Improving Nonspecific Binding and Solubility: Bicycloalkyl Groups and Cubanes as para‐Phenyl Bioisosteres
Auberson, Yves P., Brocklehurst, Cara, Furegati, Markus, Fessard, Thomas C., Koch, Guido, Decker, Andrea, La Vecchia, Luigi, Briard, Emmanuelle
Published in ChemMedChem (20.04.2017)
Published in ChemMedChem (20.04.2017)
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Graphitic Carbon Nitride as a Photocatalyst for Decarboxylative C(sp2)−C(sp3) Couplings via Nickel Catalysis
Lukas, Florian, Findlay, Michael T., Fillols, Méritxell, Templ, Johanna, Savino, Elia, Martin, Benjamin, Allmendinger, Simon, Furegati, Markus, Noël, Timothy
Published in Angewandte Chemie International Edition (12.08.2024)
Published in Angewandte Chemie International Edition (12.08.2024)
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Scale-Up Synthesis of IID572: A New β‑Lactamase Inhibitor
Furegati, Markus, Nocito, Sandro, Reck, Folkert, Casarez, Anthony, Simmons, Robert, Schuetz, Heiner, Koch, Guido
Published in Organic process research & development (17.07.2020)
Published in Organic process research & development (17.07.2020)
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Graphitisches Kohlenstoffnitrid als Photokatalysator für die decarboxylative C(sp2)−C(sp3) Kupplung mittels Nickelkatalyse
Lukas, Florian, Findlay, Michael T., Fillols, Méritxell, Templ, Johanna, Savino, Elia, Martin, Benjamin, Allmendinger, Simon, Furegati, Markus, Noël, Timothy
Published in Angewandte Chemie (12.08.2024)
Published in Angewandte Chemie (12.08.2024)
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Potent Nonimmunosuppressive Cyclophilin Inhibitors With Improved Pharmaceutical Properties and Decreased Transporter Inhibition
Fu, Jiping, Tjandra, Meiliana, Becker, Christopher, Bednarczyk, Dallas, Capparelli, Michael, Elling, Robert, Hanna, Imad, Fujimoto, Roger, Furegati, Markus, Karur, Subramanian, Kasprzyk, Theresa, Knapp, Mark, Leung, Kwan, Li, Xiaolin, Lu, Peichao, Mergo, Wosenu, Miault, Charlotte, Ng, Simon, Parker, David, Peng, Yunshan, Roggo, Silvio, Rivkin, Alexey, Simmons, Robert L, Wang, Michael, Wiedmann, Brigitte, Weiss, Andrew H, Xiao, Linda, Xie, Lili, Xu, Wenjian, Yifru, Aregahegn, Yang, Shengtian, Zhou, Bo, Sweeney, Zachary K
Published in Journal of medicinal chemistry (23.10.2014)
Published in Journal of medicinal chemistry (23.10.2014)
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Journal Article
IID572: A New Potentially Best-In-Class β‑Lactamase Inhibitor
Reck, Folkert, Bermingham, Alun, Blais, Johanne, Casarez, Anthony, Colvin, Richard, Dean, Charles R, Furegati, Markus, Gamboa, Luis, Growcott, Ellena, Li, Cindy, Lopez, Sara, Metzger, Louis, Nocito, Sandro, Ossola, Flavio, Phizackerley, Kaci, Rasper, Dita, Shaul, Jacob, Shen, Xiaoyu, Simmons, Robert L, Tang, Dazhi, Tashiro, Kyuto, Yue, Qin
Published in ACS infectious diseases (12.07.2019)
Published in ACS infectious diseases (12.07.2019)
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베르너 증후군 RECQ 헬리카아제(WRN)의 억제와 관련된 질환을 치료하기 위한 트리아졸로-피리미딘 유사체
ZECRI FREDERIC, FUREGATI MARKUS, BORDAS VINCENT, HOLZER PHILIPP, NOCITO SANDRO, SOTO JESSICA, BRUN JVAN, SCHOEPFER JOSEPH, HINRICHS JUERGEN HANS HERMANN, GOGNIAT GEOFFREY, YAO SHUPING, YU HUANGCHAO, PLATTNER SIMONE, STRANG ROSS, DECKER ANDREA, LIMAM FATMA, GONG WANBEN, ZHANG SISI, SCHMIEDEBERG NIKO, HAMON JACQUES, MOEBITZ HENRIK
Year of Publication 30.01.2024
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Year of Publication 30.01.2024
Patent
Discovery of Potent and Selective Antibody–Drug Conjugates with Eg5 Inhibitors through Linker and Payload Optimization
