Discovery of disubstituted phenanthrene imidazoles as potent, selective and orally active mPGES-1 inhibitors
Giroux, André, Boulet, Louise, Brideau, Christine, Chau, Anh, Claveau, David, Côté, Bernard, Ethier, Diane, Frenette, Richard, Gagnon, Marc, Guay, Jocelyne, Guiral, Sébastien, Mancini, Joseph, Martins, Evelyn, Massé, Frédéric, Méthot, Nathalie, Riendeau, Denis, Rubin, Joel, Xu, Daigen, Yu, Hongping, Ducharme, Yves, Friesen, Richard W.
Published in Bioorganic & medicinal chemistry letters (15.10.2009)
Published in Bioorganic & medicinal chemistry letters (15.10.2009)
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Journal Article
Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors
Côté, Bernard, Boulet, Louise, Brideau, Christine, Claveau, David, Ethier, Diane, Frenette, Richard, Gagnon, Marc, Giroux, André, Guay, Jocelyne, Guiral, Sébastien, Mancini, Joseph, Martins, Evelyn, Massé, Frédéric, Méthot, Nathalie, Riendeau, Denis, Rubin, Joel, Xu, Daigen, Yu, Hongping, Ducharme, Yves, Friesen, Richard W.
Published in Bioorganic & medicinal chemistry letters (15.12.2007)
Published in Bioorganic & medicinal chemistry letters (15.12.2007)
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Substituted 4-(2,2-diphenylethyl)pyridine-n-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters
FRENETTE, Richard, BLOUIN, Marc, MASSON, Paul, MCAULIFFE, Malia, GIRARD, Yves, BRIDEAU, Christine, CHAURET, Nathalie, DUCHARME, Yves, FRIESEN, Richard W, HAMEL, Pierre, JONES, Tom R, LALIBERTE, France, CHUN LI
Published in Bioorganic & medicinal chemistry letters (01.10.2002)
Published in Bioorganic & medicinal chemistry letters (01.10.2002)
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Substituted 2,2-bisaryl-bicycloheptanes as novel and potent inhibitors of 5-lipoxygenase activating protein
Macdonald, Dwight, Brideau, Christine, Chan, Chi Chung, Falgueyret, Jean-Pierre, Frenette, Richard, Guay, Jocelyne, Hutchinson, John H., Perrier, Hélène, Prasit, Peptiboon, Riendeau, Denis, Tagari, Philip, Thérien, Michel, Young, Robert N., Girard, Yves
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Direct synthesis of thio ethers from thiols and alcohols
Guindon, Yvan, Frenette, Richard, Fortin, Rejean, Rokach, Joshua
Published in Journal of organic chemistry (01.04.1983)
Published in Journal of organic chemistry (01.04.1983)
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METHODS, COMPOUNDS, AND COMPOSITIONS FOR DELIVERING 1,3-PROPANEDISULFONIC ACID
LEVENS NIGEL, BOUZIDE ABDERRAHIM, RENAUD JOHANNE, CIBLAT STEPHANE, FRENETTE RICHARD, KONG XIANQI
Year of Publication 07.08.2012
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Year of Publication 07.08.2012
Patent
Optimization of a Tertiary Alcohol Series of Phosphodiesterase-4 (PDE4) Inhibitors: Structure−Activity Relationship Related to PDE4 Inhibition and Human Ether-a-go-go Related Gene Potassium Channel Binding Affinity
Friesen, Richard W, Ducharme, Yves, Ball, Richard G, Blouin, Marc, Boulet, Louise, Côté, Bernard, Frenette, Richard, Girard, Mario, Guay, Daniel, Huang, Zheng, Jones, Thomas R, Laliberté, France, Lynch, Joseph J, Mancini, Joseph, Martins, Evelyn, Masson, Paul, Muise, Eric, Pon, Douglas J, Siegl, Peter K. S, Styhler, Angela, Tsou, Nancy N, Turner, Mervyn J, Young, Robert N, Girard, Yves
Published in Journal of medicinal chemistry (05.06.2003)
Published in Journal of medicinal chemistry (05.06.2003)
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2,3-Diarylthiophenes as selective EP1 receptor antagonists
DUCHARME, Yves, BLOUIN, Marc, MARTINS, Evelyn, NANTEL, Francois, O'NEILL, Gary, SAWYER, Nicole, METTERS, Kathleen M, FRIESEN, Richard W, CARRIERE, Marie-Claude, CHATEAUNEUF, Anne, COTE, Bernard, DENIS, Danielle, FRENETTE, Richard, GREIG, Gillian, KARGMAN, Stacia, LAMONTAGNE, Sonia
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
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Journal Article
Lack of Clinical Efficacy of a Phosphodiesterase-4 Inhibitor for Treatment of Heaves in Horses
