Abstract 2212: Super-enhancer landscapes specify molecular subtypes and novel targets in acute myeloid leukemia
Eaton, Matthew, Corces-Zimmerman, Ryan, Lopez, Jeremy, Fritz, Christian, Olson, Eric, Majeti, Ravindra, Loven, Jakob
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Specifying and computing preferred plans
Bienvenu, Meghyn, Fritz, Christian, McIlraith, Sheila A.
Published in Artificial intelligence (01.05.2011)
Published in Artificial intelligence (01.05.2011)
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Abstract B171: PK/PD modeling of the first-in-class, potent and selective covalent CDK7 inhibitor, SY-1365, provides mechanistic basis for intermittent dosing regimens in preclinical efficacy models of hematologic and solid tumors
Waters, Nigel J., Hu, Shanhu, Matzuka, Brett, Hodgson, Graeme, Ren, Yixuan, Choi, Yoon, Dykstra, Kevin, Roberts, Christopher, Sprott, Kevin, di Tomaso, Emmanuelle, Fritz, Christian
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Abstract 1511: AML patient clustering by super-enhancers reveals an RARA associated transcription factor signaling partner
McKeown, Michael R., Eaton, Matthew L., Fiore, Chris, Lee, Emily, Austgen, Katie, Smith, Darren, Corces, M. Ryan, Majeti, Ravindra, Fritz, Christian C.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract 1143: Targeting the transcriptional kinases CDK12 and CDK13 in breast and ovarian cancer
Bradley, Michael, Marineau, Jason, Choi, Yoon, Hamman, Kristin, Malojcic, Goran, Orlando, David, Ren, Yixuan, Ke, Nan, Hu, Shanhu, Olson, Eric, Fritz, Christian, Roberts, Christopher
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract 1151: SY-1365, a potent and selective CDK7 inhibitor, exhibits promising anti-tumor activity in multiple preclinical models of aggressive solid tumors
Hu, Shanhu, Ke, Nan, Ren, Yixuan, Miljovska, Sofija, Rajagopal, Nisha, McKeown, Michael, Orlando, David, Sprott, Kevin, Choi, Yoon J., Olson, Eric, Fritz, Christian C.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract 1525: SY-1365, a selective CDK7 inhibitor, exhibits potent antitumor activity against ovarian cancer models in vitro and in vivo
Konstantinopoulos, Panagiotis A., Hodgson, Graeme, Rajagopal, Nisha, Johannessen, Liv, Liu, Joyce F., Kirschmeier, Paul T., Zhou, Shan, Tran, Cam Anh, Orlando, David, Fritz, Christian, Tomaso, Emmanuelle di, Matulonis, Ursula A.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Synthetic Silvestrol Analogues as Potent and Selective Protein Synthesis Inhibitors
Liu, Tao, Nair, Somarajan J, Lescarbeau, André, Belani, Jitendra, Peluso, Stéphane, Conley, James, Tillotson, Bonnie, O’Hearn, Patrick, Smith, Sherri, Slocum, Kelly, West, Kip, Helble, Joseph, Douglas, Mark, Bahadoor, Adilah, Ali, Janid, McGovern, Karen, Fritz, Christian, Palombella, Vito J, Wylie, Andrew, Castro, Alfredo C, Tremblay, Martin R
Published in Journal of medicinal chemistry (25.10.2012)
Published in Journal of medicinal chemistry (25.10.2012)
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Myelolipoma: A rare but important differential diagnosis of accidentally detected fatty retroperitoneal and adrenal masses
Yildiz, Selcuk Murat, Krombach, Gabriele Anja, Roller, Fritz Christian
Published in RöFo : Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebende Verfahren (01.01.2022)
Published in RöFo : Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebende Verfahren (01.01.2022)
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Optimization of Whole-Body CT Examinations of Polytrauma Patients in Comparison with the Current Diagnostic Reference Levels
Schäfer, Stefan B., Rudolph, Claudia, Kolodziej, Martin, Mauermann, Frank, Roller, Fritz Christian, Krombach, Gabriele Anja
Published in RöFo : Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebende Verfahren (01.11.2019)
Published in RöFo : Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebende Verfahren (01.11.2019)
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Abstract PR05: SY-1425 (tamibarotene), a potent and selective RARα agonist, induces changes in the transcriptional regulatory circuit of AML cells leading to differentiation
Fiore, Christopher M., McKeown, Michael R., Lee, Emily, Eaton, Matthew L., Smith, Darren, Austgen, Kathryn, Chen, Mei Wei, Guenther, Matthew, Corces, M. Ryan, Majeti, Ravindra, Olson, Eric, Fritz, Christian C.
Published in Clinical cancer research (15.12.2017)
Published in Clinical cancer research (15.12.2017)
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Abstract 3837: Super-enhancers define breast cancer subclasses and identify novel tumor cell vulnerabilities
Collins, Cindy, Chen, Mei Wei, Eaton, Matthew, Orlando, David, McKeown, Michael, Fritz, Christian, Olson, Eric, Guenther, Matthew
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Symbiosis revisited: phosphorus and acid buffering stimulate N2 fixation but not Sphagnum growth
van den Elzen, Eva, Kox, Martine A R, Harpenslager, Sarah F, Hensgens, Geert, Fritz, Christian, Jetten, Mike S M, Ettwig, Katharina F, Lamers, Leon P M
Published in Biogeosciences (01.03.2017)
Published in Biogeosciences (01.03.2017)
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Abstract 1187: Discovery of new AML and MDS patient subsets sensitive to the highly selective RARα agonist SY-1425 (tamibarotene) through super-enhancer analysis
McKeown, Michael R., Lee, Emily, Fiore, Chris, Eaton, Matthew L., Lopez, Jeremy, Corces-Zimmerman, Ryan, Majeti, Ravindra, Fritz, Christian, Olson, Eric
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Discovery and Characterization of Super-Enhancer-Associated Dependencies in Acute Myeloid Leukemia
Corces-Zimmerman, Michael Ryan, Eaton, Matthew, Lopez, Jeremy, Ke, Nan, Fritz, Christian, Olson, Eric, Majeti, Ravi, Loven, Jakob
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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