The role of mitochondria in the oncogenic signal transduction
Frezza, Christian
Published in The international journal of biochemistry & cell biology (01.03.2014)
Published in The international journal of biochemistry & cell biology (01.03.2014)
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Journal Article
Metabolic synthetic lethality in cancer therapy
Zecchini, Vincent, Frezza, Christian
Published in Biochimica et biophysica acta. Bioenergetics (01.08.2017)
Published in Biochimica et biophysica acta. Bioenergetics (01.08.2017)
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Journal Article
A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury
Chouchani, Edward T., Pell, Victoria R., James, Andrew M., Work, Lorraine M., Saeb-Parsy, Kourosh, Frezza, Christian, Krieg, Thomas, Murphy, Michael P.
Published in Cell metabolism (09.02.2016)
Published in Cell metabolism (09.02.2016)
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Journal Article
Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
Fernandez-Antoran, David, Piedrafita, Gabriel, Murai, Kasumi, Ong, Swee Hoe, Herms, Albert, Frezza, Christian, Jones, Philip H.
Published in Cell stem cell (05.09.2019)
Published in Cell stem cell (05.09.2019)
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Journal Article
Predicting selective drug targets in cancer through metabolic networks
Folger, Ori, Jerby, Livnat, Frezza, Christian, Gottlieb, Eyal, Ruppin, Eytan, Shlomi, Tomer
Published in Molecular systems biology (21.06.2011)
Published in Molecular systems biology (21.06.2011)
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Journal Article
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
Mills, Evanna L., Kelly, Beth, Logan, Angela, Costa, Ana S.H., Varma, Mukund, Bryant, Clare E., Tourlomousis, Panagiotis, Däbritz, J. Henry M., Gottlieb, Eyal, Latorre, Isabel, Corr, Sinéad C., McManus, Gavin, Ryan, Dylan, Jacobs, Howard T., Szibor, Marten, Xavier, Ramnik J., Braun, Thomas, Frezza, Christian, Murphy, Michael P., O’Neill, Luke A.
Published in Cell (06.10.2016)
Published in Cell (06.10.2016)
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Journal Article
Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency
Cogliati, Sara, Frezza, Christian, Soriano, Maria Eugenia, Varanita, Tatiana, Quintana-Cabrera, Ruben, Corrado, Mauro, Cipolat, Sara, Costa, Veronica, Casarin, Alberto, Gomes, Ligia C., Perales-Clemente, Ester, Salviati, Leonardo, Fernandez-Silva, Patricio, Enriquez, Jose A., Scorrano, Luca
Published in Cell (26.09.2013)
Published in Cell (26.09.2013)
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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Chouchani, Edward T., Pell, Victoria R., Gaude, Edoardo, Aksentijević, Dunja, Sundier, Stephanie Y., Robb, Ellen L., Logan, Angela, Nadtochiy, Sergiy M., Ord, Emily N. J., Smith, Anthony C., Eyassu, Filmon, Shirley, Rachel, Hu, Chou-Hui, Dare, Anna J., James, Andrew M., Rogatti, Sebastian, Hartley, Richard C., Eaton, Simon, Costa, Ana S. H., Brookes, Paul S., Davidson, Sean M., Duchen, Michael R., Saeb-Parsy, Kourosh, Shattock, Michael J., Robinson, Alan J., Work, Lorraine M., Frezza, Christian, Krieg, Thomas, Murphy, Michael P.
