Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol
Liu, Su-Yang, Aliyari, Roghiyh, Chikere, Kelechi, Li, Guangming, Marsden, Matthew D., Smith, Jennifer K., Pernet, Olivier, Guo, Haitao, Nusbaum, Rebecca, Zack, Jerome A., Freiberg, Alexander N., Su, Lishan, Lee, Benhur, Cheng, Genhong
Published in Immunity (Cambridge, Mass.) (24.01.2013)
Published in Immunity (Cambridge, Mass.) (24.01.2013)
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Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis
Johnson, Bryan A., Xie, Xuping, Bailey, Adam L., Kalveram, Birte, Lokugamage, Kumari G., Muruato, Antonio, Zou, Jing, Zhang, Xianwen, Juelich, Terry, Smith, Jennifer K., Zhang, Lihong, Bopp, Nathen, Schindewolf, Craig, Vu, Michelle, Vanderheiden, Abigail, Winkler, Emma S., Swetnam, Daniele, Plante, Jessica A., Aguilar, Patricia, Plante, Kenneth S., Popov, Vsevolod, Lee, Benhur, Weaver, Scott C., Suthar, Mehul S., Routh, Andrew L., Ren, Ping, Ku, Zhiqiang, An, Zhiqiang, Debbink, Kari, Diamond, Michael S., Shi, Pei-Yong, Freiberg, Alexander N., Menachery, Vineet D.
Published in Nature (London) (11.03.2021)
Published in Nature (London) (11.03.2021)
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SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species
Moustaqil, Mehdi, Ollivier, Emma, Chiu, Hsin-Ping, Van Tol, Sarah, Rudolffi-Soto, Paulina, Stevens, Christian, Bhumkar, Akshay, Hunter, Dominic J. B., Freiberg, Alexander N., Jacques, David, Lee, Benhur, Sierecki, Emma, Gambin, Yann
Published in Emerging microbes & infections (01.01.2021)
Published in Emerging microbes & infections (01.01.2021)
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Favipiravir (T-705) protects against Nipah virus infection in the hamster model
Dawes, Brian E., Kalveram, Birte, Ikegami, Tetsuro, Juelich, Terry, Smith, Jennifer K., Zhang, Lihong, Park, Arnold, Lee, Benhur, Komeno, Takashi, Furuta, Yousuke, Freiberg, Alexander N.
Published in Scientific reports (15.05.2018)
Published in Scientific reports (15.05.2018)
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The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response
Bharaj, Preeti, Wang, Yao E, Dawes, Brian E, Yun, Tatyana E, Park, Arnold, Yen, Benjamin, Basler, Christopher F, Freiberg, Alexander N, Lee, Benhur, Rajsbaum, Ricardo
Published in PLoS pathogens (01.09.2016)
Published in PLoS pathogens (01.09.2016)
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ISG15 deficiency and increased viral resistance in humans but not mice
Speer, Scott D., Li, Zhi, Buta, Sofija, Payelle-Brogard, Béatrice, Qian, Li, Vigant, Frederic, Rubino, Erminia, Gardner, Thomas J., Wedeking, Tim, Hermann, Mark, Duehr, James, Sanal, Ozden, Tezcan, Ilhan, Mansouri, Nahal, Tabarsi, Payam, Mansouri, Davood, Francois-Newton, Véronique, Daussy, Coralie F., Rodriguez, Marisela R., Lenschow, Deborah J., Freiberg, Alexander N., Tortorella, Domenico, Piehler, Jacob, Lee, Benhur, García-Sastre, Adolfo, Pellegrini, Sandra, Bogunovic, Dusan
Published in Nature communications (19.05.2016)
Published in Nature communications (19.05.2016)
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Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity
Johnson, Bryan A, Hage, Adam, Kalveram, Birte, Mears, Megan, Plante, Jessica A, Rodriguez, Sergio E, Ding, Zhixia, Luo, Xuemei, Bente, Dennis, Bradrick, Shelton S, Freiberg, Alexander N, Popov, Vsevolod, Rajsbaum, Ricardo, Rossi, Shannan, Russell, William K, Menachery, Vineet D
Published in Journal of virology (15.11.2019)
Published in Journal of virology (15.11.2019)
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Pteropus vampyrus TRIM40 Is an Interferon-Stimulated Gene That Antagonizes RIG-I-like Receptors
van Tol, Sarah, Hage, Adam, Rajsbaum, Ricardo, Freiberg, Alexander N
Published in Viruses (25.10.2023)
Published in Viruses (25.10.2023)
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Journal Article
Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway
Park, Arnold, Yun, Tatyana, Vigant, Frederic, Pernet, Olivier, Won, Sohui T, Dawes, Brian E, Bartkowski, Wojciech, Freiberg, Alexander N, Lee, Benhur
Published in PLoS pathogens (01.05.2016)
Published in PLoS pathogens (01.05.2016)
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Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing
