Development of a QSAR for worst case estimates of acute toxicity of chemically reactive compounds
Freidig, A.P., Dekkers, S., Verwei, M., Zvinavashe, E., Bessems, J.G.M., van de Sandt, J.J.M.
Published in Toxicology letters (15.05.2007)
Published in Toxicology letters (15.05.2007)
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Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents III. PBPK modeling of white spirit constituents as a tool for integrating animal and human test data
HISSINK, A. M, KRÜSE, J, MCKEE, R. H, KULIG, B. M, VERWEI, M, MUIJSER, H, SALMON, F, LEENHEERS, L. H, OWEN, D. E, LAMMERS, J. H. C. M, FREIDIG, A. P
Published in Neurotoxicology (Park Forest South) (01.07.2007)
Published in Neurotoxicology (Park Forest South) (01.07.2007)
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Comparing the Potency of Chemicals with Multiple Modes of Action in Aquatic Toxicology: Acute Toxicity Due to Narcosis versus Reactive Toxicity of Acrylic Compounds
Freidig, Andreas P, Verhaar, Henk J. M, Hermens, Joop L. M
Published in Environmental science & technology (01.09.1999)
Published in Environmental science & technology (01.09.1999)
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Estimating impact of humic acid on bioavailability and bioaccumulation of hydrophobic chemicals in guppies using kinetic solid-phase extraction
Freidig, A.P. (University of Utrecht, Utrecht, The Netherlands.), Garicano, A.E, Busser, F.J.M, Hermens, J.L.M
Published in Environmental toxicology and chemistry (01.06.1998)
Published in Environmental toxicology and chemistry (01.06.1998)
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Journal Article
Physiologically based pharmacokinetic modeling of cyclohexane as a tool for integrating animal and human test data
Hissink, A M, Kulig, B M, Kruse, J, Freidig, A P, Verwei, M, Muijser, H, Lammers, J H C M, McKee, R H, Owen, D E, Sweeney, L M, Salmon, F
Published in International journal of toxicology (01.11.2009)
Published in International journal of toxicology (01.11.2009)
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Clearance and clearance inhibition of the HIV-1 protease inhibitors ritonavir and saquinavir in sandwich-cultured rat hepatocytes and rat microsomes
Treijtel, N., Eijkeren, J.C.H. van, Nijmeijer, S., de Greef-van der Sandt, I.C.J., Freidig, A.P.
Published in Toxicology in vitro (01.02.2009)
Published in Toxicology in vitro (01.02.2009)
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Prediction of isoprene diepoxide levels in vivo in mouse, rat and man using enzyme kinetic data in vitro and physiologically-based pharmacokinetic modelling
Bogaards, Jan J.P, Freidig, Andreas P, van Bladeren, Peter J
Published in Chemico-biological interactions (21.12.2001)
Published in Chemico-biological interactions (21.12.2001)
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1-Octanol/water distribution coefficient of oxolinic acid: influence of pH and its relation to the interaction with dissolved organic carbon
Lützhøft, Hans-Christian Holten, Vaes, Wouter H.J, Freidig, Andreas P, Halling-Sørensen, Bent, Hermens, Joop L.M
Published in Chemosphere (Oxford) (01.04.2000)
Published in Chemosphere (Oxford) (01.04.2000)
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The use of in vitro metabolic parameters and physiologically based pharmacokinetic (PBPK) modeling to explore the risk assessment of trichloroethylene
Hissink, Erna M., Bogaards, Jan J.P., Freidig, Andreas P., Commandeur, Jan N.M., Vermeulen, Nico P.E., van Bladeren, Peter J.
Published in Environmental toxicology and pharmacology (01.07.2002)
Published in Environmental toxicology and pharmacology (01.07.2002)
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Dietary medium chain fatty acid supplementation leads to reduced VLDL lipolysis and uptake rates in comparison to linoleic acid supplementation
van Schalkwijk, Daniël B, Pasman, Wilrike J, Hendriks, Henk F J, Verheij, Elwin R, Rubingh, Carina M, van Bochove, Kees, Vaes, Wouter H J, Adiels, Martin, Freidig, Andreas P, de Graaf, Albert A
Published in PloS one (21.07.2014)
Published in PloS one (21.07.2014)
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A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat
Punt, Ans, Freidig, Andreas P., Delatour, Thierry, Scholz, Gabriele, Boersma, Marelle G., Schilter, Benoît, van Bladeren, Peter J., Rietjens, Ivonne M.C.M.
Published in Toxicology and applied pharmacology (01.09.2008)
Published in Toxicology and applied pharmacology (01.09.2008)
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Transcriptomics analysis of interactive effects of benzene, trichloroethylene and methyl mercury within binary and ternary mixtures on the liver and kidney following subchronic exposure in the rat
Hendriksen, Peter J.M., Freidig, Andreas P., Jonker, Diana, Thissen, Uwe, Bogaards, Jan J.P., Mumtaz, Moiz M., Groten, John P., Stierum, Rob H.
Published in Toxicology and applied pharmacology (01.12.2007)
Published in Toxicology and applied pharmacology (01.12.2007)
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Developing computational model-based diagnostics to analyse clinical chemistry data
VAN SCHALKWIJK, Daniël B, VAN BOCHOVE, Kees, VAN OMMEN, Ben, FREIDIG, Andreas P, VAN SOMEREN, Eugene P, VAN DER GREEF, Jan, DE GRAAF, Albert A
Published in Briefings in bioinformatics (01.07.2010)
Published in Briefings in bioinformatics (01.07.2010)
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An in vitro and in silico study on the flavonoid-mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) through Caco-2 monolayers
Schutte, Maaike E., Freidig, Andreas P., van de Sandt, Johannes J.M., Alink, Gerrit M., Rietjens, Ivonne M.C.M., Groten, John P.
Published in Toxicology and applied pharmacology (01.12.2006)
Published in Toxicology and applied pharmacology (01.12.2006)
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Journal Article
Quercetin increases the bioavailability of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) in rats
Schutte, Maaike E., Alink, Gerrit M., Freidig, Andreas P., Spenkelink, Bert, Vaessen, Judith C.H., van de Sandt, Johannes J.M., Groten, John P., Rietjens, Ivonne M.C.M.
Published in Food and chemical toxicology (01.11.2008)
Published in Food and chemical toxicology (01.11.2008)
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Journal Article
Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents
Hissink, A.M., Krüse, J., Kulig, B.M., Verwei, M., Muijser, H., Salmon, F., Leenheers, L.H., Owen, D.E., Lammers, J.H.C.M., Freidig, A.P., McKee, R.H.
Published in Neurotoxicology (Park Forest South) (01.07.2007)
Published in Neurotoxicology (Park Forest South) (01.07.2007)
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