Discovery of 1-oxa-4,9-diazaspiro[5.5]undecane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase inhibitors and orally active drug candidates for treating of chronic kidney diseases
Kato, Yuko, Fuchi, Nobuhiro, Nishimura, Yutaka, Watanabe, Ayano, Yagi, Mai, Nakadera, Yasuhito, Higashi, Eriko, Yamada, Masateru, Aoki, Takumi, Kigoshi, Hideo
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
Published in Bioorganic & medicinal chemistry letters (15.01.2014)
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Journal Article
Discovery of 2,8-diazaspiro[4.5]decane-based trisubstituted urea derivatives as highly potent soluble epoxide hydrolase inhibitors and orally active drug candidates for treating hypertension
Kato, Yuko, Fuchi, Nobuhiro, Saburi, Hajime, Nishimura, Yutaka, Watanabe, Ayano, Yagi, Mai, Nakadera, Yasuhito, Higashi, Eriko, Yamada, Masateru, Aoki, Takumi
Published in Bioorganic & medicinal chemistry letters (01.11.2013)
Published in Bioorganic & medicinal chemistry letters (01.11.2013)
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Journal Article
The Effects of a Selective CK2 Inhibitor on Anti-glomerular Basement Membrane Glomerulonephritis in Rats
Shi, Junfeng, Liu, Ning, Xiao, Ying, Takei, Yoshinori, Yasue, Misato, Suzuki, Yamato, Hou, Zengye, Ohno, Hiroaki, Yamada, Masateru, Fuchi, Nobuhiro, Oshida, Keiyu, Miyamoto, Yohei, Tsujimoto, Gozoh, Hirasawa, Akira
Published in Biological & pharmaceutical bulletin (01.09.2015)
Published in Biological & pharmaceutical bulletin (01.09.2015)
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Journal Article
Discovery and structure–activity relationship of 2,6-disubstituted pyrazines, potent and selective inhibitors of protein kinase CK2
Fuchi, Nobuhiro, Iura, Yosuke, Kaneko, Hiroaki, Nitta, Aiko, Suyama, Kazuharu, Ueda, Hiroshi, Yamaguchi, Shinichi, Nishimura, Kazumi, Fujii, Shigeo, Sekiya, Yumiko, Yamada, Masateru, Takahashi, Toshiya
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
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Journal Article
Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy
Brak, Katrien, Kerr, Iain D, Barrett, Kimberly T, Fuchi, Nobuhiro, Debnath, Moumita, Ang, Kenny, Engel, Juan C, McKerrow, James H, Doyle, Patricia S, Brinen, Linda S, Ellman, Jonathan A
Published in Journal of medicinal chemistry (25.02.2010)
Published in Journal of medicinal chemistry (25.02.2010)
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Journal Article
AGENT FOR TREATING OR PREVENTING SKIN DISORDER CAUSED BY ANTICANCER AGENT ADMINISTRATION
KAMATA YAYOI, TOMINAGA MITSUTOSHI, FUCHI NOBUHIRO, TAKAMORI KENJI, YAMADA HISAHIRO
Year of Publication 04.02.2021
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Year of Publication 04.02.2021
Patent
DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF
KATO, YUKO, AOKI, TAKUMI, SABURI, HAJIME, YAMADA, MASATERU, FUCHI, NOBUHIRO
Year of Publication 10.05.2013
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Year of Publication 10.05.2013
Patent
CYCLOHEXANEDIAMIDE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES
KATO, YUKO, KUROSAWA, SATOSHI, AOKI, TAKUMI, YAMADA, MASATERU, NISHIMURA, YUTAKA, FUCHI, NOBUHIRO, YAMADA, NAOHIRO
Year of Publication 31.10.2013
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Year of Publication 31.10.2013
Patent
The synthesis of beta-strand mimetic templates via regioselective 1,3-dipolar cycloaddition with vinylsulfone
Fuchi, N, Doi, T, Harada, T, Urban, J, Cao, BL, Kahn, M, Takahashi, T
Published in Tetrahedron letters (12.02.2001)
Published in Tetrahedron letters (12.02.2001)
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Journal Article
PYRAZINE DERIVATIVE AND NEPHRITIS-TREATING MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT
KANEKO HIROAKI, IURA YOSUKE, FUCHI NOBUHIRO, YAMADA MASATERU, SEKIYA YUMIKO
Year of Publication 14.06.2007
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Year of Publication 14.06.2007
Patent