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Published in JNCI : Journal of the National Cancer Institute (21.03.2001)
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Potent Antagonists of the SH2 Domain of Grb2: Optimization of the X+1 Position of 3-Amino-Z-Tyr(PO3H2)-X+1-Asn-NH2
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Published in Journal of medicinal chemistry (21.05.1998)
Published in Journal of medicinal chemistry (21.05.1998)
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Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode
Rahuel, J, Gay, B, Erdmann, D, Strauss, A, Garcia-Echeverría, C, Furet, P, Caravatti, G, Fretz, H, Schoepfer, J, Grütter, M G
Published in Nature structural biology (01.07.1996)
Published in Nature structural biology (01.07.1996)
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Protein kinases as targets for anticancer agents: from inhibitors to useful drugs
Fabbro, Doriano, Ruetz, Stephan, Buchdunger, Elisabeth, Cowan-Jacob, Sandra W, Fendrich, Gabriele, Liebetanz, Janis, Mestan, Jürgen, O'Reilly, Terence, Traxler, Peter, Chaudhuri, Bhabatosh, Fretz, Heinz, Zimmermann, Jürg, Meyer, Thomas, Caravatti, Giorgio, Furet, Pascal, Manley, Paul W
Published in Pharmacology & therapeutics (Oxford) (01.02.2002)
Published in Pharmacology & therapeutics (Oxford) (01.02.2002)
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Inhibition of Cyclin-Dependent Kinase 4 (Cdk4) by Fascaplysin, a Marine Natural Product
Soni, Rajeev, Muller, Lionel, Furet, Pascal, Schoepfer, Joseph, Stephan, Christine, Zumstein-Mecker, Sabine, Fretz, Heinz, Chaudhuri, Bhabatosh
Published in Biochemical and biophysical research communications (07.09.2000)
Published in Biochemical and biophysical research communications (07.09.2000)
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DNA binding properties of the marine sponge pigment fascaplysin
Hörmann, Aldo, Chaudhuri, Bhabatosh, Fretz, Heinz
Published in Bioorganic & medicinal chemistry (01.04.2001)
Published in Bioorganic & medicinal chemistry (01.04.2001)
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Structure-Based Design and Synthesis of 2-Benzylidene-benzofuran-3-ones as Flavopiridol Mimics
Schoepfer, Joseph, Fretz, Heinz, Chaudhuri, Bhabatosh, Muller, Lionel, Seeber, Egge, Meijer, Laurent, Lozach, Olivier, Vangrevelinghe, Eric, Furet, Pascal
Published in Journal of medicinal chemistry (25.04.2002)
Published in Journal of medicinal chemistry (25.04.2002)
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Structure-based design and synthesis of nigh affinity tripeptide ligands of the Grb2-SH2 domain
Furet, P, Gay, B, Caravatti, G, Garcia-Echeverria, C, Rahuel, J, Schoepfer, J, Fretz, H
Published in Journal of medicinal chemistry (27.08.1998)
Published in Journal of medicinal chemistry (27.08.1998)
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Structure-Based Design and Synthesis of High Affinity Tripeptide Ligands of the Grb2-SH2 Domain
Furet, Pascal, Gay, Brigitte, Caravatti, Giorgio, García-Echeverría, Carlos, Rahuel, Joseph, Schoepfer, Joseph, Fretz, Heinz
Published in Journal of medicinal chemistry (27.08.1998)
Published in Journal of medicinal chemistry (27.08.1998)
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Discovery of 3-Aminobenzyloxycarbonyl as an N-Terminal Group Conferring High Affinity to the Minimal Phosphopeptide Sequence Recognized by the Grb2-SH2 Domain
Furet, Pascal, Gay, Brigitte, García-Echeverría, Carlos, Rahuel, Joseph, Fretz, Heinz, Schoepfer, Joseph, Caravatti, Giorgio
Published in Journal of medicinal chemistry (24.10.1997)
Published in Journal of medicinal chemistry (24.10.1997)
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Highly potent inhibitors of the Grb2-SH2 domain
Schoepfer, Joseph, Fretz, Heinz, Gay, Brigitte, Furet, Pascal, García-Echeverría, Carlos, End, Nicole, Caravatti, Giorgio
Published in Bioorganic & medicinal chemistry letters (18.01.1999)
Published in Bioorganic & medicinal chemistry letters (18.01.1999)
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Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands
Rahuel, Joseph, Garcı́a-Echeverrı́a, Carlos, Furet, Pascal, Strauss, André, Caravatti, Giorgio, Fretz, Heinz, Schoepfer, Joseph, Gay, Brigitte
Published in Journal of molecular biology (19.06.1998)
Published in Journal of molecular biology (19.06.1998)
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