Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3
Ma, Cindy S, Chew, Gary Y J, Simpson, Nicholas, Priyadarshi, Archana, Wong, Melanie, Grimbacher, Bodo, Fulcher, David A, Tangye, Stuart G, Cook, Matthew C
Published in The Journal of experimental medicine (07.07.2008)
Published in The Journal of experimental medicine (07.07.2008)
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Journal Article
STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles
Alshekaili, Jalila, Chand, Rochna, Lee, Cindy Eunhee, Corley, Susan, Kwong, Kristy, Papa, Ilenia, Fulcher, David A., Randall, Katrina L., Leiding, Jennifer W., Ma, Cindy S., Wilkins, Marc R., Uzel, Gulbu, Goodnow, Chris C., Vinuesa, Carola G., Tangye, Stuart G., Cook, Matthew C.
Published in Scientific reports (23.02.2018)
Published in Scientific reports (23.02.2018)
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Journal Article
STAT3 is required for IL-21–induced secretion of IgE from human naive B cells
Avery, Danielle T., Ma, Cindy S., Bryant, Vanessa L., Santner-Nanan, Brigitte, Nanan, Ralph, Wong, Melanie, Fulcher, David A., Cook, Matthew C., Tangye, Stuart G.
Published in Blood (01.09.2008)
Published in Blood (01.09.2008)
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Journal Article
Non-parametric Heat Map Representation of Flow Cytometry Data: Identifying Cellular Changes Associated With Genetic Immunodeficiency Disorders
Ellyard, Julia I, Tunningley, Robert, Lorenzo, Ayla May, Jiang, Simon H, Cook, Amelia, Chand, Rochna, Talaulikar, Dipti, Hatch, Ann-Maree, Wilson, Anastasia, Vinuesa, Carola G, Cook, Matthew C, Fulcher, David A
Published in Frontiers in immunology (11.09.2019)
Published in Frontiers in immunology (11.09.2019)
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Journal Article
Autoimmunity in primary antibody deficiency is associated with protein tyrosine phosphatase nonreceptor type 22 ( PTPN22 )
Chew, Gary Y.J., MB BS, FRACP, FRCPA, Sinha, Umang, MSc, Gatenby, Paul A., MB BS, PhD, FRACP, FRCPA, DeMalmanche, Theo, MB BS, FRACP, FRCPA, Adelstein, Stephen, MB BS, PhD, FRACP, FRCPA, Garsia, Roger, MB BS, PhD, FRACP, FRCPA, Hissaria, Pravin, MB BS, MD, DM, FRCPA, FRACP, French, Martyn A., MB ChB, MD, FRACP FRCPath, FRCP, Wilson, Anastasia, BSc, MPH & TM, Whittle, Belinda, BSc, Kirkpatrick, Philippa, BSc, MBA, Riminton, D. Sean, MB BS, PhD, FRACP, FRCPA, Fulcher, David A., MB BS, PhD, FRACP, FRCPA, Cook, Matthew C., MB BS, PhD, FRACP, FRCPA
Published in Journal of allergy and clinical immunology (01.04.2013)
Published in Journal of allergy and clinical immunology (01.04.2013)
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Journal Article
Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100
Lee, Cindy Eunhee, Fulcher, David A., Whittle, Belinda, Chand, Rochna, Fewings, Nicole, Field, Matthew, Andrews, Daniel, Goodnow, Christopher C., Cook, Matthew C.
Published in Blood (06.11.2014)
Published in Blood (06.11.2014)
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Journal Article
Functional STAT3 deficiency compromises the generation of human T follicular helper cells
Ma, Cindy S., Avery, Danielle T., Chan, Anna, Batten, Marcel, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Arkwright, Peter D., Kreins, Alexandra Y., Averbuch, Diana, Engelhard, Dan, Magdorf, Klaus, Kilic, Sara S., Minegishi, Yoshiyuki, Nonoyama, Shigeaki, French, Martyn A., Choo, Sharon, Smart, Joanne M., Peake, Jane, Wong, Melanie, Gray, Paul, Cook, Matthew C., Fulcher, David A., Casanova, Jean-Laurent, Deenick, Elissa K., Tangye, Stuart G.
