The Inhibitor Preincubation Effect Is Universal to SLC Transporter Assays and Is Only Partially Eliminated in the Presence of Extracellular Protein
Tátrai, Péter, Temesszentandrási-Ambrus, Csilla, Varga, Tamás, Gáborik, Zsuzsanna
Published in Drug metabolism and disposition (01.08.2023)
Published in Drug metabolism and disposition (01.08.2023)
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A Systematic In Vitro Investigation of the Inhibitor Preincubation Effect on Multiple Classes of Clinically Relevant Transporters
Tátrai, Péter, Schweigler, Patrick, Poller, Birk, Domange, Norbert, de Wilde, Roelof, Hanna, Imad, Gáborik, Zsuzsanna, Huth, Felix
Published in Drug metabolism and disposition (01.07.2019)
Published in Drug metabolism and disposition (01.07.2019)
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Journal Article
A Unique In Vitro Assay to Investigate ABCB4 Transport Function
Temesszentandrási-Ambrus, Csilla, Nagy, Gábor, Bui, Annamária, Gáborik, Zsuzsanna
Published in International journal of molecular sciences (24.02.2023)
Published in International journal of molecular sciences (24.02.2023)
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Journal Article
Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters
Bakos, Éva, Temesszentandrási-Ambrus, Csilla, Özvegy-Laczka, Csilla, Gáborik, Zsuzsanna, Sarkadi, Balázs, Telbisz, Ágnes
Published in International journal of molecular sciences (01.07.2023)
Published in International journal of molecular sciences (01.07.2023)
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Pitfalls in Predicting Hepatobiliary Drug Transport Using Human Sandwich-Cultured Hepatocytes
Kumar, Vineet, Li, Cindy Yanfei, Ishida, Kazuya, Kis, Emese, Gáborik, Zsuzsanna, Unadkat, Jashvant D.
Published in The AAPS journal (17.08.2020)
Published in The AAPS journal (17.08.2020)
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Calibrating the In Vitro-In Vivo Correlation for OATP-Mediated Drug-Drug Interactions with Rosuvastatin Using Static and PBPK Models
Sane, Rucha, Cheung, Kit Wun Kathy, Kovács, Péter, Farasyn, Taleah, Li, Ruina, Bui, Annamaria, Musib, Luna, Kis, Emese, Plise, Emile, Gáborik, Zsuzsanna
Published in Drug metabolism and disposition (01.12.2020)
Published in Drug metabolism and disposition (01.12.2020)
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Translatability of in vitro Inhibition Potency to in vivo P-Glycoprotein Mediated Drug Interaction Risk
Lazzaro, Sarah, West, Mark A., Eatemadpour, Soraya, Feng, Bo, Varma, Manthena V.S., Rodrigues, A. David, Temesszentandrási-Ambrus, Csilla, Kovács-Hajdu, Péter, Nerada, Zsuzsanna, Gáborik, Zsuzsanna, Costales, Chester
Published in Journal of pharmaceutical sciences (01.06.2023)
Published in Journal of pharmaceutical sciences (01.06.2023)
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Applicability of MDR1 Overexpressing Abcb1KO-MDCKII Cell Lines for Investigating In Vitro Species Differences and Brain Penetration Prediction
Sóskuti, Emőke, Szilvásy, Nóra, Temesszentandrási-Ambrus, Csilla, Urbán, Zoltán, Csíkvári, Olivér, Szabó, Zoltán, Kecskeméti, Gábor, Pusztai, Éva, Gáborik, Zsuzsanna
Published in Pharmaceutics (29.05.2024)
Published in Pharmaceutics (29.05.2024)
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Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC)
Kastrinou-Lampou, Vlasia, Rodríguez-Pérez, Raquel, Poller, Birk, Huth, Felix, Gáborik, Zsuzsanna, Mártonné-Tóth, Beáta, Temesszentandrási-Ambrus, Csilla, Schadt, Heiko S., Kullak-Ublick, Gerd A., Arand, Michael, Camenisch, Gian
Published in Archives of toxicology (01.10.2024)
Published in Archives of toxicology (01.10.2024)
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Membrane Transporters in Physiological Barriers of Pharmacological Importance
Nagy, Ildikó, Tóth, Beáta, Gáborik, Zsuzsanna, Erdo, Franciska, Krajcsi, Péter
Published in Current pharmaceutical design (01.01.2016)
Published in Current pharmaceutical design (01.01.2016)
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The Role of a Conserved Region of the Second Intracellular Loop in AT1 Angiotensin Receptor Activation and Signaling
Gáborik, Zsuzsanna, Jagadeesh, Gowraganahalli, Zhang, Meng, Spät, András, Catt, Kevin J, Hunyady, László
Published in Endocrinology (Philadelphia) (01.06.2003)
Published in Endocrinology (Philadelphia) (01.06.2003)
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Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor
Hunyady, Laszlo, Baukal, Albert J, Gaborik, Zsuzsanna, Olivares-Reyes, Jesus A, Bor, Marta, Szaszak, Marta, Lodge, Robert, Catt, Kevin J, Balla, Tamas
Published in The Journal of cell biology (24.06.2002)
Published in The Journal of cell biology (24.06.2002)
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P162 - Further characterization of hepatopac – non-targeted metabolite-profiling of 7 chemicals including slow clearance chemicals and metabolism-mediated toxicity
Lee, Mi-Young, Cubberley, Richard, Gáborik, Zsuzsanna, Molnár, Bálint, Herédi-Szabó, Krisztina, Kalapos-Kovács, Bernadett
Published in Drug metabolism and pharmacokinetics (2020)
Published in Drug metabolism and pharmacokinetics (2020)
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Journal Article
Complementary in vitro tools to investigate renal drug transport
Juhász, Viktória, Beéry, Erzsébet, Gáborik, Zsuzsanna, Imre, Gábor, Brown, Colin, Zolnerciks, Joseph K., Oosterhuis, Berend
Published in Drug metabolism and pharmacokinetics (01.01.2017)
Published in Drug metabolism and pharmacokinetics (01.01.2017)
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Journal Article
Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney
Li, Cindy Yanfei, Basit, Abdul, Gupta, Anshul, Gáborik, Zsuzsanna, Kis, Emese, Prasad, Bhagwat
Published in The Journal of steroid biochemistry and molecular biology (01.07.2019)
Published in The Journal of steroid biochemistry and molecular biology (01.07.2019)
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Quantitative Investigation of Irinotecan Metabolism, Transport, and Gut Microbiome Activation
Parvez, Md Masud, Basit, Abdul, Jariwala, Parth B, Gáborik, Zsuzsanna, Kis, Emese, Heyward, Scott, Redinbo, Matthew R, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.08.2021)
Published in Drug metabolism and disposition (01.08.2021)
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Successful Prediction of Human Hepatic Concentrations of Transported Drugs Using the Proteomics-Informed Relative Expression Factor Approach
Yin, Mengyue, Balhara, Ankit, Marie, Solène, Tournier, Nicolas, Gáborik, Zsuzsanna, Unadkat, Jashvant D
Published in Clinical pharmacology and therapeutics (01.03.2024)
Published in Clinical pharmacology and therapeutics (01.03.2024)
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