Ochoa, Lorenzo F., Kholodnykh, Alexander, Villarreal, Paula, Tian, Bing, Pal, Rahul, Freiberg, Alexander N., Brasier, Allan R., Motamedi, Massoud, Vargas, Gracie
Published in Scientific reports (06.09.2018)
Published in Scientific reports (06.09.2018)
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Role of Protein Phosphatase 1 in Dephosphorylation of Ebola Virus VP30 Protein and Its Targeting for the Inhibition of Viral Transcription
Ilinykh, Philipp A., Tigabu, Bersabeh, Ivanov, Andrey, Ammosova, Tatiana, Obukhov, Yuri, Garron, Tania, Kumari, Namita, Kovalskyy, Dmytro, Platonov, Maxim O., Naumchik, Vasiliy S., Freiberg, Alexander N., Nekhai, Sergei, Bukreyev, Alexander
Published in The Journal of biological chemistry (15.08.2014)
Published in The Journal of biological chemistry (15.08.2014)
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The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains
Lubaki, Ndongala M, Ilinykh, Philipp, Pietzsch, Colette, Tigabu, Bersabeh, Freiberg, Alexander N, Koup, Richard A, Bukreyev, Alexander
Published in Journal of Virology (01.07.2013)
Published in Journal of Virology (01.07.2013)
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Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication
Rodríguez-Salazar, Carlos A, van Tol, Sarah, Mailhot, Olivier, Gonzalez-Orozco, Maria, Galdino, Gabriel T, Warren, Abbey N, Teruel, Natalia, Behera, Padmanava, Afreen, Kazi Sabrina, Zhang, Lihong, Juelich, Terry L, Smith, Jennifer K, Zylber, María Inés, Freiberg, Alexander N, Najmanovich, Rafael J, Giraldo, Maria I, Rajsbaum, Ricardo
Published in PLoS biology (01.02.2024)
Published in PLoS biology (01.02.2024)
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The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity
Hage, Adam, Bharaj, Preeti, van Tol, Sarah, Giraldo, Maria I., Gonzalez-Orozco, Maria, Valerdi, Karl M., Warren, Abbey N., Aguilera-Aguirre, Leopoldo, Xie, Xuping, Widen, Steven G., Moulton, Hong M., Lee, Benhur, Johnson, Jeffrey R., Krogan, Nevan J., García-Sastre, Adolfo, Shi, Pei-Yong, Freiberg, Alexander N., Rajsbaum, Ricardo
Published in Cell reports (Cambridge) (08.03.2022)
Published in Cell reports (Cambridge) (08.03.2022)
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The Susceptibility of BALB/c Mice to a Mouse-Adapted Ebola Virus Intravaginal Infection
Escaffre, Olivier, Juelich, Terry L, Smith, Jennifer K, Zhang, Lihong, Bourne, Nigel, Freiberg, Alexander N
Published in Viruses (01.07.2023)
Published in Viruses (01.07.2023)
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Ubiquitin-regulated nuclear-cytoplasmic trafficking of the Nipah virus matrix protein is important for viral budding
Wang, Yao E, Park, Arnold, Lake, Michael, Pentecost, Mickey, Torres, Betsabe, Yun, Tatyana E, Wolf, Mike C, Holbrook, Michael R, Freiberg, Alexander N, Lee, Benhur
Published in PLoS pathogens (01.11.2010)
Published in PLoS pathogens (01.11.2010)
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Efficacy and Immunogenicity of a Recombinant Vesicular Stomatitis Virus-Vectored Marburg Vaccine in Cynomolgus Macaques
Camargos, Vidyleison N, Rossi, Shannan L, Juelich, Terry L, Smith, Jennifer K, Vasilakis, Nikos, Freiberg, Alexander N, Nichols, Rick, Fusco, Joan
Published in Viruses (24.07.2024)
Published in Viruses (24.07.2024)
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Rift Valley fever virus 78kDa envelope protein attenuates virus replication in macrophage-derived cell lines and viral virulence in mice
Terasaki, Kaori, Kalveram, Birte, Johnson, Kendra N, Juelich, Terry, Smith, Jennifer K, Zhang, Lihong, Freiberg, Alexander N, Makino, Shinji
Published in PLoS neglected tropical diseases (01.09.2021)
Published in PLoS neglected tropical diseases (01.09.2021)
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Journal Article
Favipiravir (T-705) inhibits Junín virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever
Gowen, Brian B, Juelich, Terry L, Sefing, Eric J, Brasel, Trevor, Smith, Jennifer K, Zhang, Lihong, Tigabu, Bersabeh, Hill, Terence E, Yun, Tatyana, Pietzsch, Colette, Furuta, Yousuke, Freiberg, Alexander N
Published in PLoS neglected tropical diseases (01.12.2013)
Published in PLoS neglected tropical diseases (01.12.2013)
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