Dmitry, Bittremieux, Mart, Steemans, Margino, Peeters, Pieter J, Wegner, Jörg Kurt, Ceulemans, Hugo, Gustin, Emmanuel, Chong, Yolanda T, Göhlmann, Hinrich W H
Published in Scientific reports (06.08.2020)
Published in Scientific reports (06.08.2020)
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Journal Article
FABIA: factor analysis for bicluster acquisition
Hochreiter, Sepp, Bodenhofer, Ulrich, Heusel, Martin, Mayr, Andreas, Mitterecker, Andreas, Kasim, Adetayo, Khamiakova, Tatsiana, Van Sanden, Suzy, Lin, Dan, Talloen, Willem, Bijnens, Luc, Göhlmann, Hinrich W. H., Shkedy, Ziv, Clevert, Djork-Arné
Published in Bioinformatics (15.06.2010)
Published in Bioinformatics (15.06.2010)
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Journal Article
I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data
Talloen, Willem, Clevert, Djork-Arné, Hochreiter, Sepp, Amaratunga, Dhammika, Bijnens, Luc, Kass, Stefan, Göhlmann, Hinrich W.H.
Published in Bioinformatics (01.11.2007)
Published in Bioinformatics (01.11.2007)
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Journal Article
Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis
Ravindranath, Aakash Chavan, Perualila-Tan, Nolen, Kasim, Adetayo, Drakakis, Georgios, Liggi, Sonia, Brewerton, Suzanne C, Mason, Daniel, Bodkin, Michael J, Evans, David A, Bhagwat, Aditya, Talloen, Willem, Göhlmann, Hinrich W H, Shkedy, Ziv, Bender, Andreas
Published in Molecular bioSystems (01.01.2015)
Published in Molecular bioSystems (01.01.2015)
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Journal Article
Comparison of methods for the selection of genomic biomarkers
Lin, Dan, Tilahun, Abel, Abrahantes, Jose Cortinas, Shkedy, Ziv, Molenberghs, Geert, Gohlmann, Hinrich W H, Talloen, Willem, Bijnens, Luc
Published in International journal of data mining and bioinformatics (2013)
Published in International journal of data mining and bioinformatics (2013)
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Journal Article
Integrating High-Dimensional Transcriptomics and Image Analysis Tools into Early Safety Screening: Proof of Concept for a New Early Drug Development Strategy
Verbist, Bie M. P, Verheyen, Geert R, Vervoort, Liesbet, Crabbe, Marjolein, Beerens, Dominiek, Bosmans, Cindy, Jaensch, Steffen, Osselaer, Steven, Talloen, Willem, Van den Wyngaert, Ilse, Van Hecke, Geert, Wuyts, Dirk, Van Goethem, Freddy, Göhlmann, Hinrich W. H
Published in Chemical research in toxicology (19.10.2015)
Published in Chemical research in toxicology (19.10.2015)
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Journal Article
A joint modeling approach for uncovering associations between gene expression, bioactivity and chemical structure in early drug discovery to guide lead selection and genomic biomarker development
Perualila-Tan, Nolen, Kasim, Adetayo, Talloen, Willem, Verbist, Bie, Göhlmann, Hinrich W.H., QSTAR Consortium, Shkedy, Ziv
Published in Statistical applications in genetics and molecular biology (01.08.2016)
Published in Statistical applications in genetics and molecular biology (01.08.2016)
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Journal Article
Weighted similarity-based clustering of chemical structures and bioactivity data in early drug discovery
Perualila-Tan, Nolen Joy, Shkedy, Ziv, Talloen, Willem, Göhlmann, Hinrich W H, Moerbeke, Marijke Van, Kasim, Adetayo
Published in Journal of bioinformatics and computational biology (01.08.2016)
Published in Journal of bioinformatics and computational biology (01.08.2016)
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Journal Article
Abstract 115: An integrated framework of transcriptome analysis leads to mechanistic insights into the FTI/Taxol synergy
Gjyrezi, Ada, Gümüş, Zeynep H., Van den Wyngaert, Ilse, Talloen, William, Göhlmann, Hinrich W.H., Weinstein, Harel, Giannakakou, Paraskevi
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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