Published in Blood (26.04.2012)
Published in Blood (26.04.2012)
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Journal Article
Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus
Jiang, Simon H., Athanasopoulos, Vicki, Ellyard, Julia I., Chuah, Aaron, Cappello, Jean, Cook, Amelia, Prabhu, Savit B., Cardenas, Jacob, Gu, Jinghua, Stanley, Maurice, Roco, Jonathan A., Papa, Ilenia, Yabas, Mehmet, Walters, Giles D., Burgio, Gaetan, McKeon, Kathryn, Byers, James M., Burrin, Charlotte, Enders, Anselm, Miosge, Lisa A., Canete, Pablo F., Jelusic, Marija, Tasic, Velibor, Lungu, Adrian C., Alexander, Stephen I., Kitching, Arthur R., Fulcher, David A., Shen, Nan, Arsov, Todor, Gatenby, Paul A., Babon, Jeff J., Mallon, Dominic F., de Lucas Collantes, Carmen, Stone, Eric A., Wu, Philip, Field, Matthew A., Andrews, Thomas D., Cho, Eun, Pascual, Virginia, Cook, Matthew C., Vinuesa, Carola G.
Published in Nature communications (17.05.2019)
Published in Nature communications (17.05.2019)
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Journal Article
Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells
Deenick, Elissa K, Avery, Danielle T, Chan, Anna, Berglund, Lucinda J, Ives, Megan L, Moens, Leen, Stoddard, Jennifer L, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Tsumura, Miyuki, Kobayashi, Masao, Arkwright, Peter D, Averbuch, Diana, Engelhard, Dan, Roesler, Joachim, Peake, Jane, Wong, Melanie, Adelstein, Stephen, Choo, Sharon, Smart, Joanne M, French, Martyn A, Fulcher, David A, Cook, Matthew C, Picard, Capucine, Durandy, Anne, Klein, Christoph, Holland, Steven M, Uzel, Gulbu, Casanova, Jean-Laurent, Ma, Cindy S, Tangye, Stuart G
Published in The Journal of experimental medicine (18.11.2013)
Published in The Journal of experimental medicine (18.11.2013)
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Journal Article
IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells
Batten, Marcel, Ramamoorthi, Nandhini, Kljavin, Noelyn M, Ma, Cindy S, Cox, Jennifer H, Dengler, Hart S, Danilenko, Dimitry M, Caplazi, Patrick, Wong, Melanie, Fulcher, David A, Cook, Matthew C, King, Cecile, Tangye, Stuart G, de Sauvage, Frederic J, Ghilardi, Nico
Published in The Journal of experimental medicine (20.12.2010)
Published in The Journal of experimental medicine (20.12.2010)
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Journal Article
IL-21 signalling via STAT3 primes human naïve B cells to respond to IL-2 to enhance their differentiation into plasmablasts
Berglund, Lucinda J., Avery, Danielle T., Ma, Cindy S., Moens, Leen, Deenick, Elissa K., Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Wong, Melanie, Adelstein, Stephen, Arkwright, Peter D., Bacchetta, Rosa, Bezrodnik, Liliana, Dadi, Harjit, Roifman, Chaim M., Fulcher, David A., Ziegler, John B., Smart, Joanne M., Kobayashi, Masao, Picard, Capucine, Durandy, Anne, Cook, Matthew C., Casanova, Jean-Laurent, Uzel, Gulbu, Tangye, Stuart G.
