Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts
Guaitoli, Giambattista, Raimondi, Francesco, Gilsbach, Bernd K., Gómez-Llorente, Yacob, Deyaert, Egon, Renzi, Fabiana, Li, Xianting, Schaffner, Adam, Jagtap, Pravin Kumar Ankush, Boldt, Karsten, von Zweydorf, Felix, Gotthardt, Katja, Lorimer, Donald D., Yue, Zhenyu, Burgin, Alex, Janjic, Nebojsa, Sattler, Michael, Versées, Wim, Ueffing, Marius, Ubarretxena-Belandia, Iban, Kortholt, Arjan, Gloeckner, Christian Johannes
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2016)
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Journal Article
Gating of a G protein-sensitive Mammalian Kir3.1 Prokaryotic Kir Channel Chimera in Planar Lipid Bilayers
Leal-Pinto, Edgar, Gómez-Llorente, Yacob, Sundaram, Shobana, Tang, Qiong-Yao, Ivanova-Nikolova, Tatyana, Mahajan, Rahul, Baki, Lia, Zhang, Zhe, Chavez, Jose, Ubarretxena-Belandia, Iban, Logothetis, Diomedes E.
Published in The Journal of biological chemistry (17.12.2010)
Published in The Journal of biological chemistry (17.12.2010)
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Journal Article
Polymorphism and Double Hexamer Structure in the Archaeal Minichromosome Maintenance (MCM) Helicase from Methanobacterium thermoautotrophicum
Gómez-Llorente, Yacob, Fletcher, Ryan J., Chen, Xiaojiang S., Carazo, José M., Martín, Carmen San
Published in The Journal of biological chemistry (09.12.2005)
Published in The Journal of biological chemistry (09.12.2005)
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Journal Article
Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists
Wu, Margaret, Carballo-Jane, Ester, Zhou, Haihong, Zafian, Peter, Dai, Ge, Liu, Mindy, Lao, Julie, Kelly, Terri, Shao, Dan, Gorski, Judith, Pissarnitski, Dmitri, Kekec, Ahmet, Chen, Ying, Previs, Stephen F., Scapin, Giovanna, Gomez-Llorente, Yacob, Hollingsworth, Scott A., Yan, Lin, Feng, Danqing, Huo, Pei, Walford, Geoffrey, Erion, Mark D., Kelley, David E., Lin, Songnian, Mu, James
Published in Nature communications (17.02.2022)
Published in Nature communications (17.02.2022)
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Journal Article
The Architecture of Yeast DNA Polymerase ζ
Gómez-Llorente, Yacob, Malik, Radhika, Jain, Rinku, Choudhury, Jayati Roy, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Ubarretxena-Belandia, Iban, Aggarwal, Aneel K.
Published in Cell reports (Cambridge) (17.10.2013)
Published in Cell reports (Cambridge) (17.10.2013)
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Journal Article
Double Hexamer Disruption and Biochemical Activities of Methanobacterium thermoautotrophicum MCM
Fletcher, Ryan J., Shen, Jingping, Gómez-Llorente, Yacob, Martín, Carmen San, Carazo, José M., Chen, Xiaojiang S.
