Synthesis and evaluation of isothiazolo[4,5- b ]pyridines as cyclin G-associated kinase (GAK) inhibitors
Ivanova, Yulia, Spittaels, Sander, Gao, Ling-Jie, Schols, Dominique, Van Meervelt, Luc, Froeyen, Mathy, Dehaen, Wim, De Jonghe, Steven
Published in Organic & biomolecular chemistry (18.09.2024)
Published in Organic & biomolecular chemistry (18.09.2024)
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Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral
Delang, Leen, Segura Guerrero, Nidya, Tas, Ali, Quérat, Gilles, Pastorino, Boris, Froeyen, Mathy, Dallmeier, Kai, Jochmans, Dirk, Herdewijn, Piet, Bello, Felio, Snijder, Eric J, de Lamballerie, Xavier, Martina, Byron, Neyts, Johan, van Hemert, Martijn J, Leyssen, Pieter
Published in Journal of antimicrobial chemotherapy (01.10.2014)
Published in Journal of antimicrobial chemotherapy (01.10.2014)
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Synthesis of a 3,7-Disubstituted Isothiazolo[4,3- b ]pyridine as a Potential Inhibitor of Cyclin G-Associated Kinase
Grisez, Tom, Ravi, Nitha Panikkassery, Froeyen, Mathy, Schols, Dominique, Van Meervelt, Luc, De Jonghe, Steven, Dehaen, Wim
Published in Molecules (Basel, Switzerland) (22.02.2024)
Published in Molecules (Basel, Switzerland) (22.02.2024)
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Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase
Abdelnabi, Rana, Morais, Ana Theresa Silveira de, Leyssen, Pieter, Imbert, Isabelle, Beaucourt, Stéphanie, Blanc, Hervé, Froeyen, Mathy, Vignuzzi, Marco, Canard, Bruno, Neyts, Johan, Delang, Leen
Published in Journal of virology (15.06.2017)
Published in Journal of virology (15.06.2017)
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Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins
Vanmeert, Michiel, Razzokov, Jamoliddin, Mirza, Muhammad Usman, Weeks, Stephen D, Schepers, Guy, Bogaerts, Annemie, Rozenski, Jef, Froeyen, Mathy, Herdewijn, Piet, Pinheiro, Vitor B, Lescrinier, Eveline
Published in Nucleic acids research (26.07.2019)
Published in Nucleic acids research (26.07.2019)
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Frontispiece: Chimeric XNA: An Unconventional Design for Orthogonal Informational Systems
Efthymiou, Tim, Gavette, Jesse, Stoop, Matthias, De Riccardis, Francesco, Froeyen, Mathy, Herdewijn, Piet, Krishnamurthy, Ramanarayanan
Published in Chemistry : a European journal (03.09.2018)
Published in Chemistry : a European journal (03.09.2018)
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Binary Genetic Cassettes for Selecting XNA-Templated DNA Synthesis In Vivo
Pezo, Valérie, Liu, Feng Wu, Abramov, Mikhail, Froeyen, Mathy, Herdewijn, Piet, Marlière, Philippe
Published in Angewandte Chemie (International ed.) (29.07.2013)
Published in Angewandte Chemie (International ed.) (29.07.2013)
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Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polymerase
Musiu, Simone, Castillo, Yunierkis Perez, Muigg, Alexandra, Pürstinger, Gerhard, Leyssen, Pieter, Froeyen, Mathy, Neyts, Johan, Paeshuyse, Jan
Published in Molecules (Basel, Switzerland) (12.03.2020)
Published in Molecules (Basel, Switzerland) (12.03.2020)
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1′,5′-Anhydro‑l-ribo-hexitol Adenine Nucleic Acids (α‑l‑HNA-A): Synthesis and Chiral Selection Properties in the Mirror Image World
D’Alonzo, Daniele, Froeyen, Mathy, Schepers, Guy, Di Fabio, Giovanni, Van Aerschot, Arthur, Herdewijn, Piet, Palumbo, Giovanni, Guaragna, Annalisa
