Discovery of Low Nanomolar and Subnanomolar Inhibitors of the Mycobacterial β-Carbonic Anhydrases Rv1284 and Rv3273
Güzel, Özlen, Maresca, Alfonso, Scozzafava, Andrea, Salman, Aydın, Balaban, Alexandru T, Supuran, Claudiu T
Published in Journal of medicinal chemistry (09.07.2009)
Published in Journal of medicinal chemistry (09.07.2009)
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New Pyridinium Salt Derivatives of 2-(Hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide as Selective Inhibitors of Tumour-Related Human Carbonic Anhydrase Isoforms IX and XII
Akdemir, Özlen- Güzel, Yazıcı, Kübra- Demir, Vullo, Daniela, Supuran, Claudiu T, Akdemir, Atilla
Published in Anti-cancer agents in medicinal chemistry (2022)
Published in Anti-cancer agents in medicinal chemistry (2022)
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Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors
Güzel-Akdemir, Özlen, Carradori, Simone, Grande, Rossella, Demir-Yazıcı, Kübra, Angeli, Andrea, Supuran, Claudiu T, Akdemir, Atilla
Published in International journal of molecular sciences (22.04.2020)
Published in International journal of molecular sciences (22.04.2020)
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Journal Article
Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII
Demir-Yazıcı, Kübra, Bua, Silvia, Akgüneş, Nurgül Mutlu, Akdemir, Atilla, Supuran, Claudiu T, Güzel-Akdemir, Özlen
Published in International journal of molecular sciences (12.05.2019)
Published in International journal of molecular sciences (12.05.2019)
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Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium Vibrio cholerae
Demir-Yazıcı, Kübra, Güzel-Akdemir, Özlen, Angeli, Andrea, Supuran, Claudiu T, Akdemir, Atilla
Published in International journal of molecular sciences (29.04.2020)
Published in International journal of molecular sciences (29.04.2020)
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Journal Article
Antiviral Properties of 5‑Sulfamoyl‑1H‑Indole-Linked Spirothiazolidinone Derivatives: A Study on Human Parainfluenza Virus-2
TRAWALLY, Muhammed, YILMAZ, Fatıma Nur, ÇELİK, Berna ÖZBEK, AKDEMİR, Atilla, AKDEMİR, Özlen GÜZEL
Published in Journal of Research in Pharmacy (2024)
Published in Journal of Research in Pharmacy (2024)
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Novel thiazolidinone-containing compounds, without the well-known sulphonamide zinc-binding group acting as human carbonic anhydrase IX inhibitors
Güzel-Akdemir, Özlen, Angeli, Andrea, Demir, Kübra, Supuran, Claudiu T., Akdemir, Atilla
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)
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Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB
Güzel, Özlen, Innocenti, Alessio, Scozzafava, Andrea, Salman, Aydın, Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry (15.07.2009)
Published in Bioorganic & medicinal chemistry (15.07.2009)
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Journal Article
Synthesis and antibacterial activity of new hybrid derivatives of 5-sulfamoyl-1H-indole and 4-thiazolidinone groups
Güzel-Akdemir, Özlen, Trawally, Muhammed, Özbek-Babuç, Mehtap, Özbek-Çelik, Berna, Ermut, Görkem, Özdemir, Hakan
Published in Monatshefte für Chemie (01.09.2020)
Published in Monatshefte für Chemie (01.09.2020)
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Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms : Kinetic and X-ray crystallographic studies
GÜZEL, Ozlen, TEMPERINI, Claudia, INNOCENTI, Alessio, SCOZZAFAVA, Andrea, SALMAN, Aydin, SUPURAN, Claudiu T
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Journal Article
Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors
Güzel, Özlen, Innocenti, Alessio, Scozzafava, Andrea, Salman, Aydın, Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry letters (15.06.2009)
Published in Bioorganic & medicinal chemistry letters (15.06.2009)
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Synthesis and biological evaluation of new 4-thiazolidinone derivatives
Güzel, Özlen, Salman, Ayd n
Published in Journal of enzyme inhibition and medicinal chemistry (01.08.2009)
Published in Journal of enzyme inhibition and medicinal chemistry (01.08.2009)
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Journal Article
Carbonic anhydrase inhibitors. The beta-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides
Güzel, Ozlen, Maresca, Alfonso, Hall, Rebecca A, Scozzafava, Andrea, Mastrolorenzo, Antonio, Mühlschlegel, Fritz A, Supuran, Claudiu T
Published in Bioorganic & medicinal chemistry letters (15.04.2010)
Published in Bioorganic & medicinal chemistry letters (15.04.2010)
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Carbonic anhydrase inhibitors : Synthesis and inhibition studies against mammalian isoforms I-XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides
GÜZEL, Ozlen, INNOCENTI, Alessio, SCOZZAFAVA, Andrea, SALMAN, Aydin, PARKKILA, Seppo, HILVO, Mika, SUPURAN, Claudiu T
Published in Bioorganic & medicinal chemistry (15.10.2008)
Published in Bioorganic & medicinal chemistry (15.10.2008)
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Journal Article
Carbonic anhydrase inhibitors. Synthesis of 2,4,6-trimethylpyridinium derivatives of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides acting as potent inhibitors of the tumor-associated isoform IX and XII
Güzel, Özlen, Maresca, Alfonso, Scozzafava, Andrea, Salman, Aydın, Balaban, Alexandru T., Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
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