Lavoie, Jean-Pierre, Pasloske, Kirby, Joubert, Philippe, Cordeau, Marie-Eve, Mancini, Joseph, Girard, Yves, Friesen, Richard W., Frenette, Richard, Blouin, Marc, Young, Robert N, Hickey, Gerry
Published in Journal of veterinary internal medicine (2006)
Published in Journal of veterinary internal medicine (2006)
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Flow and Erosive Stresses at the Base of a Headcut
Frenette, Richard, Pestov, Irène
Published in Journal of hydraulic engineering (New York, N.Y.) (01.02.2005)
Published in Journal of hydraulic engineering (New York, N.Y.) (01.02.2005)
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Unified Modeling of Fluid or Granular Flows on Dam-Break Case
Frenette, Richard, Zimmermann, Thomas, Eyheramendy, Dominique
Published in Journal of hydraulic engineering (New York, N.Y.) (01.03.2002)
Published in Journal of hydraulic engineering (New York, N.Y.) (01.03.2002)
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Comparison of inhibition of ovalbumin-induced bronchoconstriction in guinea pigs and in vitro inhibition of tumor necrosis factor-α formation with phosphodiesterase 4 (PDE4) selective inhibitors
Muise, Eric S, Chute, Ian C, Claveau, David, Masson, Paul, Boulet, Louise, Tkalec, Lydia, Pon, Douglas J, Girard, Yves, Frenette, Richard, Mancini, Joseph A
Published in Biochemical pharmacology (15.04.2002)
Published in Biochemical pharmacology (15.04.2002)
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Journal Article
Substituted 4-(2,2-diphenylethyl)pyridine-N-oxides as phosphodiesterase-4 inhibitors: SAR study directed toward the improvement of pharmacokinetic parameters
Frenette, Richard, Blouin, Marc, Brideau, Christine, Chauret, Nathalie, Ducharme, Yves, Friesen, Richard W, Hamel, Pierre, Jones, Tom R, Laliberté, France, Li, Chun, Masson, Paul, McAuliffe, Malia, Girard, Yves
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
Published in Bioorganic & medicinal chemistry letters (21.10.2002)
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Journal Article
2,3-Diarylthiophenes as selective EP 1 receptor antagonists
Ducharme, Yves, Blouin, Marc, Carrière, Marie-Claude, Chateauneuf, Anne, Côté, Bernard, Denis, Danielle, Frenette, Richard, Greig, Gillian, Kargman, Stacia, Lamontagne, Sonia, Martins, Evelyn, Nantel, François, O’Neill, Gary, Sawyer, Nicole, Metters, Kathleen M., Friesen, Richard W.
Published in Bioorganic & medicinal chemistry letters (2005)
Published in Bioorganic & medicinal chemistry letters (2005)
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Journal Article
Substituted 2-Pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors
Ducharme, Yves, Friesen, Richard W, Blouin, Marc, Côté, Bernard, Dubé, Daniel, Ethier, Diane, Frenette, Richard, Laliberté, France, Mancini, Joseph A, Masson, Paul, Styhler, Angela, Young, Robert N, Girard, Yves
Published in Bioorganic & medicinal chemistry letters (02.06.2003)
Published in Bioorganic & medicinal chemistry letters (02.06.2003)
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Journal Article
Lack of clinical efficacy of a phosphodiesterase-4 inhibitor for treatment of heaves in horses
Lavoie, J.P, Pasloske, K, Joubert, P, Cordeau, M.E, Mancini, J, Girard, Y, Friesen, R.W, Frenette, R, Blouin, M, Young, R.N
Published in Journal of veterinary internal medicine (2006)
Published in Journal of veterinary internal medicine (2006)
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Journal Article
Comparison of inhibition of ovalbumin-induced bronchoconstriction in guinea pigs and in vitro inhibition of tumor necrosis factor-oc formation with phosphodiesterase 4 (PDE4) selective inhibitors
MUISE, Eric S, CHUTE, Ian C, CLAVEAU, David, MASSON, Paul, BOULET, Louise, TKALEC, Lydia, PON, Douglas J, GIRARD, Yves, FRENETTE, Richard, MANCINI, Joseph A
Published in Biochemical pharmacology (2002)
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Published in Biochemical pharmacology (2002)
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