Search Results - "Furtmuller, Roman" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Antiseizure Activity of Novel γ-Aminobutyric Acid (A) Receptor Subtype-Selective Benzodiazepine Analogues in Mice and Rat Models

Antiseizure Activity of Novel γ-Aminobutyric Acid (A) Receptor Subtype-Selective Benzodiazepine Analogues in Mice and Rat Models

by Rivas, Felix M, Stables, James P, Murphree, Lauren, Edwankar, Rahul V, Edwankar, Chitra R, Huang, Shengming, Jain, Hiteshkumar D, Zhou, Hao, Majumder, Samarpan, Sankar, Subramanian, Roth, Bryan L, Ramerstorfer, Joachim, Furtmüller, Roman, Sieghart, Werner, Cook, James M
Published in Journal of medicinal chemistry (09.04.2009)

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Alternate Use of Distinct Intersubunit Contacts Controls GABAA Receptor Assembly and Stoichiometry

Alternate Use of Distinct Intersubunit Contacts Controls GABAA Receptor Assembly and Stoichiometry

by Klausberger, Thomas, Sarto, Isabella, Ehya, Noosha, Fuchs, Karoline, Furtmuller, Roman, Mayer, Bernd, Huck, Sigismund, Sieghart, Werner
Published in The Journal of neuroscience (01.12.2001)

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The point mutation γ2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABAA receptor subtypes

The point mutation γ2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABAA receptor subtypes

by RAMERSTORFER, Joachim, FURTMÜLLER, Roman, VOGEL, Elisabeth, HUCK, Sigismund, SIEGHART, Werner
Published in European journal of pharmacology (01.06.2010)

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8-Substituted Triazolobenzodiazepines: In Vitro and In Vivo Pharmacology in Relation to Structural Docking at the α1 Subunit-Containing GABAA Receptor

8-Substituted Triazolobenzodiazepines: In Vitro and In Vivo Pharmacology in Relation to Structural Docking at the α1 Subunit-Containing GABAA Receptor

by Golani, Lalit K., Platt, Donna M., Rüedi-Bettschen, Daniela, Edwanker, Chitra, Huang, Shenming, Poe, Michael M., Furtmüller, Roman, Sieghart, Werner, Cook, James M., Rowlett, James K.
Published in Frontiers in pharmacology (20.04.2021)

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Selective Influence on Contextual Memory: Physiochemical Properties Associated with Selectivity of Benzodiazepine Ligands at GABAA Receptors Containing the α5 Subunit

Selective Influence on Contextual Memory: Physiochemical Properties Associated with Selectivity of Benzodiazepine Ligands at GABAA Receptors Containing the α5 Subunit

by Harris, Danni, Clayton, Terry, Cook, James, Sahbaie, Peyman, Halliwell, Robert F, Furtmüller, Roman, Huck, Sigismund, Sieghart, Werner, DeLorey, Timothy M
Published in Journal of medicinal chemistry (10.07.2008)

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Are GABAA Receptors Containing α5 Subunits Contributing to the Sedative Properties of Benzodiazepine Site Agonists?

Are GABAA Receptors Containing α5 Subunits Contributing to the Sedative Properties of Benzodiazepine Site Agonists?

by SAVIC, Miroslav M, SHENGMING HUANG, FURTMÜLLER, Roman, CLAYTON, Terry, HUCK, Sigismund, OBRADOVIC, Dragan I, UGREOIC, Nenad D, SIEGHART, Werner, BOKONJIC, Dubravko R, COOK, James M
Published in Neuropsychopharmacology (New York, N.Y.) (28.03.2007)

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The GABA A Receptor α+β− Interface: A Novel Target for Subtype Selective Drugs

The GABA A Receptor α+β− Interface: A Novel Target for Subtype Selective Drugs

by Ramerstorfer, Joachim, Furtmüller, Roman, Sarto-Jackson, Isabella, Varagic, Zdravko, Sieghart, Werner, Ernst, Margot
Published in The Journal of neuroscience (19.01.2011)

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The GABAA receptor alpha+beta- interface: a novel target for subtype selective drugs

The GABAA receptor alpha+beta- interface: a novel target for subtype selective drugs

by Ramerstorfer, Joachim, Furtmüller, Roman, Sarto-Jackson, Isabella, Varagic, Zdravko, Sieghart, Werner, Ernst, Margot
Published in The Journal of neuroscience (19.01.2011)

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A study of the structure-activity relationship of GABA sub(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis

A study of the structure-activity relationship of GABA sub(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis

by Han, Dongmei, Foersterling, FHolger, Li, Xiaoyan, Deschamps, Jeffrey R, Parrish, Damon, Cao, Hui, Rallapalli, Sundari, Clayton, Terry, Teng, Yun, Majumder, Samarpan, Sankar, Subramaniam, Roth, Bryan L, Sieghart, Werner, Furtmuller, Roman, Rowlett, James K, Weed, Michael R, Cook, James M
Published in Bioorganic & medicinal chemistry (01.10.2008)

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A study of the structure–activity relationship of GABA A–benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis

A study of the structure–activity relationship of GABA A–benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis

by Han, Dongmei, Holger Försterling, F., Li, Xiaoyan, Deschamps, Jeffrey R., Parrish, Damon, Cao, Hui, Rallapalli, Sundari, Clayton, Terry, Teng, Yun, Majumder, Samarpan, Sankar, Subramaniam, Roth, Bryan L., Sieghart, Werner, Furtmuller, Roman, Rowlett, James K., Weed, Michael R., Cook, James M.
Published in Bioorganic & medicinal chemistry (01.10.2008)

