Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells)
Kazmi, Faraz, Hensley, Tiffini, Pope, Chad, Funk, Ryan S, Loewen, Greg J, Buckley, David B, Parkinson, Andrew
Published in Drug metabolism and disposition (01.04.2013)
Published in Drug metabolism and disposition (01.04.2013)
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Journal Article
Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro
Funk, Ryan S., Singh, Rakesh K., Becker, Mara L.
Published in Clinical and translational science (01.01.2020)
Published in Clinical and translational science (01.01.2020)
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Journal Article
Facing Real-World Challenges of Immunogenicity in Pediatric Inflammatory Bowel Disease
Gress, Kyle, Bass, Julie A, Funk, Ryan S, Morrow, Ryan P, Hasenkamp, Rachel, Shakhnovich, Valentina
Published in Frontiers in immunology (09.06.2020)
Published in Frontiers in immunology (09.06.2020)
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Journal Article
Factors associated with reduced infliximab exposure in the treatment of pediatric autoimmune disorders: a cross-sectional prospective convenience sampling study
Funk, Ryan S, Shakhnovich, Valentina, Cho, Yu Kyoung, Polireddy, Kishore, Jausurawong, Taina, Gress, Kyle, Becker, Mara L
Published in Pediatric Rheumatology (01.05.2021)
Published in Pediatric Rheumatology (01.05.2021)
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Journal Article
Plasma Metabolome Normalization in Rheumatoid Arthritis Following Initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy
Medcalf, Matthew R, Bhadbhade, Pooja, Mikuls, Ted R, O'Dell, James R, Gundry, Rebekah L, Funk, Ryan S
Published in Metabolites (30.11.2021)
Published in Metabolites (30.11.2021)
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Journal Article
Identification of Plasma Metabolomic Biomarkers of Juvenile Idiopathic Arthritis
Kumar, Amar, Tatarian, Joshua, Shakhnovich, Valentina, Chevalier, Rachel L, Sudman, Marc, Lovell, Daniel J, Thompson, Susan D, Becker, Mara L, Funk, Ryan S
Published in Metabolites (01.09.2024)
Published in Metabolites (01.09.2024)
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Journal Article
Methotrexate Disposition, Anti-Folate Activity, and Metabolomic Profiling to Identify Molecular Markers of Disease Activity and Drug Response in the Collagen-Induced Arthritis Mouse Model
Salamoun, Yezan M, Polireddy, Kishore, Cho, Yu Kyoung, Medcalf, Matthew R, Funk, Ryan S
Published in Metabolites (28.12.2021)
Published in Metabolites (28.12.2021)
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Journal Article
Low-dose methotrexate results in the selective accumulation of aminoimidazole carboxamide ribotide in an erythroblastoid cell line
Funk, Ryan S, van Haandel, Leon, Becker, Mara L, Leeder, J Steven
Published in The Journal of pharmacology and experimental therapeutics (01.10.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2013)
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Journal Article
Immunogenicity in Clinical Practice and Drug Development: When is it Significant?
Shakhnovich, Valentina, Meibohm, Bernd, Rosenberg, Amy, Kierzek, Andrzej M., Hasenkamp, Rachel, Funk, Ryan S., Thalhauser, Craig J., Graaf, Piet H., Wang, Yow‐Ming C., Hamuro, Lora
Published in Clinical and translational science (01.03.2020)
Published in Clinical and translational science (01.03.2020)
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Journal Article
Leveraging innovative technology to generate drug response phenotypes for the advancement of biomarker‐driven precision dosing
Oni‐Orisan, Akinyemi, Srinivas, Nithya, Mehta, Krina, Das, Jesmin Lohy, Nguyen, Thu T., Tison, Geoffrey H., Bauer, Scott R., Burian, Maria, Funk, Ryan S., Graham, Richard A.
Published in Clinical and translational science (01.05.2021)
Published in Clinical and translational science (01.05.2021)
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Journal Article
Mechanisms of amine accumulation in, and egress from, lysosomes
Goldman, Stephen D B, Funk, Ryan S, Rajewski, Roger A, Krise, Jeffrey P
Published in Bioanalysis (01.11.2009)
Published in Bioanalysis (01.11.2009)
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Journal Article
Plasma metabolomic profiling as a tool to identify predictive biomarkers of methotrexate efficacy in rheumatoid arthritis
Medcalf, Matthew R., Bantis, Leonidas E., Shi, Peng, Bhadbhade, Pooja, Gundry, Rebekah L., Mikuls, Ted R., England, Bryant R., O'Dell, James R., Funk, Ryan S.
Published in Seminars in arthritis and rheumatism (01.10.2022)
Published in Seminars in arthritis and rheumatism (01.10.2022)
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Journal Article
Pediatric pharmacokinetics: human development and drug disposition
Funk, Ryan S, Brown, Jacob T, Abdel-Rahman, Susan M
Published in The Pediatric clinics of North America (01.10.2012)
Published in The Pediatric clinics of North America (01.10.2012)
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Journal Article
Evaluating the impact of a flipped classroom model based on cognitive science of learning strategies in a pharmacotherapy course
Shin, Tiffany R., Burkhardt, Crystal, Kelton, Robyn, Crowl, Ashley N., Funk, Ryan S., Shrader, Sarah
Published in Currents in pharmacy teaching and learning (01.07.2022)
Published in Currents in pharmacy teaching and learning (01.07.2022)
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Journal Article