Karpov, Alexei S, Nieto-Oberhuber, Cristina M, Abrams, Tinya, Beng-Louka, Edwige, Blanco, Enrique, Chamoin, Sylvie, Chene, Patrick, Dacquignies, Isabelle, Daniel, Dylan, Dillon, Michael P, Doumampouom-Metoul, Lionel, Drosos, Nikolaos, Fedoseev, Pavel, Furegati, Markus, Granda, Brian, Grotzfeld, Robert M, Hess Clark, Suzanna, Joly, Emilie, Jones, Darryl, Lacaud-Baumlin, Marion, Lagasse-Guerro, Stephanie, Lorenzana, Edward G, Mallet, William, Martyniuk, Piotr, Marzinzik, Andreas L, Mesrouze, Yannick, Nocito, Sandro, Oei, Yoko, Perruccio, Francesca, Piizzi, Grazia, Richard, Etienne, Rudewicz, Patrick J, Schindler, Patrick, Velay, Mélanie, Venstrom, Kristine, Wang, Peiyin, Zurini, Mauro, Lafrance, Marc
Published in ACS medicinal chemistry letters (12.12.2019)
Published in ACS medicinal chemistry letters (12.12.2019)
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Journal Article
Graphitisches Kohlenstoffnitrid als Photokatalysator für die decarboxylative C(sp 2 )−C(sp 3 ) Kupplung mittels Nickelkatalyse
Lukas, Florian, Findlay, Michael T., Fillols, Méritxell, Templ, Johanna, Savino, Elia, Martin, Benjamin, Allmendinger, Simon, Furegati, Markus, Noël, Timothy
Published in Angewandte Chemie (12.08.2024)
Published in Angewandte Chemie (12.08.2024)
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베타-락타마제 억제제
FUREGATI MARKUS, LIN XIAODONG, OSSOLA FLAVIO, KOCH GUIDO, RECK FOLKERT, SIMMONS ROBERT LOWELL, ZHU QINGMING, CASAREZ ANTHONY
Year of Publication 29.05.2019
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Year of Publication 29.05.2019
Patent
7-Azaindole-3-acetic acid derivatives: Potent and selective CRTh2 receptor antagonists
Sandham, David A., Adcock, Claire, Bala, Kamlesh, Barker, Lucy, Brown, Zarin, Dubois, Gerald, Budd, David, Cox, Brian, Fairhurst, Robin A., Furegati, Markus, Leblanc, Catherine, Manini, Jodie, Profit, Rachael, Reilly, John, Stringer, Rowan, Schmidt, Alfred, Turner, Katharine L., Watson, Simon J., Willis, Jennifer, Williams, Gareth, Wilson, Caroline
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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Benzyl N ‐[(Benzyloxy)methyl]carbamate: An Improved Aminomethylation Electrophile for the Synthesis of (Benzyloxy)carbonyl (Cbz)‐Protected Chiral β 2 ‐Amino Acids
Brocklehurst, Cara E., Furegati, Markus, Müller‐Hartwieg, J. Constanze D., Ossola, Flavio, La Vecchia, Luigi
Published in Helvetica chimica acta (01.02.2010)
Published in Helvetica chimica acta (01.02.2010)
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Journal Article
Benzyl N-[(Benzyloxy)methyl]carbamate: An Improved Aminomethylation Electrophile for the Synthesis of (Benzyloxy)carbonyl (Cbz)-Protected Chiral beta(2)-Amino Acids
Brocklehurst, Cara E., Furegati, Markus, Mueller-Hartwieg, J. Constanze D., Ossola, Flavio, La Vecchia, Luigi
Published in Helvetica chimica acta (01.02.2010)
Published in Helvetica chimica acta (01.02.2010)
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Journal Article
Benzyl N-[(Benzyloxy)methyl]carbamate: An Improved Aminomethylation Electrophile for the Synthesis of (Benzyloxy)carbonyl (Cbz)-Protected Chiral β2-Amino Acids
Brocklehurst, Cara E., Furegati, Markus, Müller-Hartwieg, J. Constanze D., Ossola, Flavio, La Vecchia, Luigi
Published in Helvetica chimica acta (01.02.2010)
Published in Helvetica chimica acta (01.02.2010)
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(P,M)-1,2,3,9,10,11-Hexamethoxy-5,7-dihydrodibenz[c,e]oxepine and (P,M)-1,11-dimethyl-5,5,7,7-tetraphenyl-5,7-dihydrodibenz[c,e]oxepine
Linden, Anthony, Furegati, Markus, Rippert, Andreas J.
Published in Acta crystallographica. Section C, Crystal structure communications (01.04.2004)
Published in Acta crystallographica. Section C, Crystal structure communications (01.04.2004)
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