Published in Blood (05.12.2013)
Published in Blood (05.12.2013)
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Journal Article
Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets
Ma, Cindy S, Wong, Natalie, Rao, Geetha, Nguyen, Akira, Avery, Danielle T, Payne, Kathryn, Torpy, James, O'Young, Patrick, Deenick, Elissa, Bustamante, Jacinta, Puel, Anne, Okada, Satoshi, Kobayashi, Masao, Martinez-Barricarte, Ruben, Elliott, Michael, Sebnem Kilic, Sara, El Baghdadi, Jamila, Minegishi, Yoshiyuki, Bousfiha, Aziz, Robertson, Nic, Hambleton, Sophie, Arkwright, Peter D, French, Martyn, Blincoe, Annaliesse K, Hsu, Peter, Campbell, Dianne E, Stormon, Michael O, Wong, Melanie, Adelstein, Stephen, Fulcher, David A, Cook, Matthew C, Stepensky, Polina, Boztug, Kaan, Beier, Rita, Ikincioğullari, Aydan, Ziegler, John B, Gray, Paul, Picard, Capucine, Boisson-Dupuis, Stéphanie, Phan, Tri Giang, Grimbacher, Bodo, Warnatz, Klaus, Holland, Steven M, Uzel, Gulbu, Casanova, Jean-Laurent, Tangye, Stuart G
Published in The Journal of experimental medicine (25.07.2016)
Published in The Journal of experimental medicine (25.07.2016)
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Journal Article
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity
Zhang, Yaoyuan, Morris, Rhiannon, Brown, Grant J, Lorenzo, Ayla May D, Meng, Xiangpeng, Kershaw, Nadia J, Kiridena, Pamudika, Burgio, Gaétan, Gross, Simon, Cappello, Jean Y, Shen, Qian, Wang, Hao, Turnbull, Cynthia, Lea-Henry, Tom, Stanley, Maurice, Yu, Zhijia, Ballard, Fiona D, Chuah, Aaron, Lee, James C, Hatch, Ann-Maree, Enders, Anselm, Masters, Seth L, Headley, Alexander P, Trnka, Peter, Mallon, Dominic, Fletcher, Jeffery T, Walters, Giles D, Šestan, Mario, Jelušić, Marija, Cook, Matthew C, Athanasopoulos, Vicki, Fulcher, David A, Babon, Jeffrey J, Vinuesa, Carola G, Ellyard, Julia I
Published in The Journal of experimental medicine (01.04.2024)
Published in The Journal of experimental medicine (01.04.2024)
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Journal Article
STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function
Wilson, Robert P, Ives, Megan L, Rao, Geetha, Lau, Anthony, Payne, Kathryn, Kobayashi, Masao, Arkwright, Peter D, Peake, Jane, Wong, Melanie, Adelstein, Stephen, Smart, Joanne M, French, Martyn A, Fulcher, David A, Picard, Capucine, Bustamante, Jacinta, Boisson-Dupuis, Stephanie, Gray, Paul, Stepensky, Polina, Warnatz, Klaus, Freeman, Alexandra F, Rossjohn, Jamie, McCluskey, James, Holland, Steven M, Casanova, Jean-Laurent, Uzel, Gulbu, Ma, Cindy S, Tangye, Stuart G, Deenick, Elissa K
Published in The Journal of experimental medicine (01.06.2015)
Published in The Journal of experimental medicine (01.06.2015)
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Journal Article
B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans
Avery, Danielle T, Deenick, Elissa K, Ma, Cindy S, Suryani, Santi, Simpson, Nicholas, Chew, Gary Y, Chan, Tyani D, Palendira, Umamainthan, Bustamante, Jacinta, Boisson-Dupuis, Stéphanie, Choo, Sharon, Bleasel, Karl E, Peake, Jane, King, Cecile, French, Martyn A, Engelhard, Dan, Al-Hajjar, Sami, Al-Muhsen, Saleh, Magdorf, Klaus, Roesler, Joachim, Arkwright, Peter D, Hissaria, Pravin, Riminton, D Sean, Wong, Melanie, Brink, Robert, Fulcher, David A, Casanova, Jean-Laurent, Cook, Matthew C, Tangye, Stuart G
Published in The Journal of experimental medicine (18.01.2010)
Published in The Journal of experimental medicine (18.01.2010)
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Journal Article
Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells
Suryani, Santi, Fulcher, David A., Santner-Nanan, Brigitte, Nanan, Ralph, Wong, Melanie, Shaw, Peter J., Gibson, John, Williams, Andrew, Tangye, Stuart G.
Published in Blood (21.01.2010)
Published in Blood (21.01.2010)
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