Enzymatic hydroxylation of an unactivated methylene C-H bond guided by molecular dynamics simulations
Narayan, Alison R H, Jiménez-Osés, Gonzalo, Liu, Peng, Negretti, Solymar, Zhao, Wanxiang, Gilbert, Michael M, Ramabhadran, Raghunath O, Yang, Yun-Fang, Furan, Lawrence R, Li, Zhe, Podust, Larissa M, Montgomery, John, Houk, K N, Sherman, David H
Published in Nature chemistry (01.08.2015)
Published in Nature chemistry (01.08.2015)
Get full text
Journal Article
Mechanism of the Intramolecular Hexadehydro-Diels–Alder Reaction
Marell, Daniel J., Furan, Lawrence R., Woods, Brian P., Lei, Xiangyun, Bendelsmith, Andrew J., Cramer, Christopher J., Hoye, Thomas R., Kuwata, Keith T.
Published in Journal of organic chemistry (04.12.2015)
Published in Journal of organic chemistry (04.12.2015)
Get full text
Journal Article
A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst
Koch, Aaron A, Hansen, Douglas A, Shende, Vikram V, Furan, Lawrence R, Houk, K. N, Jiménez-Osés, Gonzalo, Sherman, David H
Published in Journal of the American Chemical Society (27.09.2017)
Published in Journal of the American Chemical Society (27.09.2017)
Get full text
Journal Article