Published in Nature (London) (20.11.2014)
Published in Nature (London) (20.11.2014)
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Journal Article
Neural stem cells traffic functional mitochondria via extracellular vesicles
Peruzzotti-Jametti, Luca, Bernstock, Joshua D, Willis, Cory M, Manferrari, Giulia, Rogall, Rebecca, Fernandez-Vizarra, Erika, Williamson, James C, Braga, Alice, van den Bosch, Aletta, Leonardi, Tommaso, Krzak, Grzegorz, Kittel, Ágnes, Benincá, Cristiane, Vicario, Nunzio, Tan, Sisareuth, Bastos, Carlos, Bicci, Iacopo, Iraci, Nunzio, Smith, Jayden A, Peacock, Ben, Muller, Karin H, Lehner, Paul J, Buzas, Edit Iren, Faria, Nuno, Zeviani, Massimo, Frezza, Christian, Brisson, Alain, Matheson, Nicholas J, Viscomi, Carlo, Pluchino, Stefano
Published in PLoS biology (07.04.2021)
Published in PLoS biology (07.04.2021)
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Journal Article
Convergent somatic mutations in metabolism genes in chronic liver disease
Ng, Stanley W. K., Rouhani, Foad J., Brunner, Simon F., Brzozowska, Natalia, Aitken, Sarah J., Yang, Ming, Abascal, Federico, Moore, Luiza, Nikitopoulou, Efterpi, Chappell, Lia, Leongamornlert, Daniel, Ivovic, Aleksandra, Robinson, Philip, Butler, Timothy, Sanders, Mathijs A., Williams, Nicholas, Coorens, Tim H. H., Teague, Jon, Raine, Keiran, Butler, Adam P., Hooks, Yvette, Wilson, Beverley, Birtchnell, Natalie, Naylor, Huw, Davies, Susan E., Stratton, Michael R., Martincorena, Iñigo, Rahbari, Raheleh, Frezza, Christian, Hoare, Matthew, Campbell, Peter J.
Published in Nature (London) (21.10.2021)
Published in Nature (London) (21.10.2021)
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Journal Article
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
Chaneton, Barbara, Hillmann, Petra, Zheng, Liang, Martin, Agnès C. L., Maddocks, Oliver D. K., Chokkathukalam, Achuthanunni, Coyle, Joseph E., Jankevics, Andris, Holding, Finn P., Vousden, Karen H., Frezza, Christian, O’Reilly, Marc, Gottlieb, Eyal
Published in Nature (London) (15.11.2012)
Published in Nature (London) (15.11.2012)
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Journal Article
Cancer associated fibroblast FAK regulates malignant cell metabolism
Demircioglu, Fevzi, Wang, Jun, Candido, Juliana, Costa, Ana S. H., Casado, Pedro, de Luxan Delgado, Beatriz, Reynolds, Louise E., Gomez-Escudero, Jesus, Newport, Emma, Rajeeve, Vinothini, Baker, Ann-Marie, Roy-Luzarraga, Marina, Graham, Trevor A., Foster, Julie, Wang, Yu, Campbell, James J., Singh, Rajinder, Zhang, Penglie, Schall, Thomas J., Balkwill, Frances R., Sosabowski, Jane, Cutillas, Pedro R., Frezza, Christian, Sancho, Patricia, Hodivala-Dilke, Kairbaan
Published in Nature communications (10.03.2020)
Published in Nature communications (10.03.2020)
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Journal Article
Inborn and acquired metabolic defects in cancer
Frezza, Christian, Pollard, Patrick J, Gottlieb, Eyal
Published in Journal of molecular medicine (Berlin, Germany) (01.03.2011)
Published in Journal of molecular medicine (Berlin, Germany) (01.03.2011)
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Journal Article
Fumarate induces redox-dependent senescence by modifying glutathione metabolism
Zheng, Liang, Cardaci, Simone, Jerby, Livnat, MacKenzie, Elaine D., Sciacovelli, Marco, Johnson, T. Isaac, Gaude, Edoardo, King, Ayala, Leach, Joshua D. G., Edrada-Ebel, RuAngelie, Hedley, Ann, Morrice, Nicholas A., Kalna, Gabriela, Blyth, Karen, Ruppin, Eytan, Frezza, Christian, Gottlieb, Eyal
Published in Nature communications (23.01.2015)
Published in Nature communications (23.01.2015)
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