The oral hypoxia-inducible factor prolyl hydroxylase inhibitor enarodustat counteracts alterations in renal energy metabolism in the early stages of diabetic kidney disease
Hasegawa, Sho, Tanaka, Tetsuhiro, Saito, Tomoyuki, Fukui, Kenji, Wakashima, Takeshi, Susaki, Etsuo A., Ueda, Hiroki R., Nangaku, Masaomi
Published in Kidney international (01.05.2020)
Published in Kidney international (01.05.2020)
Get full text
Journal Article
Effects of a prolyl hydroxylase inhibitor on kidney and cardiovascular complications in a rat model of chronic kidney disease
Uchida, Lisa, Tanaka, Tetsuhiro, Saito, Hisako, Sugahara, Mai, Wakashima, Takeshi, Fukui, Kenji, Nangaku, Masaomi
Published in American journal of physiology. Renal physiology (01.02.2020)
Published in American journal of physiology. Renal physiology (01.02.2020)
Get full text
Journal Article
Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice
Sugahara, Mai, Tanaka, Shinji, Tanaka, Tetsuhiro, Saito, Hisako, Ishimoto, Yu, Wakashima, Takeshi, Ueda, Masatoshi, Fukui, Kenji, Shimizu, Akira, Inagi, Reiko, Yamauchi, Toshimasa, Kadowaki, Takashi, Nangaku, Masaomi
Published in Journal of the American Society of Nephrology (01.03.2020)
Published in Journal of the American Society of Nephrology (01.03.2020)
Get full text
Journal Article
Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet
Saito, Hisako, Tanaka, Tetsuhiro, Sugahara, Mai, Tanaka, Shinji, Fukui, Kenji, Wakashima, Takeshi, Nangaku, Masaomi
Published in Laboratory investigation (01.08.2019)
Published in Laboratory investigation (01.08.2019)
Get full text
Journal Article
Increased NKX6.1 expression and decreased ARX expression in alpha cells accompany reduced beta-cell volume in human subjects
Fujita, Yukari, Kozawa, Junji, Fukui, Kenji, Iwahashi, Hiromi, Eguchi, Hidetoshi, Shimomura, Iichiro
Published in Scientific reports (07.09.2021)
Published in Scientific reports (07.09.2021)
Get full text
Journal Article
Problematic internet use and psychiatric co-morbidity in a population of Japanese adult psychiatric patients
de Vries, Hille T, Nakamae, Takashi, Fukui, Kenji, Denys, Damiaan, Narumoto, Jin
Published in BMC psychiatry (17.01.2018)
Published in BMC psychiatry (17.01.2018)
Get full text
Journal Article
A Histological Study of Fulminant Type 1 Diabetes Mellitus Related to Human Cytomegalovirus Reactivation
Yoneda, Sho, Imagawa, Akihisa, Fukui, Kenji, Uno, Sae, Kozawa, Junji, Sakai, Makoto, Yumioka, Toshiki, Iwahashi, Hiromi, Shimomura, Iichiro
Published in The journal of clinical endocrinology and metabolism (01.07.2017)
Published in The journal of clinical endocrinology and metabolism (01.07.2017)
Get full text
Journal Article
JTZ-951, an HIF prolyl hydroxylase inhibitor, suppresses renal interstitial fibroblast transformation and expression of fibrosis-related factors
Wakashima, Takeshi, Tanaka, Tetsuhiro, Fukui, Kenji, Komoda, Yasumasa, Shinozaki, Yuichi, Kobayashi, Hatsue, Matsuo, Akira, Nangaku, Masaomi
Published in American journal of physiology. Renal physiology (01.01.2020)
Published in American journal of physiology. Renal physiology (01.01.2020)
Get full text
Journal Article
Catalytic properties and crystal structure of UDP-galactose 4-epimerase-like l-threonine 3-dehydrogenase from Phytophthora infestans
Yoneda, Kazunari, Nagano, Rina, Mikami, Takuya, Sakuraba, Haruhiko, Fukui, Kenji, Araki, Tomohiro, Ohshima, Toshihisa
Published in Enzyme and microbial technology (01.10.2020)
Published in Enzyme and microbial technology (01.10.2020)
Get full text
Journal Article
Preoperative hemoglobin A1c is associated with postoperative bleeding after vitrectomy for vitreous hemorrhage in patients with diabetic retinopathy
Motoda, Saori, Kanai, Masanori, Sakimoto, Susumu, Ozawa, Harutoshi, Ishibashi, Chisaki, Fujita, Shingo, Hosokawa, Yoshiya, Baden, Megu Y., Fujita, Yukari, Kimura, Takekazu, Tokunaga, Ayumi, Nammo, Takao, Fukui, Kenji, Kozawa, Junji, Sakaguchi, Hirokazu, Nishida, Kohji, Shimomura, Iichiro
Published in Endocrine Journal (01.01.2024)
Published in Endocrine Journal (01.01.2024)
Get full text
Journal Article
Serial femtosecond X‐ray crystallography of an anaerobically formed catalytic intermediate of copper amine oxidase
Murakawa, Takeshi, Suzuki, Mamoru, Fukui, Kenji, Masuda, Tetsuya, Sugahara, Michihiro, Tono, Kensuke, Tanaka, Tomoyuki, Iwata, So, Nango, Eriko, Yano, Takato, Tanizawa, Katsuyuki, Okajima, Toshihide
Published in Acta crystallographica. Section D, Biological crystallography. (01.12.2022)
Published in Acta crystallographica. Section D, Biological crystallography. (01.12.2022)
Get full text
Journal Article
A Lynch syndrome-associated mutation at a Bergerat ATP-binding fold destabilizes the structure of the DNA mismatch repair endonuclease MutL
Izuhara, Keisuke, Fukui, Kenji, Murakawa, Takeshi, Baba, Seiki, Kumasaka, Takashi, Uchiyama, Kazuhisa, Yano, Takato
Published in The Journal of biological chemistry (14.08.2020)
Published in The Journal of biological chemistry (14.08.2020)
Get full text
Journal Article
Brain atrophy in the visual cortex and thalamus induced by severe stress in animal model
Yoshii, Takanobu, Oishi, Naoya, Ikoma, Kazuya, Nishimura, Isao, Sakai, Yuki, Matsuda, Kenichi, Yamada, Shunji, Tanaka, Masaki, Kawata, Mitsuhiro, Narumoto, Jin, Fukui, Kenji
Published in Scientific reports (06.10.2017)
Published in Scientific reports (06.10.2017)
Get full text
Journal Article
Pancreatic fat is related to the longitudinal decrease in the increment of C‐peptide in glucagon stimulation test in type 2 diabetes patients
Ishibashi, Chisaki, Kozawa, Junji, Hosakawa, Yoshiya, Yoneda, Sho, Kimura, Takekazu, Fujita, Yukari, Fukui, Kenji, Iwahashi, Hiromi, Shimomura, Iichiro
Published in Journal of diabetes investigation (01.01.2020)
Published in Journal of diabetes investigation (01.01.2020)
Get full text
Journal Article
Crystal structure of a nucleotide-binding domain of fatty acid kinase FakA from Thermus thermophilus HB8
Nakatani, Maya, Nakahara, Shun-ya, Fukui, Kenji, Urano, Momoka, Fujii, Yuki, Murakawa, Takeshi, Baba, Seiki, Kumasaka, Takashi, Okanishi, Hiroki, Kanai, Yoshikatsu, Yano, Takato, Masui, Ryoji
Published in Journal of structural biology (01.12.2022)
Published in Journal of structural biology (01.12.2022)
Get full text
Journal Article