Published in Journal of organic chemistry (15.05.2015)
Published in Journal of organic chemistry (15.05.2015)
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A Derivate of the Antibiotic Doxorubicin Is a Selective Inhibitor of Dengue and Yellow Fever Virus Replication In Vitro
KAPTEIN, Suzanne J. F, DE BURGHGRAEVE, Tine, GAMARNIK, Andrea V, SZTARICSKAI, Ferenc, NEYTS, Johan, FROEYEN, Mathy, PASTORINO, Boris, ALEN, Marijke M. F, MONDOTTE, Juan A, HERDEWIJN, Piet, JACOBS, Michael, DE LAMBALLERIE, Xavier, SCHOLS, Dominique
Published in Antimicrobial Agents and Chemotherapy (01.12.2010)
Published in Antimicrobial Agents and Chemotherapy (01.12.2010)
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Galactosylsphingamides: new α-GalCer analogues to probe the F'-pocket of CD1d
Guillaume, Joren, Wang, Jing, Janssens, Jonas, Remesh, Soumya G, Risseeuw, Martijn D P, Decruy, Tine, Froeyen, Mathy, Elewaut, Dirk, Zajonc, Dirk M, Calenbergh, Serge Van
Published in Scientific reports (27.06.2017)
Published in Scientific reports (27.06.2017)
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1-(Piperidin-3-yl)thymine amides as inhibitors of M. tuberculosis thymidylate kinase
Jian, Yanlin, Risseeuw, Martijn D. P., Froeyen, Mathy, Song, Lijun, Cappoen, Davie, Cos, Paul, Munier-Lehmann, Hélène, van Calenbergh, Serge
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
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N-alkylated aminoacyl sulfamoyladenosines as potential inhibitors of aminoacylation reactions and microcin C analogues containing D-amino acids
Vondenhoff, Gaston H, Pugach, Ksenia, Gadakh, Bharat, Carlier, Laurence, Rozenski, Jef, Froeyen, Mathy, Severinov, Konstantin, Van Aerschot, Arthur
Published in PloS one (04.11.2013)
Published in PloS one (04.11.2013)
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Hybridisation potential of 1',3'-Di-O-methylaltropyranoside nucleic acids
Venkatesham, Akkaladevi, Kachare, Dhuldeo, Schepers, Guy, Rozenski, Jef, Froeyen, Mathy, Van Aerschot, Arthur
Published in Molecules (Basel, Switzerland) (03.03.2015)
Published in Molecules (Basel, Switzerland) (03.03.2015)
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Journal Article
Synthesis and evaluation of isothiazolo4,5-bpyridines as cyclin G-associated kinase (GAK) inhibitors
Ivanova, Yulia, Spittaels, Sander, Gao, Ling-Jie, Schols, Dominique, Van Meervelt, Luc, Froeyen, Mathy, Dehaen, Wim, De Jonghe, Steven
Published in Organic & biomolecular chemistry (18.09.2024)
Published in Organic & biomolecular chemistry (18.09.2024)
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The capsid binder Vapendavir and the novel protease inhibitor SG85 inhibit enterovirus 71 replication
Tijsma, Aloys, Franco, David, Tucker, Simon, Hilgenfeld, Rolf, Froeyen, Mathy, Leyssen, Pieter, Neyts, Johan
Published in Antimicrobial agents and chemotherapy (01.11.2014)
Published in Antimicrobial agents and chemotherapy (01.11.2014)
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Structural insights into the morpholino nucleic acid/RNA duplex using the new XNA builder Ducque in a molecular modeling pipeline
Rihon, Jérôme, Mattelaer, Charles-Alexandre, Montalvão, Rinaldo Wander, Froeyen, Mathy, Pinheiro, Vitor Bernardes, Lescrinier, Eveline
Published in Nucleic acids research (12.04.2024)
Published in Nucleic acids research (12.04.2024)
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