The RNA export and RNA decay complexes THO and TRAMP prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions
Brown, Rebecca E, Su, Xiaofeng A, Fair, Stacey, Wu, Katherine, Verra, Lauren, Jong, Robyn, Andrykovich, Kristin, Freudenreich, Catherine H
Published in PLoS biology (27.12.2022)
Published in PLoS biology (27.12.2022)
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Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability
Su, Xiaofeng A, Dion, Vincent, Gasser, Susan M, Freudenreich, Catherine H
Published in Genes & development (15.05.2015)
Published in Genes & development (15.05.2015)
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Repeat expansions confer WRN dependence in microsatellite-unstable cancers
van Wietmarschen, Niek, Sridharan, Sriram, Nathan, William J, Tubbs, Anthony, Chan, Edmond M, Callen, Elsa, Wu, Wei, Belinky, Frida, Tripathi, Veenu, Wong, Nancy, Foster, Kyla, Noorbakhsh, Javad, Garimella, Kiran, Cruz-Migoni, Abimael, Sommers, Joshua A, Huang, Yongqing, Borah, Ashir A, Smith, Jonathan T, Kalfon, Jeremie, Kesten, Nikolas, Fugger, Kasper, Walker, Robert L, Dolzhenko, Egor, Eberle, Michael A, Hayward, Bruce E, Usdin, Karen, Freudenreich, Catherine H, Brosh, Jr, Robert M, West, Stephen C, McHugh, Peter J, Meltzer, Paul S, Bass, Adam J, Nussenzweig, André
Published in Nature (London) (08.10.2020)
Published in Nature (London) (08.10.2020)
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What repeat expansion disorders can teach us about the Central Dogma
Wang, Eric T., Freudenreich, Catherine H., Gromak, Natalia, Jain, Ankur, Todd, Peter K., Nagai, Yoshitaka
Published in Molecular cell (02.02.2023)
Published in Molecular cell (02.02.2023)
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Chromatin modifications and DNA repair: beyond double-strand breaks
House, Nealia C M, Koch, Melissa R, Freudenreich, Catherine H
Published in Frontiers in genetics (05.09.2014)
Published in Frontiers in genetics (05.09.2014)
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Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes
Zhao, Junhua, Wang, Guliang, del Mundo, Imee M., McKinney, Jennifer A., Lu, Xiuli, Bacolla, Albino, Boulware, Stephen B., Zhang, Changsheng, Zhang, Haihua, Ren, Pengyu, Freudenreich, Catherine H., Vasquez, Karen M.
Published in Cell reports (Cambridge) (30.01.2018)
Published in Cell reports (Cambridge) (30.01.2018)
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Overcoming natural replication barriers: differential helicase requirements
Anand, Ranjith P., Shah, Kartik A., Niu, Hengyao, Sung, Patrick, Mirkin, Sergei M., Freudenreich, Catherine H.
Published in Nucleic acids research (01.02.2012)
Published in Nucleic acids research (01.02.2012)
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Distinct roles for S. cerevisiae H2A copies in recombination and repeat stability, with a role for H2A.1 threonine 126
House, Nealia Cm, Polleys, Erica J, Quasem, Ishtiaque, De la Rosa Mejia, Marjorie, Joyce, Cailin E, Takacsi-Nagy, Oliver, Krebs, Jocelyn E, Fuchs, Stephen M, Freudenreich, Catherine H
Published in eLife (05.12.2019)
Published in eLife (05.12.2019)
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Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast
Cherng, Nicole, Shishkin, Alexander A., Schlager, Lucas I., Tuck, Ryan H., Sloan, Laura, Matera, Robert, Sarkar, Partha S., Ashizawa, Tetsuo, Freudenreich, Catherine H., Mirkin, Sergei M., Petes, Thomas D.
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (15.02.2011)
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