Published in The Journal of biological chemistry (23.12.2005)
Published in The Journal of biological chemistry (23.12.2005)
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Journal Article
Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin
Gomez-Llorente, Yacob, Jebara, Fady, Patra, Malay, Malik, Radhika, Nisemblat, Shahar, Chomsky-Hecht, Orna, Parnas, Avital, Azem, Abdussalam, Hirsch, Joel A., Ubarretxena-Belandia, Iban
Published in Nature communications (21.04.2020)
Published in Nature communications (21.04.2020)
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Journal Article
Author Correction: Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists
Wu, Margaret, Carballo-Jane, Ester, Zhou, Haihong, Zafian, Peter, Dai, Ge, Liu, Mindy, Lao, Julie, Kelly, Terri, Shao, Dan, Gorski, Judith, Pissarnitski, Dmitri, Kekec, Ahmet, Chen, Ying, Previs, Stephen F., Scapin, Giovanna, Gomez-Llorente, Yacob, Hollingsworth, Scott A., Yan, Lin, Feng, Danqing, Huo, Pei, Walford, Geoffrey, Erion, Mark D., Kelley, David E., Lin, Songnian, Mu, James
Published in Nature communications (23.01.2024)
Published in Nature communications (23.01.2024)
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Journal Article
Discovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants
Hollingsworth, Scott A., Noland, Cameron L., Vroom, Karin, Saha, Anasuya, Sam, Miranda, Gao, Qinshan, Zhou, Haihong, Grandy, David U., Singh, Sujata, Wen, Zhiyun, Warren, Christopher, Ma, Xiaohong Shirley, Malashock, Daniel, Galli, Jennifer, Go, Gwenny, Eddins, Michael, Mayhood, Todd, Sathiyamoorthy, Karthik, Fridman, Arthur, Raoufi, Fahimeh, Gomez-Llorente, Yacob, Patridge, Andrea, Tang, Yinyan, Chen, Shi-Juan, Bailly, Marc, Ji, Chengjie, Kingsley, Laura J., Cheng, Alan C., Geierstanger, Bernhard H., Gorman, Daniel M., Zhang, Lan, Pande, Kalyan
Published in Scientific reports (22.08.2023)
Published in Scientific reports (22.08.2023)
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Journal Article
Modeling Experimental Image Formation for Likelihood-Based Classification of Electron Microscopy Data
Scheres, Sjors H.W., Núñez-Ramírez, Rafael, Gómez-Llorente, Yacob, San Martín, Carmen, Eggermont, Paul P.B., Carazo, José María
Published in Structure (London) (01.10.2007)
Published in Structure (London) (01.10.2007)
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Journal Article
Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action
Palte, Rachel L., Juan, Veronica, Gomez-Llorente, Yacob, Bailly, Marc Andre, Chakravarthy, Kalyan, Chen, Xun, Cipriano, Daniel, Fayad, Ghassan N., Fayadat-Dilman, Laurence, Gathiaka, Symon, Greb, Heiko, Hall, Brian, Handa, Mas, Hsieh, Mark, Kofman, Esther, Lin, Heping, Miller, J. Richard, Nguyen, Nhung, O’Neil, Jennifer, Shaheen, Hussam, Sterner, Eric, Strickland, Corey, Sun, Angie, Taremi, Shane, Scapin, Giovanna
Published in Communications biology (29.07.2021)
Published in Communications biology (29.07.2021)
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Journal Article
Author Correction: Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action
Palte, Rachel L., Juan, Veronica, Gomez-Llorente, Yacob, Bailly, Marc Andre, Chakravarthy, Kalyan, Chen, Xun, Cipriano, Daniel, Fayad, Ghassan N., Fayadat-Dilman, Laurence, Gathiaka, Symon, Greb, Heiko, Hall, Brian, Handa, Mas, Hsieh, Mark, Kofman, Esther, Lin, Heping, Miller, J. Richard, Nguyen, Nhung, O’Neil, Jennifer, Shaheen, Hussam, Sterner, Eric, Strickland, Corey, Sun, Angie, Taremi, Shane, Scapin, Giovanna
Published in Communications biology (15.11.2021)
Published in Communications biology (15.11.2021)
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Journal Article
Electron Microscopy Structure of Dimeric LRRK2 Reveals a Structural and Regulatory Role of the COR Domain
Gómez Llorente, Yacob, Renzi, Fabiana, Li, Xianting, Rice, William J., Chavez, Jose, Pan, Nina, Powell, James, Yue, Zhenyu, Ubarretxena-Belandia, Iban
Published in Biophysical journal (29.01.2013)
Published in Biophysical journal (29.01.2013)
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Journal Article
Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis
Malik, Radhika, Kopylov, Mykhailo, Gomez-Llorente, Yacob, Jain, Rinku, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Ubarretxena-Belandia, Iban, Aggarwal, Aneel K.