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A study of the structure-activity relationship of GABAA-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis

A study of the structure-activity relationship of GABAA-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis

by DONGMEI HAN, HOLGER FÖRSTERLING, F, SANKAR, Subramaniam, ROTH, Bryan L, SIEGHART, Werner, FURTMULLER, Roman, ROWLETT, James K, WEED, Michael R, COOK, James M, XIAOYAN LI, DESCHAMPS, Jeffrey R, PARRISH, Damon, HUI CAO, RALLAPALLI, Sundari, CLAYTON, Terry, YUN TENG, MAJUMDER, Samarpan
Published in Bioorganic & medicinal chemistry (01.10.2008)

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8-Substituted Triazolobenzodiazepines: In Vitro and In Vivo Pharmacology in Relation to Structural Docking at the α1 Subunit-Containing GABA A Receptor

8-Substituted Triazolobenzodiazepines: In Vitro and In Vivo Pharmacology in Relation to Structural Docking at the α1 Subunit-Containing GABA A Receptor

by Golani, Lalit K, Platt, Donna M, Rüedi-Bettschen, Daniela, Edwanker, Chitra, Huang, Shenming, Poe, Michael M, Furtmüller, Roman, Sieghart, Werner, Cook, James M, Rowlett, James K
Published in Frontiers in pharmacology (2021)

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Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure

Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure

by Fischer, Bradford D., Licata, Stephanie C., Edwankar, Rahul V., Wang, Zhi-Jian, Huang, Shengming, He, Xiaohui, Yu, Jianming, Zhou, Hao, Johnson, Edward M., Cook, James M., Furtmüller, Roman, Ramerstorfer, Joachim, Sieghart, Werner, Roth, Bryan L., Majumder, Samarpan, Rowlett, James K.
Published in Neuropharmacology (01.12.2010)

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PWZ-029, a compound with moderate inverse agonist functional selectivity at GABAA receptors containing α5 subunits, improves passive, but not active, avoidance learning in rats

PWZ-029, a compound with moderate inverse agonist functional selectivity at GABAA receptors containing α5 subunits, improves passive, but not active, avoidance learning in rats

by Savić, Miroslav M, Clayton, Terry, Furtmüller, Roman, Gavrilović, Ivana, Samardžić, Janko, Savić, Snežana, Huck, Sigismund, Sieghart, Werner, Cook, James M
Published in Brain research (07.05.2008)

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Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect

Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect

by Furtmüller, Roman, Schlag, Michael G, Berger, Michael, Hopf, Rudolf, Huck, Sigismund, Sieghart, Werner, Redl, Heinz
Published in The Journal of pharmacology and experimental therapeutics (01.04.2002)

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The point mutation γ2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABA A receptor subtypes

The point mutation γ2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABA A receptor subtypes

by Ramerstorfer, Joachim, Furtmüller, Roman, Vogel, Elisabeth, Huck, Sigismund, Sieghart, Werner
Published in European journal of pharmacology (2010)

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Novel positive allosteric modulators of GABAA receptors: Do subtle differences in activity at α1 plus α5 versus α2 plus α3 subunits account for dissimilarities in behavioral effects in rats?

Novel positive allosteric modulators of GABAA receptors: Do subtle differences in activity at α1 plus α5 versus α2 plus α3 subunits account for dissimilarities in behavioral effects in rats?

by Savić, Miroslav M., Majumder, Samarpan, Huang, Shengming, Edwankar, Rahul V., Furtmüller, Roman, Joksimović, Srđan, Clayton, Terry, Ramerstorfer, Joachim, Milinković, Marija M., Roth, Bryan L., Sieghart, Werner, Cook, James M.
Published in Progress in neuro-psychopharmacology & biological psychiatry (01.03.2010)

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Selective Influence on Contextual Memory: Physiochemical Properties Associated with Selectivity of Benzodiazepine Ligands at GABA A Receptors Containing the α5 Subunit

Selective Influence on Contextual Memory: Physiochemical Properties Associated with Selectivity of Benzodiazepine Ligands at GABA A Receptors Containing the α5 Subunit

by Harris, Danni, Clayton, Terry, Cook, James, Sahbaie, Peyman, Halliwell, Robert F., Furtmüller, Roman, Huck, Sigismund, Sieghart, Werner, DeLorey, Timothy M.
Published in Journal of medicinal chemistry (01.07.2008)

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Journal Article

PWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in rats

PWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in rats

by Savić, Miroslav M, Clayton, Terry, Furtmüller, Roman, Gavrilović, Ivana, Samardzić, Janko, Savić, Snezana, Huck, Sigismund, Sieghart, Werner, Cook, James M
Published in Brain research (07.05.2008)

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Alternate Use of Distinct Intersubunit Contacts Controls GABA A Receptor Assembly and Stoichiometry

Alternate Use of Distinct Intersubunit Contacts Controls GABA A Receptor Assembly and Stoichiometry

by Klausberger, Thomas, Sarto, Isabella, Ehya, Noosha, Fuchs, Karoline, Furtmüller, Roman, Mayer, Bernd, Huck, Sigismund, Sieghart, Werner
Published in The Journal of neuroscience (01.12.2001)

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Journal Article