Published in Nature structural & molecular biology (01.10.2020)
Published in Nature structural & molecular biology (01.10.2020)
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Journal Article
G protein Gating of a Kir3.1-Prokaryotic Kir Channel Chimera Functionally Reconstituted in Planar Lipid Bilayers
Leal-Pinto, Edgar, Gómez-Llorente, Yacob, Sundaram, Shobana, Tang, Qiong-Yao, Ivanova-Nikolova, Tatyana, Mahajan, Rahul, Baki, Lia, Zhang, Zhe, Chavez, Jose, Ubarretxena-Belandia, Iban, Logothetis, Diomedes E.
Published in Biophysical journal (01.02.2011)
Published in Biophysical journal (01.02.2011)
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Journal Article
Structure and mechanism of B-family DNA polymerase [zeta] specialized for translesion DNA synthesis
Malik, Radhika, Kopylov, Mykhailo, Gomez-Llorente, Yacob, Jain, Rinku, Johnson, Robert E, Prakash, Louise, Prakash, Satya
Published in Nature structural & molecular biology (01.10.2020)
Published in Nature structural & molecular biology (01.10.2020)
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Journal Article
Quantitation and characterization of serotype 6A activation for pneumococcal conjugate vaccine by cryo-EM and SEC methods
Lin, Mingxiang, Deng, James Z., Scapin, Giovanna, Yuan, Yue, Gomez-Llorente, Yacob, Tong, Weidong, Porambo, Richard, Kong, Jongrock, Ikemoto, Nori, Lancaster, Catherine, Kaelber, Jason, Winters, Michael, Zhuang, Ping
Published in Vaccine (14.11.2024)
Published in Vaccine (14.11.2024)
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Journal Article
Vitamin B 12 modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection
Schaffner, Adam, Li, Xianting, Gomez-Llorente, Yacob, Leandrou, Emmanouela, Memou, Anna, Clemente, Nicolina, Yao, Chen, Afsari, Farinaz, Zhi, Lianteng, Pan, Nina, Morohashi, Keita, Hua, Xiaoluan, Zhou, Ming-Ming, Wang, Chunyu, Zhang, Hui, Chen, Shu G, Elliott, Christopher J, Rideout, Hardy, Ubarretxena-Belandia, Iban, Yue, Zhenyu
Published in Cell research (01.04.2019)
Published in Cell research (01.04.2019)
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Journal Article
Identification, structural, and biophysical characterization of a positive modulator of human Kv3.1 channels
Chen, Yun-Ting, Hong, Mee Ra, Zhang, Xin-Jun, Kostas, James, Li, Yuxing, Kraus, Richard L, Santarelli, Vincent P, Wang, Deping, Gomez-Llorente, Yacob, Brooun, Alexei, Strickland, Corey, Soisson, Stephen M, Klein, Daniel J, Ginnetti, Anthony T, Marino, Michael J, Stachel, Shawn J, Ishchenko, Andrii
Published in Proceedings of the National Academy of Sciences - PNAS (17.10.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (17.10.2023)
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Journal Article
Cryo-EM structure of a voltage-gated potassium channel Kv3.1 in complex with a novel potentiator reveals a new binding site suggesting the mechanism of action
Chen, Yun-Ting, Heo, Mee Ra, Zhan, Xin-Jun, Kostas, James, Li, Yuxing, Kraus, Richard, Santarelli, Vincent, Gomez-Llorente, Yacob, Klein, Daniel, Ginnetti, Anthony, Marino, Michael, Stachel, Shawn, Ishchenko, Andrii
Published in Acta crystallographica. Section A, Foundations and advances (07.07.2023)
Published in Acta crystallographica. Section A, Foundations and advances (07.07.2023)
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